*An off-label use of a medication is a use that is not FDA-approved. Prescribers can decide to use a medication off-label because, in their professional judgment, they believe it may offer a benefit to someone.
Antidepressants have long been associated with certain side effects including weight gain, and Effexor is no exception. While gaining weight on Effexor can be concerning for some, there are healthy ways to manage this. Exercising, talking with a dietitian, and maintaining a nutritious diet can help you prevent further weight gain while taking Effexor.
If you want to discuss your current prescription with a provider or are considering a prescription for Effexor, an online psychiatry platform can be a good place to start. Talkiatry and Brightside Health offer psychiatric assessments and prescription consultation, and can address concerns about potential weight changes while taking Effexor.
What Is Effexor (Venlafaxine)?
Effexor (venlafaxine) is FDA-approved for the treatment of depression, anxiety disorders, and other mental health conditions.1 Effexor belongs to the serotonin and norepinephrine reuptake inhibitors (SNRIs) class of medications that plays an important role in regulating serotonin and norepinephrine levels in the brain. In turn, a person can experience improvements in their overall mood and mental well-being.
Online Psychiatry and Medication Management Covered by Insurance
Talkiatry can match you with a real psychiatrist who takes your insurance and is seeing new patients. They’re in-network with major insurers and offer medication management. Get started with a short online assessment
Why Does Effexor Cause Weight Gain?
Like many other antidepressants, Effexor may cause weight gain. It’s important to note that the extent of weight gain varies from individual to individual and can be influenced by several factors, including one’s diet, exercise habits, genetics, and other medications being taken. However, it is believed that Effexor increases a person’s appetite and influences their desire for carbohydrate-rich foods. This will likely influence their weight over time. Conversely, for some individuals, taking Effexor can result in the opposite effect, resulting in decreased appetite and weight loss.
Do Other Antidepressants Cause Weight Gain?
Many antidepressants are associated with weight gain. For example, both Effexor and other SNRIs or SSRIs work in the same way to improve a person’s depression or anxiety symptoms. Improving an individual’s mood can contribute to an increased appetite. If depression had caused weight loss, that weight might be regained as depression is treated.
Short-Term vs. Long-Term Impacts on Weight Gain
Both short- and long-term use of Effexor can result in weight gain. As one’s body adjusts to the medication, they are likely to experience some increase in weight. Long-term treatment with Effexor may lead to longer-lasting mood improvements, but this depends on the person and the duration of their medication plan.
Other Reasons for Weight Gain While Taking Effexor
Effexor is not the sole contributor to weight gain. Many other factors can influence a person’s weight. However, it is possible to curb weight gain and maintain a healthy diet while remaining on medication. Eating excessively without increasing physical activity will likely increase the risk of weight gain while taking Effexor.
Ways to Manage Effexor Weight Gain
Unhealthy levels of weight gain while taking Effexor can be concerning, especially if this continues well into treatment. However, there are healthy ways to limit this side effect while taking Effexor. Being sure to stay active and eat a nutritious diet will help you stay on track and in shape.
Below are ways to manage weight gain while taking Effexor:
- Adjust your dosage: If weight gain becomes persistent, talk with your doctor. Your physician can help taper your Effexor dosage if needed.
- Try another medication: If Effexor does not work for you and significantly affects your weight, your doctor can offer an alternative medication, such as Lexapro.
- Maintain a healthy diet: Eating healthy foods, such as vegetables and fruits, can help you manage your weight.3
- Stay physically active: A lack of exercise can lead to fat buildup in the body and further weight gain. Regular exercise burns excess calories and helps you stay in shape.2
- Work with a dietician: A dietician can help you determine a nutrition plan that works well for you and ensures you are able to maintain a healthy weight.
Other Side Effects of Effexor
Besides weight gain, Effexor can result in other side effects, including nausea, drowsiness, and headaches.3 However, if side effects become severe, it is important to seek immediate medical attention. The severity of adverse reactions typically depends on factors such as the individual’s age or pre-existing health conditions.
Common side effects of Effexor include:1
- Sweating
- Weight changes
- Dry mouth
- Sexual dysfunction
- Nervousness/restlessness
- Drowsiness
- Dizziness
- Headache
- Vomiting
- Sleeping problems
- Indigestion
- Nausea
Severe side effects of Effexor that may require immediate medical attention include:1
- Worsening anxiety symptoms
- Seizures
- Manic episodes
- Serotonin syndrome
- Vision problems
- Tremors
- Excessive bleeding
- Hyponatremia
- Suicidal thoughts and behaviors
Popular Choices for Online Psychiatry
Talkiatry – Safe, virtual mental health care from doctors who take insurance. Most psychiatry visits cost patients $30 or less* Take a short assessment.
Hims / Hers – Connect with a healthcare provider in 12 to 48 hours.** Free Assessment
*Includes copayment, deductible, coinsurance, and $0 Visits. Excludes no shows. **On average. Actual appointment times vary by state and individual patient.
Alternatives to Effexor
Most SSRIs, SNRIs, tricyclic antidepressants, and monoamine oxidase inhibitors can lead to weight gain in users. However, certain medications may be less likely to result in appetite, metabolism, and weight changes. A doctor can recommend alternatives to Effexor that work similarly, such as Lexapro (escitalopram), Pristiq (desvenlafaxine), or Trintellix (vortioxetine).
Questions to Ask Your Healthcare Team
Discuss your medical history with your doctor before taking any medication. This increases your chance of remaining safe while receiving treatment and that you are well-informed of any associated risks or side effects beforehand. Your doctor will determine which prescription suits your individual needs. However, it’s important to ask questions about your prescription so you can remain informed about healthy medication practices.
Questions to ask your care team about Effexor include:
- Am I at risk of increased weight gain if I am already taking other anxiety/depression medications?
- Will a previous history of weight gain on other medications make me more susceptible?
- What is the best dose of Effexor to limit weight gain?
- Are there substances I am taking that could interact with Effexor?
- When should I reach out to you about weight gain?
- How often should I come in for checkups while taking Effexor?
- Does insurance cover my medication?
- Is it possible to mix Effexor with other medications?
Final Thoughts
While every person reacts to medication differently, taking Effexor may result in weight gain. If you are unhappy with the side effects of Effexor or another antidepressant, discuss alternatives with your doctor. Your prescriber can recommend medications that may have a smaller impact on your weight.
Additional Resources
To help our readers take the next step in their mental health journey, Choosing Therapy has partnered with leaders in mental health and wellness. Choosing Therapy is compensated for marketing by the companies included below.
Virtual Psychiatry
Talkiatry – Get help from a real doctor that takes your insurance. Talkiatry offers medication management and online visits with expert psychiatrists. Take the online assessment and have your first appointment in days. Free Assessment
Hims / Hers – If you’re living with anxiety or depression, finding the right medication match may make all the difference. Connect with a licensed healthcare provider in just 12 – 48 hours. Explore FDA-approved treatment options and get free shipping, if prescribed. No insurance required. Get Started
Free Prescription Discount Card
Optum Perks – Save up to 80% on most prescriptions. Optum Perks provides discounts at over 64,000 pharmacies nationwide. No memberships or costs to you, ever. It’s really that easy. Get your card and start saving. Get the discount card!
Talk Therapy
BetterHelp – Get support and guidance from a licensed therapist. BetterHelp has over 30,000 therapists who provide convenient and affordable online therapy. Take a Free Online Assessment and get matched with the right therapist for you. Take free assessment
Anxiety Newsletter
A free newsletter from Choosing Therapy for those impacted by anxiety. Get helpful tips and the latest information. Sign Up
Online Anxiety Test
A few questions from Talkiatry can help you understand your symptoms and give you a recommendation for what to do next.
Best Online Psychiatry Services
Online psychiatry, sometimes called telepsychiatry, platforms offer medication management by phone, video, or secure messaging for a variety of mental health conditions. In some cases, online psychiatry may be more affordable than seeing an in-person provider. Mental health treatment has expanded to include many online psychiatry and therapy services. With so many choices, it can feel overwhelming to find the one that is right for you.