Victoza for Weight Loss: Uses, Dosage, Side Effects, & Warnings

What Is Victoza?

Victoza, containing liraglutide, is an FDA-approved GLP-1 agonist injection prescribed to lower blood sugar and mitigate major cardiovascular risks in adults and children (10 and older) with type 2 diabetes.¹

It is not recommended for type 1 diabetes and should not be combined with other liraglutide-containing medicines. No generic version is currently available for Victoza. FDA approval is usually granted if, during clinical trials, a medication’s safety and effectiveness for treating a specific condition have been demonstrated.

How Does Victoza Work for Weight Loss?

Victoza works by influencing hormones in the body, promoting a sense of fullness, and slowing down digestion. These effects may contribute to weight loss.

It’s important to note that while studies suggest its potential in weight management, using Victoza as a weight loss medication is considered an off-label application, meaning it’s not specifically FDA-approved for this purpose. Off-label use involves a healthcare provider prescribing a medication for a purpose not explicitly endorsed by the FDA.

Can I Take Victoza if I’m Not Diabetic?

Victoza has been shown to be effective at promoting weight loss for individuals with diabetes. While there is evidence suggesting its potential benefit for non-diabetic individuals as well, it’s essential to approach this with caution.

The use of Victoza for weight loss in non-diabetic individuals is considered an off-label application, meaning it’s not definitively approved for this purpose. Before considering Victoza for weight loss, consult with a healthcare professional to discuss potential risks and benefits based on individual health needs.

Is Victoza Safe for Weight Loss?

Victoza (liraglutide) appears to be a potentially effective option for weight loss. Clinical trials show a consistent weight loss of 4 to 6 kg (8-13 lb) when combined with diet and exercise, with more patients achieving significant weight loss compared to a placebo.²

Common side effects are mainly gastrointestinal and occur early in treatment. While recent studies highlight cardiovascular benefits, more research is needed for a comprehensive understanding of its long-term efficacy and safety.

How Effective is Victoza for Weight Loss?

Research indicates that liraglutide, the active ingredient in Victoza, may be effective and safe for weight loss in non-diabetic individuals. Studies show significant weight loss and a higher likelihood of losing body weight with this medication. While it may produce side effects for some people.³

Side Effects of Victoza for Weight Loss

Common side effects of Victoza for weight loss may include nausea, diarrhea, vomiting, decreased appetite, indigestion, and constipation. These side effects may be temporary as your body adjusts to the medication, or they may last for as long as you continue to take the medication. It’s essential to discuss any concerns with a healthcare professional to determine the best course of action based on individual health needs.

Common Side Effects of Victoza for Weight Loss

Common side effects of Victoza for weight loss may include nausea, diarrhea, vomiting, decreased appetite, indigestion, and constipation. While these side effects are generally mild, individuals experiencing persistent or severe symptoms should seek medical attention.

Common side effects of Victoza include:¹

• Nausea
• Diarrhea
• Vomiting
• Decreased appetite
• Indigestion
• Constipation

*All medications, including Victoza, can cause side effects which can be mild or serious. This is not a comprehensive list of all possible side effects. You should talk with your doctor about any questions you have and to understand the potential side effects and benefits of any medication.

Serious Side Effects of Victoza

Victoza may lead to serious side effects requiring prompt medical attention, including pancreatitis with severe abdominal pain, low blood sugar symptoms (dizziness, confusion), kidney problems, gallbladder issues (abdominal pain, jaundice), and serious allergic reactions. Rapid heartbeats are also a concern. If serious symptoms arise, seek immediate medical care.

Serious side effects of Victoza include:¹

• Pancreatitis
• Low blood sugar (hypoglycemia)
• Kidney problems (kidney failure)
• Serious allergic reactions
• Gallbladder problems
• Abdominal pain
• Yellowing of skin or eyes (jaundice)
• Fever
• Rapid heartbeats

*All medications, including Victoza, can cause side effects which can be mild or serious. This is not a comprehensive list of all possible side effects. You should talk with your doctor about any questions you have and to understand the potential side effects and benefits of any medication.

Allergic Reactions to Victoza

Allergic reactions to Victoza may occur in individuals with a history of serious allergies to liraglutide or any of its ingredients. Symptoms include swelling of the face, difficulty breathing, severe rash, fainting, or rapid heartbeat. Those with known allergies to Victoza components should avoid its use, and prompt medical attention is essential if any allergic reactions manifest.

Allergic reactions to semaglutide may include:¹

• Swelling of face, lips, tongue, or throat
• Difficulty breathing or swallowing
• Severe rash or itching
• Fainting or feeling dizzy
• Rapid heartbeat
• Upset stomach or vomiting
• Diarrhea
• Shaking or tremors
• Fatigue

If someone experiences allergic reactions to Victoza or semaglutide, seek immediate medical care. Do not ignore or delay seeking assistance if any signs of swelling, breathing difficulties, severe rashes, or other allergic reactions occur, as timely intervention can be critical for a positive outcome.

Victoza for Weight Loss Warnings & Precautions

Victoza warnings include potential risks of thyroid C-cell tumors and medullary thyroid carcinoma. Pancreatitis risk is heightened, and injection pens must not be shared to prevent blood-borne pathogen transmission. Hypoglycemia, acute kidney injury, hypersensitivity reactions, and gallbladder disease are additional concerns. Seek Immediate medical attention if any of these conditions are suspected.

Warnings and precautions for taking Victoza include:¹

• Boxed warning – the risk of thyroid cancer: Victoza may lead to thyroid C-cell tumors. Individuals with a history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2) should avoid Victoza. Regular monitoring may not reliably detect early signs.
• Allergic reactions: Symptoms include swelling, difficulty breathing, severe rash, fainting, or rapid heartbeat. If suspected, discontinue Victoza immediately and seek urgent medical attention.
• Pancreatitis: Watch for persistent severe abdominal pain and vomiting. If pancreatitis is suspected, stop Victoza promptly.
• Never share a Victoza pen between patients: Sharing injection pens poses a risk of transmitting blood-borne pa: Increased risk, especially with insulin or sulfonylureas. Patients may be educated on signs and symptoms to prevent severe low blood sugar.
• Acute kidney injury: Patients with kidney issues may have their renal functioning monitored.
• Hypersensitivity reactions: If serious reactions like anaphylaxis or angioedema occur, discontinue Victoza and seek immediate medical attention.
• Acute gallbladder disease: Patients may be monitored for gallbladder issues, with clinical follow-up recommended if needed.

What Are the Long-term Effects of Using Victoza?

Studies have shown positive outcomes in terms of glycemic control and weight loss over the short to medium term. However, long-term effects, especially concerning other aspects of health, require further investigation. Individuals using Victoza may be advised to continue regular follow-ups with their healthcare providers. These appointments can help providers and patients monitor any emerging developments and discuss the overall impact of taking Victoza.

There may be additional warnings or precautions with this medication. Talk with your healthcare provider about all risks before you start taking this medication.

Interactions With Victoza

Victoza may affect how other medications are absorbed, although clinical trials haven’t shown significant impacts. Caution is advised when taking oral medications alongside Victoza. Also, using Victoza with insulin or drugs that stimulate insulin release may increase the risk of low blood sugar. It’s essential to adjust insulin doses carefully to minimize this risk

4 substances you should avoid while taking Victoza include:¹

• Alcohol: Combining alcohol with Victoza may increase the risk of hypoglycemia (low blood sugar). It’s important to moderate alcohol intake and monitor blood sugar levels closely.
• Certain oral medications: Victoza’s impact on gastric emptying might affect the absorption of some oral medications. Caution is advised when taking oral medications alongside Victoza.
• Insulin or insulin-boosting medications: Using Victoza with insulin or drugs that stimulate insulin release may heighten the risk of low blood sugar. Dose adjustments should be carefully managed to avoid hypoglycemia.
• Herbal supplements: The interaction between Victoza and herbal supplements is not well-studied. It’s advisable to consult with a healthcare professional before combining them, as unexpected effects may occur.

This is not a comprehensive list of the possible interactions with Victoza. You should talk with your healthcare provider and your pharmacist about all prescription and over-the-counter medications, herbs, and supplements you take before starting Victoza.

Victoza Dosages for Weight Loss

Victoza dosages for weight loss vary. Because using Victoza for weight loss is an off-label use, dosages are not standard.

Victoza Forms & Strengths

Victoza is available in injection form, presenting as a clear 6 mg/mL solution in a pre-filled, single-patient-use pen. This pen offers convenient doses of 0.6 mg, 1.2 mg, or 1.8 mg for individualized treatment. The solution is not specified as extended-release, delayed-release, or sustained-release.

Victoza is available as a pre-filled, single-patient-use pen in the following dosages:¹

• 0.6 milligram (mg) dose
• 1.2 mg dose
• 1.8 mg dose

How Do I Take Victoza for Weight Loss?

To take Victoza for weight loss, follow your healthcare provider’s guidance precisely. Typically, it’s injected subcutaneously (between the skin and muscle) once daily. The injection can be administered at any time of day, independently of meals, in the abdomen, thigh, or upper arm.

Visually inspect the solution before each injection, ensuring it’s clear and particle-free. Follow the prescribed dosage and the instructions for taking Victoza. Taking Victoza consistently is important for effective and safe weight management.

When Is the Best Time to Take Victoza?

Victoza is designed for once-daily use, and the choice of when to take it is flexible. You can administer Victoza at any time of the day, with or without food. Establishing a consistent routine by taking it at the same time daily can help you take it more consistently. Also, there’s no need to adjust the dose based on meals or activity levels.

What Happens If I Miss a Dose of Victoza?

If you miss a dose of Victoza, take it as soon as you remember unless it’s close to the next scheduled dose. Never take extra doses to catch up. Do not abruptly stop taking Victoza without consulting your healthcare provider. If you have missed a dose and aren’t sure if you should take it, contact your pharmacist or healthcare professional.

How to Get Victoza for Weight Loss

To get Victoza for weight loss, your healthcare provider must first determine if the medication is appropriate for you. A healthcare professional, such as a primary care physician, endocrinologist, or doctor specializing in weight loss, will evaluate factors such as your overall health, the severity of your condition, and previous weight loss efforts before deciding if Victoza is an appropriate medication for you.

Who Is a Suitable Candidate for Victoza for Weight Loss?

Victoza is generally suitable for individuals with a body mass index (BMI) of 30 kg/m² or higher. It may also be prescribed for those with a BMI of 27 kg/m² or higher with at least one weight-related medical condition such as high blood pressure, type 2 diabetes, or high cholesterol.

Victoza Vs. Other Weight Loss Medications

Victoza is one of several weight loss medications available, some of which are FDA-approved for weight loss and others that are prescribed off-label. While side effects and cost need to be considered, these medications have shown effectiveness for people looking to achieve weight loss.

Saxenda, which shares the active ingredient liraglutide with Victoza, is FDA-approved for weight management in adults and adolescents.⁴ Wegovy, a semaglutide-based injection, is FDA-approved for obesity in adults and certain adolescents.⁵ Ozempic, another semaglutide injection medication, is designed for adults with type 2 diabetes, offering cardiovascular risk reduction.⁶

The selection between these options depends on individual health needs, weight loss objectives, and your prescriber’s recommendation.

Victoza in Combination With Lifestyle Changes

Using Victoza while adopting lifestyle changes can potentially enhance weight loss effects. Victoza’s GLP-1 agonist properties may contribute to improved blood sugar control and decreased appetite. While this may improve the chances for weight loss to occur, a healthy diet and regular exercise are still needed. The helpful effects of Victoza and lifestyle changes work together to make weight loss more achievable.

FAQs About Victoza for Weight Loss

These common questions and answers about utilizing Victoza for weight loss can help you understand its benefits,  possible side effects, and its potential to help you achieve weight loss.

How Quickly Can You Lose Weight on Victoza?

The timeframe for weight loss with Victoza varies among individuals, and may take several weeks for some to notice a difference. Victoza is FDA-approved as a diabetes treatment rather than a weight loss medication, and data about weight loss outcomes may be limited or inconclusive.³

How Much Weight Can I Lose on Victoza?

The effectiveness of Victoza for weight loss varies, as individual results may differ. Clinical studies have shown that liraglutide, the active ingredient in Victoza, consistently led to a 4 to 6 kg weight loss in non-diabetic individuals, with a higher proportion achieving significant weight loss compared to a placebo group. The exact amount of weight loss can depend on various factors, including lifestyle and adherence to treatment.³

How Effective Is Victoza for Weight Loss?

Victoza has been effective at inducing and maintaining weight loss in individuals with obesity. Comparable to other weight loss agents, it stands out with the added advantage of improving glycemic control. While studies support its efficacy, further research is required to understand its long-term effectiveness and safety.²

Can Victoza Be Used As a Standalone Weight Loss Treatment?

No, Victoza is not intended as a standalone weight loss treatment. Doctors prescribing Victoza off-label for weight loss recommend using the medication with lifestyle modifications, including a balanced diet and regular exercise.

Can I Stop Victoza Once I’ve Achieved My Weight Loss Goals?

Abruptly stopping Victoza may have consequences. Do not make any changes to your medication regimen unless directed by your prescriber. If a change is needed, they will guide you through the appropriate course of action.

Questions to Ask Your Healthcare Provider About Victoza for Weight Loss

You may have questions about Victoza for weight loss. Understanding how Victoza works and the potential risks and benefits is an important step for choosing an effective treatment.

Questions to ask your care team about Victoza for weight loss include:

• How safe is Victoza for weight loss?
• How long will it take for me to adjust to taking Victoza for weight loss?
• Am I at risk for more serious symptoms if I am already taking other medications?
• Will Victoza allow me to lose weight and keep it off long-term?
• Are there specific lifestyle changes or dietary considerations while on Victoza?
• Can I expect any side effects, and how can they be managed?
• Are there any interactions between Victoza and my current medications?
• What results can I realistically anticipate in terms of weight loss?
• How often should I follow up with you once I start Victoza?
• Is Victoza suitable for me if I have other health conditions?
• Are there any specific signs or symptoms I should monitor while on Victoza?
• Will Victoza impact my ability to engage in regular physical activity?
• How does Victoza compare to other weight loss treatments in terms of efficacy and safety?
• What should I do if I miss a dose or experience unexpected changes in my health?

How to Know if Victoza for Weight Loss Is Right for You

Determining if Victoza for weight loss is right for you involves a comprehensive assessment of various factors. Discuss your weight loss goals and medical history with your healthcare provider. Consideration of existing health conditions, medication interactions, and lifestyle factors is essential. If you have type 2 diabetes, Victoza might be a suitable option due to its dual benefits in managing blood sugar and aiding weight loss. Engage in open communication with your healthcare provider to explore potential benefits and risks, ensuring an informed decision aligns with your health needs and goals.