Auvelity Side Effects

Important Things to Know About Taking Auvelity

Before starting Auvelity, it’s important to understand what to expect in the first few weeks. Your prescriber will discuss your dosage and how to take your medication properly. They will also go over precautions, potential side effects you may experience, and what to do if they become a problem.

How Long Does It Take for Auvelity to Work?

It typically takes 4-8 weeks to become fully effective. Some may start to feel better after the first week or two. Each person may have a different response time based on how their body absorbs and processes the medication.

Can Auvelity Make You Feel Worse at First?

Yes, some people starting Auvelity may experience uncomfortable side effects such as increased dizziness and a headache.¹ Auvelity can also increase the risk of suicidal thoughts and behaviors in some people. If you experience worsened symptoms or side effects of any kind, contact your provider immediately.

What Happens If I Miss a Dose?

If you forget to take your Auvelity dose, take it as soon as you remember. If your next dose is due soon, skip the missed one and take your next scheduled dose. Never take two doses at once. Keep taking your medication consistently unless your prescriber gives you different instructions.¹

Who Experiences Side Effects More?

Some patients may experience more side effects from Auvelity than others. While predicting who may have a strong reaction is difficult, certain patients should be cautious.

Those Taking Other Medications

Combining Auvelity with other medications can increase the risk of side effects and other complications. Medications that increase serotonin in your body can be unsafe. This includes selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), two common types of antidepressants. Taking these medications with Auvelity can increase the risk of a serious condition called serotonin syndrome.This is not a complete list of medications that can interact with Auvelity.

Those With Certain Health Risks

Auvelity may not be safe for those with certain health risks. For example, young adults age up to age 24 have an increased risk of suicidal ideation when taking Auvelity. For those with a history of seizures, Auvelity may cause them to occur more frequently. Discussing your health history with your healthcare provider can help avoid these risks.

Those with a higher risk of side effects from Auvelity include anyone who:¹

• Has a history of seizures
• Has been diagnosed with anorexia nervosa or bulimia nervosa
• Is breastfeeding or plans to breastfeed
• Has high blood pressure
• Has a history of bipolar disorder, symptoms of mania or hypomania
• Has a history or risk of developing glaucoma
• Has a history of liver problems
• Has a history of kidney problems
• Has had prior allergic reactions to dextromethorphan hydrobromide or bupropion hydrochloride

How to Cope With Common Auvelity Side Effects

There are ways to cope with the most common Auvelity side effects*. Many may go away on their own during the first few weeks. If side effects persist or worsen, tell your provider as soon as possible.

Drowsiness

It’s common to feel drowsy when taking Auvelity. If it affects your daily activities or becomes worse, talk to your provider. They may adjust your dosage or the time you take your medication. Until you understand how Auvelity affects you, avoid driving or other tasks that require you to stay fully alert.

Digestive Symptoms

Some people experience digestive issues when taking Auvelity, such as nausea, constipation, and vomiting. To minimize these, follow meal timing recommendations for Auvelity. Also, drink plenty of water, eat smaller, more frequent meals, and avoid spicy foods.

Ginger or peppermint teas may help, but talk with your healthcare provider first. Prescription medication can interact with over-the-counter medications, herbal remedies, and even tea.

Sexual Side Effects

Auvelity may cause changes in sexual function for some people. Men taking Auvelity may experience erectile dysfunction, decreased sex drive, and delayed ejaculation. Women may have problems with orgasms and decreased sex drive.¹

Sexual side effects often improve over time. Scheduling sexual activity before taking a dose may also reduce the risk or impact of sexual side effects. Your provider may consider changing your dosage or switching medications if they keep bothering you.

*All medications, including Auvelity, can cause side effects which can be mild or serious. This is not a comprehensive list of all possible side effects. You should talk with your doctor about any questions you have and to understand the potential side effects and benefits of any medication.

More Ways to Manage Auvelity Side Effects

Here are more ways to cope with and reduce the impact of Auvelity side effects.

Practice Good Sleep Hygiene

Good sleep habits can make a big difference as your body adjusts to Auvelity. Try waking up and going to bed about the same time each day. A comfortable and relaxing sleep  environment is also important. If you become drowsy while taking Auvelity, avoid driving or operating machinery until you understand how it affects you.

Healthy Lifestyle Activities

A balanced diet, regular exercise, and proper rest are important for good physical and mental health. These habits can also help your body handle medication adjustments more smoothly.

Follow a Daily Routine

Following your normal routine is important, even if the medication hasn’t started working yet. Doing your regular daily activities can keep life more predictable and reduce stress as you adjust to the medication. Also, take your medication as prescribed and at the same time each day.

Consider Therapy

Psychotherapy can be a valuable tool for managing the impact of side effects. For in-person treatment, your primary care provider or insurance company can connect you with a provider. Or, your family or friends may recommend one.

To find an online therapist, an online therapist directory is a great starting point. Many online psychiatry platforms, such as Talkiatry and Brightside Health, also offer therapy services.

Should I Stop Taking Auvelity If I Start Feeling Side Effects?

Do not stop taking Auvelity unless your provider tells you to. If you experience side effects from your medication, tell your provider as soon as possible. They can help adjust your dosage, change the timing of your medication, or explore alternative treatments. If your provider determines that stopping your medication is best for you, they will provide a plan for tapering off safely.

When Should I Call My Doctor About Auvelity Side Effects?

Many people stop taking medication because of side effects. While some effects can be managed or fade away on their own, others may only disappear if the medication is stopped.  Side effects can occur even if you are taking your medication correctly.

Contact your provider as soon as possible if side effects persist or become hard to cope with. Although serious side effects are rare, they can happen and may require immediate medical care. Some may even be life-threatening. If you notice any of the serious side effects listed above, seek medical care right away.

How to Get a Prescription for Auvelity or Alternative Medications

To get a prescription for Auvelity or an alternative in person, start with an evaluation for your symptoms. Your primary care provider can help you get the process started. This may be a physician, nurse practitioner, or physician assistant. They may refer you to a psychiatrist or specialist to determine the best treatment plan, including medication options.

For an online prescription, you’ll also begin with an evaluation from an online psychiatric provider. We have carefully reviewed platforms like Talkiatry or Circle Medical which can prescribe non-controlled substances such as antidepressants.