Klonopin (Clonazepam) Side Effects: Everything You Need to Know

Common Side Effects of Klonopin

Klonopin can have various side effects, both common and less common. Common side effects of Klonopin include drowsiness, dizziness, and coordination problems. These effects are generally mild and may not require medical attention unless they persist or worsen. Other common side effects may include fatigue, memory problems, and difficulty concentrating.¹

However, there are less common side effects that may warrant medical attention. These can include confusion, depression, mood changes, hallucinations, and difficulty breathing. If you experience any of these less common side effects or any serious or persistent symptoms while taking Klonopin, it is important to seek medical attention promptly. Your healthcare provider can assess the situation and determine the appropriate course of action to ensure your well-being and safety.¹

Common side effects of Klonopin include:*²

• Dizziness
• Drowsiness
• Constipation
• Lethargy
• Fatigue
• Sedation
• Impaired coordination
• Blurred vision
• Irritability
• Lack of motivation
• Loss of libido

*Klonopin has a risk of side effects, including serious side effects. This is not a comprehensive list of all possible side effects. You should talk with your healthcare professional about the benefits and risks of any medication before starting treatment.

Serious Side Effects of Klonopin

While serious side effects of Klonopin are rare, they do require immediate medical attention. These serious side effects may include allergic reactions characterized by rash, itching, swelling, severe dizziness, or difficulty breathing. It is crucial to seek medical help if you experience any signs of an allergic reaction.

In some cases, Klonopin may also cause serious breathing difficulties, such as slowed or shallow breathing. Other severe side effects can include significant changes in mood or behavior, worsening depression, suicidal thoughts, or signs of liver problems like yellowing of the eyes or skin, dark urine, or persistent abdominal pain.¹

Serious side effects of Klonopin include:*²

• Breathing problems
• Personality changes
• Behavioral disturbance
• Ataxia (loss of balance and coordination)
• Increased frequency of seizures
• Thrombocytopenia (low platelet count in blood)
• Psychosis
• Worsening depression
• Increased risk of suicide
• Hallucinations
• Anterograde amnesia (inability to form new memories)
• Severe allergic reactions including rashes and trouble breathing

*Klonopin has a risk of side effects, including serious side effects. This is not a comprehensive list of all possible side effects. You should talk with your healthcare professional about the benefits and risks of any medication before starting treatment.

Long-term Complications of Klonopin

When used for an extended period, Klonopin may potentially lead to long-term complications that should be brought to the attention of a healthcare provider. Prolonged use of Klonopin can sometimes result in the development of physical dependence or addiction, especially when the medication is taken in higher doses or for longer durations than prescribed. Abruptly stopping the medication or reducing the dosage without medical guidance can trigger withdrawal symptoms, including rebound anxiety, insomnia, irritability, and even seizures.

Klonopin is a long-acting and high-potency benzodiazepine, meaning it is generally not recommended for long-term use. Long-term use may result in an increased risk of falls as well as worsening depression and sexual dysfunction.²

Long-term complications of Klonopin include:²

• Increased risk of suicidal thoughts
• Potential harm to the liver
• Worsening depression
• Sexual dysfunction
• Increased risk of falls
• Increased risk of dependence and addiction

It’s important to remember that side effects can vary from person to person, and the list provided may not encompass all possible reactions. If you are considering taking Klonopin or have any concerns about its side effects, it is crucial to consult with your doctor or healthcare provider. They can provide personalized information, discuss potential risks, and help you make an informed decision. Your doctor is the best resource for ensuring you have a comprehensive understanding of the potential side effects associated with Klonopin.

Allergic Reactions

While allergic reactions to Klonopin are rare, they can occur and require immediate medical attention. Allergic reactions may manifest as skin rashes, hives, itching, or swelling, particularly of the face, tongue, or throat. In some cases, individuals may experience more severe allergic reactions, such as difficulty breathing, tightness in the chest, or anaphylaxis, which is a life-threatening reaction.

The frequency of allergic reactions to Klonopin is relatively low. However, if you develop any signs of an allergic reaction after taking Klonopin, it is crucial to seek immediate medical attention. Your healthcare provider can assess the situation, provide appropriate treatment, and determine whether you should discontinue the medication to prevent further allergic responses.³

Allergic reactions to Klonopin include:³

• Swelling
• Trouble breathing
• Skin rashes
• Low blood pressure
• Chest tightness
• Slow or rapid heart rate changes

If someone experiences allergic reactions to Klonopin or any other benzodiazepine, immediate medical attention is necessary. It is not recommended to try another benzodiazepine without medical guidance, as cross-reactivity among different medications in the same class is possible. Your healthcare provider can assess the situation and provide appropriate treatment if necessary. It is essential to work closely with your doctor to determine the safest and most effective course of action.¹

Interactions With Klonopin

Klonopin has the potential to interact with many medications, substances, and herbal supplements. It is important to speak with your provider to be aware of any potential interactions. Klonopin can increase the effects of other medications and substances like alcohol that affect the central nervous system, making it harder to breathe or maintain consciousness. Herbal supplements such as St. John’s Wort may also alter the effect of this medication.²

Six substances you should avoid while taking Klonopin include:²

• Other benzodiazepines: Other benzodiazepines taken together with Klonopin may cause an additive effect and an increased risk of dangerous side effects. Immediate help should be sought for anyone that may have ingested multiple benzodiazepines. Combining these medications may cause sedation, drowsiness, cognitive impairment or even falls, accidents, and trouble breathing.
• Opioids: Combining Klonopin with opioids, such as oxycodone or hydrocodone, can result in profound sedation, respiratory depression, and even overdose. Patients should seek immediate help if there are concerns about an overdose.
• Alcohol: Using alcohol with Klonopin can increase the sedative effects and impair coordination and judgment. Alcohol should be avoided while on this medication.
• Antidepressants: Some antidepressant medications, particularly SSRIs and SNRIs, can interact with Klonopin and increase the risk of sedation and central nervous system depression.
• St. John’s Wort: Herbal supplements like St. John’s Wort may induce the metabolism of Klonopin, reducing its effectiveness and potentially leading to decreased therapeutic effects.
• Sedatives/Hypnotics: Concurrent use of other sedatives or hypnotics such as barbiturates, can potentiate the sedating effects of Klonopin and increase the risk of respiratory depression.

Who Experiences the Most Side Effects on Klonopin?

Individuals can have different experiences with benzodiazepines, including Klonopin, and may exhibit different side effects and frequencies of occurrence. Primary factors include old age, poor overall health, and metabolic disorders.

Certain health conditions may increase the likelihood of developing side effects or experiencing more severe reactions. For example, older individuals or individuals with respiratory disorders, liver or kidney impairment, a history of substance abuse, or mental health conditions may be more susceptible to adverse effects.⁴

Klonopin Frequently Asked Questions (FAQ) About Side Effects

Taking Klonopin can raise multiple concerns for individuals considering its use. These concerns may include worries about potential side effects, the risk of dependency or addiction, long-term effects on cognitive function, and potential interactions with other medications or substances. Additionally, some individuals may have concerns about the effectiveness of Klonopin in treating their specific condition or whether there are alternative treatment options available.

How Long Do Klonopin Side Effects Tend to Last?

The duration of side effects from Klonopin can vary depending on factors such as individual metabolism, dosage, and duration of use. Common side effects like drowsiness or dizziness typically subside within a few hours after administration. However, certain side effects, such as cognitive impairments or changes in mood, may persist for a longer period.²

Do Klonopin Side Effects Vary Based on the Dosage?

Yes, the dosage of Klonopin can influence the frequency and severity of side effects. Higher doses of Klonopin are more likely to cause stronger and more pronounced side effects compared to lower doses. It is important to follow the prescribed dosage and discuss any concerns or observed side effects with your healthcare provider.¹

Are Benzodiazepines Safe?

They have addictive properties and it is dangerous to mix these medications with alcohol, pain medications, or sleeping pills. However, when dosed correctly, benzodiazepines are frequently prescribed for anxiety because they are effective at helping to manage and reduce symptoms of anxiety.

Can I Become Addicted to Klonopin?

Anxiety medications, such as Klonopin are meant for short-term use. However, some people with anxiety continue to take these medications for long periods of time. Unfortunately, physical dependence or drug tolerance can result. This may lead to a diminished effect from the drug and the individual feeling the need to take more to get a similar effect.⁴

Klonopin Withdrawal

Benzodiazepine withdrawal can manifest with symptoms such as anxiety, insomnia, irritability, and seizures. Immediate medical care is crucial if someone experiences withdrawal symptoms, as benzodiazepines can lead to physical dependence when used for a prolonged period. Benzodiazepine withdrawal can also result in more severe effects like hallucinations, depersonalization, and heightened sensitivity to light and sound.⁴

If someone feels physically dependent on benzodiazepines like Klonopin, seeking professional help from a healthcare provider or addiction specialist is essential. Withdrawal symptoms can occur as soon as a few hours to a few days after stopping benzodiazepines, emphasizing the importance of a carefully managed tapering process under medical supervision to minimize the risks associated with withdrawal.⁴

Other Warnings & Precautions For Taking Klonopin

Before taking Klonopin, it is important to be aware of several warnings and precautions associated with its use. Klonopin may cause drowsiness, dizziness, and impaired coordination, which can affect one’s ability to drive or operate machinery. It is essential to avoid activities that require mental alertness until the individual knows how Klonopin affects them.¹

Additionally, Klonopin should not be abruptly stopped as it may result in withdrawal symptoms or seizures. Tapering off the medication under medical supervision is recommended. It is also crucial to inform healthcare providers about any history of substance abuse, depression, or suicidal thoughts, as Klonopin may exacerbate these conditions.¹

Precautions for taking Klonopin include:¹

• Use while pregnant/breastfeeding: Discuss the use of Klonopin during pregnancy with your provider. The medication may pose risks to the developing fetus or infant, and a careful evaluation of the benefits and potential risks is necessary.
• Use in older adults: Klonopin can increase the risk of falls and accidents, resulting in fractures or other injuries. Moreover, benzodiazepines can have a negative impact on memory and cognition, potentially exacerbating age-related cognitive decline or dementia.
• Drowsiness and impaired coordination: Klonopin may cause drowsiness, dizziness, and coordination problems. It is important to avoid driving, operating machinery, or engaging in activities that require mental alertness until you know how the medication affects you.
• Substance abuse and mental health: Inform your healthcare provider about any history of substance abuse, depression, or suicidal thoughts, as Klonopin may worsen these conditions. Close monitoring and appropriate management are essential.

Questions to Ask Your Healthcare Provider About Klonopin Side Effects

To know more about the potential side effects of Klonopin,have open and proactive communication with your healthcare team.

Questions to ask your care team when considering the side effects of Klonopin may include:

• Can I use Klonopin along with therapy to treat anxiety?
• How long will it take for me to adjust to taking Klonopin?
• Am I at risk for more severe symptoms if I am already taking medication for anxiety, depression, or other mental health conditions?
• Will a previous history of addiction make me more susceptible to dependency?
• What is the best dosage to ensure fewer side effects?
• Are there drugs I am taking that could have negative interactions?
• When should I reach out to you if I am experiencing side effects?
• Is there anything I should tell my therapist about this new medication?
• How long will this medication last when I take it?
• Will I remain on this medication indefinitely or for a set amount of time?
• Is there any monitoring or follow-up required for taking this medication?

In My Experience

In my experience as a pharmacist, I think it’s important to consider how the side effects of any medication can affect a person’s quality of life. With a medication like Klonopin, it’s important to weigh how much benefit someone is receiving versus the potential side effects from a medication like this, usually used on an irregular basis for most cases. It is also important to discuss with your doctor any changes while on medications like benzodiazepines as they come with interactions and side effects to watch out for, especially in older patients or those with existing mental health conditions or previous substance abuse. When used correctly though, Klonopin can provide relief for anxiety and other conditions when the benefits of treatment outweigh the potential side effects.