Trintellix Dosage: Strengths, Form, How to Take, & More

Trintellix Dosage for Adults With Depression

Trintellix is used to treat major depressive disorder in adults. The dosage may be adjusted for older adults based on individual needs and medical considerations.¹ Improvement in depression symptoms may take several weeks after starting treatment.² Follow your healthcare provider’s guidance on how to treat depression with Trintellix and attend regular follow-up visits for effective management.

Trintellix Forms & Strengths

Trintellix is available in oral tablets with strengths of 5mg, 10mg, and 20mg. The selection of a specific form, strength, and dosage depends on individual factors such as the condition being treated, medical history, and the patient’s response to the medication.¹ Prescribers consider these criteria to determine the most suitable option for each patient’s specific needs and treatment goals.

Trintellix is available in the following forms and strengths:¹

• 5 milligrams (mg) oral tablet
• 10 milligrams (mg) oral tablet
• 20 milligrams (mg) oral tablet

Take Trintellix as prescribed by your healthcare provider to maximize its effectiveness. For oral tablets, follow the recommended dosage. The drug can be taken with or without food, depending on your preference and how it affects you. Some people may find that taking it with food helps reduce potential stomach upset. In contrast, others may prefer taking it on an empty stomach. But always take the medicine per your prescribed treatment plan.

Here is Trintellix dosage information for adults with depression:¹

• Typical starting dosage: The usual starting Trintellix dosing in adults with depression is 10 mg daily, taken orally, with or without food.
• Dosage increases: Depending on personal tolerance and response. The dosage might be increased to 20 mg daily after one to two weeks of treatment.
• Maximum dosage: The maximum recommended daily dosage of Trintellix is 20 mg. Follow your healthcare provider’s instructions, and don’t exceed this dose without their guidance.

What if I Miss a Dose of Trintellix?

If you miss or stop taking your regular dose of Trintellix, you may experience potential withdrawal effects such as dizziness, nausea, and mood changes.¹ If you need to get back on track with your prescription, contact your healthcare provider for guidance on how to resume your regimen safely or taper off gradually.

Some individuals experiencing initial Trintellix side effects may stop taking the medication. Others may stop or reduce their use because they start to feel better. However, it’s crucial to continue taking the medication as prescribed to maintain its effectiveness and avoid potential relapse or worsening of symptoms.

Trintellix Withdrawal

Trintellix is not typically associated with physical dependence.² Still, abruptly stopping the medication may lead to antidepressant withdrawal, also known as antidepressant discontinuation syndrome.⁴ If you experience withdrawal symptoms or want to stop the medication, seek medical help to discuss a proper tapering plan.

Symptoms of withdrawal from Trintellix include:¹

• Nausea
• Dizziness
• Fatigue
• Irritability
• Headache
• Insomnia
• Anxiety

Trintellix Dosage FAQs

Some people are concerned about Trintellix dosage or potential adjustments when switching from another antidepressant. Many share common questions about possible withdrawal effects, side effects, and the off-label use of Trintellix for other mental health conditions beyond major depressive disorder.

Here are some frequently asked questions about Trintellix dosage:

• Will my Trintellix dosage change if I switch to another antidepressant? It depends. When transitioning from one antidepressant to Trintellix, your healthcare provider will carefully evaluate your situation. Some adjustments could be based on factors such as your previous medication, your response to treatment, and any potential drug interactions.
• Can Trintellix be used to treat other mental health conditions? While Trintellix is approved for treating major depressive disorder, it is not limited to this use alone. Sometimes, healthcare providers may prescribe Trintellix off-label to address other mental health conditions.² Still, this decision is based on the prescriber’s clinical judgment and individual patient needs.
• What is the typical starting dosage for Trintellix? The typical starting dosage for Trintellix is 10 milligrams (mg) once daily. However, your healthcare provider may adjust the Trintellix dosing based on your individual response and tolerability.
• Can Trintellix dosage be increased? Yes, after a minimum of 1 to 2 weeks of treatment, your doctor may increase the Trintellix dosage to 20 mg once a day if necessary. Further dosage adjustments will be based on your specific needs and how well you respond to the medication.

Factors Affecting Trintellix Dosage

A responsible and thorough prescriber will consider various factors from your health history. For instance, the prescriber will record any existing medical ailments, particularly issues with the liver or kidneys. In addition, they will consider your age and overall health status. They can ask about other medications you might be taking to avoid potential interactions.⁵ Your response to the drug will also be monitored to determine the appropriate dosage that suits you best.

How to Take Trintellix

The general instructions for taking Trintellix remain similar across different dosages. Trintellix is available in the following oral tablet forms and strengths: 5 milligrams (mg), 10 milligrams (mg), and 20 milligrams (mg).¹ As the doctor says, the medication is typically taken once daily, with or without meals.

The specific time of day to take Trintellix may vary depending on your individual preferences and how the medication affects you. Some people prefer to take it in the morning to align with their daily routine. In contrast, others may find it more suitable to take in the evening if they experience drowsiness as a side effect. Always follow what your doctor recommends about the ideal time to take Trintellix.

Can You Overdose on Trintellix?

Yes, it is possible to overdose on Trintellix. Taking more than the prescribed dosage can lead to serious health consequences. ¹ Doing so can contribute to a Trintellix overdose, resulting in uncomfortable and serious symptoms.

Signs of an overdose on Trintellix include:¹

• Dizziness
• Excessive sweating
• Rapid or irregular heartbeat
• Uncontrollable shaking or tremors
• Nausea and vomiting
• Severe headache
• Confusion or disorientation

What Should You Do If You Take Too Much Trintellix?

Get professional help right away if you suspect an overdose. Immediately call emergency services (911 in the US) to request emergency medical attention. Bring the medication bottle or packaging to the healthcare facility to provide accurate information for prompt and appropriate medical intervention. Then, follow your healthcare provider’s guidance for managing this scenario.

Questions to Ask Your Healthcare Provider About Trintellix Dosage

If you are interested in understanding Trintellix dosages, ask your doctor about the recommended starting dose, dosage adjustments, and potential side effects. Additionally, online psychiatry services can provide accessible and convenient options for discussing Trintellix treatment with a qualified psychiatrist.

Questions to ask your care team about Trintellix dosage include:

• How should I take Trintellix? Should it be taken with food or on an empty stomach?
• Are there any specific time frames I should take Trintellix during the day?
• What should I do if I accidentally miss a dose of Trintellix?
• Can I split or crush the Trintellix tablets if needed?
• How long does it typically take for Trintellix to start working and improve my symptoms?
• Will the dosage of Trintellix change if I switch to another antidepressant?
• Are there any special Trintellix dosing considerations based on my health history or medical conditions?
• What should I do if I experience any side effects while taking Trintellix?
• Can Trintellix be used to treat other mental health conditions besides depression?
• Are any information or resources available about Trintellix dosage adjustments during pregnancy or breastfeeding?

In My Experience

In my experience, seeking help for depression is a courageous step. Contact a compassionate psychiatrist or therapist who can offer your support and guidance. Reflecting on this topic, I’m reminded of the countless people I’ve had the privilege to support in their mental health journeys. It’s been a profound experience witnessing how the right medication dosage can make a difference in their lives.

Now, I understand that discussing medication dosages might feel daunting, but please know that you’re not alone. Seeking professional support for depression can pave the way for a comprehensive treatment plan, combining medication like Trintellix with therapy and other interventions.