Azstarys: Uses, Side Effects, Dosage, & More

How Does Azstarys Work?

Azstarys, as an ADHD medication, works by acting as a central nervous system stimulant. It affects certain chemicals in the brain, such as dopamine and norepinephrine, which play essential roles in regulating attention and behavior. By increasing the levels of these neurotransmitters, Azstarys helps improve focus, reduce impulsivity, and control hyperactivity, ultimately alleviating ADHD symptoms and enhancing the patient’s ability to manage daily tasks and activities.

What Are Azstarys Used to Treat?

Azstarys is FDA-approved to treat attention-deficit hyperactivity disorder (ADHD) in patients aged 6 years and older.² FDA approval means that after rigorous testing and evaluation, the U.S. Food and Drug Administration has determined that Azstarys is safe and effective for treating ADHD. This medication specifically targets ADHD symptoms, such as inattention, impulsivity, and hyperactivity, helping patients manage their condition and improve daily functioning.

Azstarys may be used off-label in some cases. Off-label use involves using the medication for conditions or age groups not specifically approved by the FDA based on clinical judgment and expertise.

Alternatives to Azstarys for ADHD

Several medications, including stimulants like methylphenidate and amphetamine-based medications, are FDA-approved to treat ADHD symptoms¹ Non-stimulant medications like atomoxetine are also approved for ADHD treatment⁴

Consulting with a healthcare provider is essential to determine the best medication for each individual’s unique needs and medical history, ensuring effective ADHD management.

Side Effects of Azstarys

Azstarys may cause both persistent side effects and temporary effects during adjustment, such as decreased appetite, nausea, insomnia, anxiety, and increased blood pressure.²

Some severe side effects, including abuse and dependence risks, heart-related issues, and psychiatric problems, require immediate attention.² Consult a healthcare provider to monitor and address any side effects during Azstarys treatment.

Common Side Effects of Azstarys

Azstarys may cause mild and common side effects like difficulty sleeping, dizziness, and loss of appetite, which usually improve as the body adjusts. If these side effects persist or become bothersome, consult a healthcare provider for guidance.

Common side effects of Azstarys include:*¹

• Decreased appetite
• Nausea
• Insomnia
• Anxiety
• Increased blood pressure
• Abdominal pain
• Dizziness

All medications, including Azstarys, can cause side effects that can be mild or serious. This is not a comprehensive list of all possible side effects. You should talk with your doctor about any questions you have and understand the potential side effects and benefits of any medication.

Serious Side Effects of Azstarys

While Azstarys can be beneficial for treating ADHD, it may also lead to some potentially serious side effects like abuse, mental health issues, and painful penis erection that require immediate medical attention. These effects should be closely monitored to ensure the safety of the patient.

Serious side effects of Azstarys may include:¹

• Abuse and Dependence
• Serious Cardiovascular Reactions
• Psychiatric Adverse Reactions
• Priapism (prolonged and painful erection)
• Long-Term Suppression of Growth

If any of these side effects are experienced while taking Azstarys, it is crucial to seek prompt medical care to address the issue appropriately.

All medications, including Azstarys, can cause side effects that can be mild or serious. This is not a comprehensive list of all possible side effects. You should talk with your doctor about any questions you have and understand the potential side effects and benefits of any medication.

Allergic Reactions to Azstarys

Allergic reactions to Azstarys can happen if someone is sensitive to serdexmethylphenidate, methylphenidate, or other parts of the medication. People with bad reactions to other methylphenidate products might also be at risk. Allergic symptoms may include rash, itching, and sometimes serious symptoms that need urgent attention.

Allergic reactions to Azstarys may include:¹

• Bronchospasm (constriction of the airways)
• Rash
• Pruritus (itching)
• Angioedema (swelling under the skin, often around the face and throat)
• Anaphylactic reactions (severe and potentially life-threatening allergic responses)

If someone experiences any allergic reaction to Azstarys, it is crucial to seek immediate medical attention. Depending on the individual’s medical history and specific allergic response, alternative medications may be considered for managing ADHD symptoms.

Azstarys Warnings & Precautions

Before taking Azstarys, be aware of potential warnings and precautions for safe usage. Evaluate medical history and health status carefully with healthcare providers before starting the medication.

Precautions for taking Azstarys include:¹

• Potential for abuse and dependence: Azstarys, like other CNS stimulants, can have a high potential for abuse and dependence. Healthcare providers should assess the risk of abuse before prescribing and monitor patients for signs of abuse or dependence during treatment.
• Serious cardiovascular reactions: There have been reports of sudden death, stroke, and heart attacks in adults on CNS stimulant treatment. Patients with structural heart abnormalities and serious heart issues should avoid using Azstarys.
• Blood pressure and heart rate increases: CNS stimulants can cause an increase in blood pressure and heart rate.
• Psychiatric adverse reactions: Azstarys may also induce manic episodes in individuals with bipolar disorder.
• Priapism: Prolonged and painful erections, known as priapism, have been reported in some patients taking methylphenidate products.
• Peripheral vasculopathy, including Raynaud’s phenomenon: Patients may experience intermittent and mild symptoms of feeling numb and cold, but careful observation is necessary. Seek medical evaluation for certain patients.
• Long-term suppression of growth: Pediatric patients on CNS stimulants may experience weight loss and slowed growth rate.

Interactions With Azstarys

It’s essential to be cautious about combining Azstarys with other medications, substances, or herbs, as it may lead to harmful effects. To ensure your safety, inform your healthcare provider about all the medicines and supplements you are taking.

4 substances you should avoid while taking Azstarys include:¹

• Monoamine Oxidase Inhibitors (MAOIs): Taking MAOIs with Azstarys can lead to a serious problem called hypertensive crisis, which can cause stroke or heart issues.
• Antihypertensive drugs: Azstarys might make drugs used for high blood pressure less effective, leading to uncontrolled blood pressure.
• Halogenated anesthetics: Using halogenated anesthetics with Azstarys during surgery can raise blood pressure and heart rate suddenly, which can be dangerous.
• Risperidone: If you take Azstarys and risperidone together and change the dose of either medicine, you might experience unwanted movements that need close monitoring.

To avoid any troubles, make sure to share all your medications and supplements with your healthcare provider before starting Azstarys.

Azstarys Cost & Prices

Azstarys can cost between $300 to $600 per month without insurance, and even with insurance, the out-of-pocket expenses can be significant. To reduce costs, patients can explore manufacturer savings programs, discount cards, or patient assistance programs. Unlike Adderall, Azstarys does not have a generic version available, making the brand version the only option, which may impact affordability for some patients.⁵

Azstarys Dosages for FDA-Approved Treatment

Azstarys is FDA-approved for ADHD treatment in pediatric patients (6 to 12 years) and adults and older pediatric patients (13 to 17 years) The typical starting dose for pediatric patients is 39.2 mg/7.8 mg once daily in the morning, which can be adjusted after one week up to a maximum of 52.3 mg/10.4 mg once daily. ^1,6

Adults and older pediatric patients start with the same dose and may increase to 52.3 mg/10.4 mg once daily after one week. Dosages vary based on age, weight, and individual response, so consult a healthcare provider for personalized guidance.

Azstarys Forms & Strengths

Azstarys comes in three capsule strengths: 26.1 mg/5.2 mg, 39.2 mg/7.8 mg, and 52.3 mg/10.4 mg, taken orally. The appropriate form and strength are determined based on factors like age, weight, and medical condition. Dosages may vary due to individual differences in medication metabolism. The effects typically begin within a few hours after ingestion.

Azstarys is available in the following forms and strengths:²

• 26.1 mg/5.2 mg (blue cap/grey body, imprinted with “286” on the cap and “KP415” on the body)
• 39.2 mg/7.8 mg (dark blue cap/grey body, imprinted with “429” on the cap and “KP415” on the body)
• 52.3 mg/10.4 mg (orange cap/grey body, imprinted with “5612” on the cap and “KP415” on the body)

How Should I Take Azstarys?

To take Azstarys, follow your healthcare provider’s instructions carefully. You can take it with or without food. The capsules should be swallowed whole, but if needed, you can open them and sprinkle the contents onto applesauce or mix them with water. However, never substitute Azstarys with other methylphenidate products without proper guidance, as this can lead to dosage errors and potential overdosage. It’s crucial to take medications as prescribed to ensure their effectiveness and safety.¹

What Happens If I Miss a Dose of Azstarys?

If you miss a dose of Azstarys, take it as soon as you remember unless it’s almost time for the next dose. Don’t take extra doses to catch up, and avoid stopping the medication abruptly. Consult your healthcare provider if you have concerns about missed doses or usage.

Can You Become Addicted to Azstarys?

Azstarys, similar to other CNS stimulants, carry a risk of abuse and addiction, even when used as prescribed. Prescribers should assess the risk and provide close monitoring, education on storage, and regular follow-up visits.

For those facing addiction, medical detox or supervised discontinuation may be necessary. Watch for signs of abuse like increased heart rate and hyperactivity, and seek medical attention if noticed.

Can You Overdose on Azstarys?

Yes, it is possible to overdose on Azstarys. An overdose can occur when too much of the medication is taken, leading to excessive stimulation of the central nervous system and sympathetic effects. Signs of an overdose may include nausea, vomiting, restlessness, confusion, hallucinations, convulsions, rapid heartbeat, high body temperature, and muscle twitching. If you suspect an overdose or notice these symptoms, seek immediate medical attention.¹

What Should You Do If You Take Too Much Azstarys?

If you take too much Azstarys, seek immediate medical help. Contact your healthcare provider or go to the nearest emergency room. In case of an overdose, medical professionals will provide supportive care and closely monitor your condition.¹ They may employ general measures used for overdosage management, ensuring proper breathing, oxygen supply, and monitoring vital signs and heart rhythm.

Questions to Ask Your Healthcare Provider About Azstarys

If you or a loved one have been diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) and are considering treatment options, you might want to know more about Azstarys. It is essential to discuss Azstarys with your doctor, psychiatrist, and therapist to make informed decisions about your ADHD management.

Questions to ask your care team about Azstarys include:

• How will Azstarys help manage my ADHD symptoms?
• What are the potential side effects of Azstarys, and how can they be managed?
• Is Azstarys safe to take with other medications I am currently using for anxiety or depression?
• What is the recommended dosage for me, and how should I take it (with or without food)?
• Are there any specific precautions I should take while on Azstarys?
• How long does it typically take for Azstarys to start working effectively?
• What should I do if I miss a dose?
• Can I open the capsules and sprinkle them on applesauce or add them to water if swallowing is difficult?
• Are there any potential drug interactions I should be aware of?
• Should I continue my therapy sessions while taking Azstarys, and should I discuss this medication with my therapist?
• If I experience any sexual side effects while on Azstarys, when should I reach out to my psychiatrist?
• Are there any lifestyle changes or behavioral strategies that can complement the effects of Azstarys?

If you need to change prescribers or prefer a more convenient option, online psychiatry services can be a good alternative for obtaining a new prescription or seeking advice from a qualified psychiatrist.

In My Experience

In my experience, discussing Azstarys with your doctor, psychiatrist, and therapist is crucial when considering ADHD treatment options. It’s essential to have an open dialogue about the benefits and potential side effects of the medication.

Seeking professional guidance ensures that you receive personalized care and the most appropriate dosage for your specific needs. Remember that managing ADHD involves a comprehensive approach, including therapy and support.

If you or someone you know is dealing with ADHD, know that there are effective treatments available, and seeking help is a positive step towards improving daily functioning and overall well-being. Trust your care team, follow their guidance, and be proactive in managing your ADHD to lead a fulfilling life.

For Further Reading

• 10 Tips for Healthy Living With ADHD as an Adult
• ADHD in Men: Signs, Symptoms, & Treatments
• What is ADHD?
• Azstarys Vs Adderall XR: What Is the Difference?