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  • What Is Strattera?What Is Strattera?
  • Forms & StrengthsForms & Strengths
  • Dosage for AdultsDosage for Adults
  • Dosage for ChildrenDosage for Children
  • How to TakeHow to Take
  • Miss a DoseMiss a Dose
  • OverdoseOverdose
  • Questions to AskQuestions to Ask
  • In My ExperienceIn My Experience
  • Additional ResourcesAdditional Resources

Strattera Dosage: Form, Strengths, How to Take & More

Pamela Wiltfang, PharmD, MPH, BA, CHES headshot

Author: Pamela Wiltfang, PharmD, MPH

Pamela Wiltfang, PharmD, MPH, BA, CHES headshot

Pamela Wiltfang PharmD, MPH, CHES, CHW

With 12+ years of experience, Pamela Wiltfang is an accomplished pharmacist with a focus on medication therapy management. Pamela has expertise in psychotropic meds, weight loss, sexual health, and sleep medication management.

See My Bio Editorial Policy
Headshot of Heidi Moawad, MD

Medical Reviewer: Heidi Moawad, MD Licensed medical reviewer

Headshot of Heidi Moawad, MD

Heidi Moawad MD

Heidi Moawad, MD is a neurologist with 20+ years of experience focusing on
mental health disorders, behavioral health issues, neurological disease, migraines, pain, stroke, cognitive impairment, multiple sclerosis, and more.

See My Bio Editorial Policy
Published: August 17, 2023
  • What Is Strattera?What Is Strattera?
  • Forms & StrengthsForms & Strengths
  • Dosage for AdultsDosage for Adults
  • Dosage for ChildrenDosage for Children
  • How to TakeHow to Take
  • Miss a DoseMiss a Dose
  • OverdoseOverdose
  • Questions to AskQuestions to Ask
  • In My ExperienceIn My Experience
  • Additional ResourcesAdditional Resources
Pamela Wiltfang, PharmD, MPH, BA, CHES headshot
Written by:

Pamela Wiltfang

PharmD, MPH, BA, CHES
Headshot of Benjamin Troy, MD
Reviewed by:

Heidi Moawad

MD
Brand name:
Strattera
Generic name:
Atomoxetine
Is the generic available:
Yes
Class of drug:
Selective Norepinephrine Reuptake Inhibitor
Boxed warning:
Yes
FDA-approved treatments:
ADHD
Common Off-label Uses (non-FDA approved):
Treatment-resistant depression, major depression
Common alternatives:

Concerta, Adderall, Clonidine

View Drug Class, FDA-Approved Uses, Off-Label Uses, and more

*An off-label use of a medication is a use that is not FDA-approved. Prescribers can decide to use a medication off-label because, in their professional judgment, they believe it may offer a benefit to someone.

Strattera is an FDA-approved non-stimulant medication used to treat attention deficit hyperactivity disorder (ADHD). The typical dosage for Strattera ranges from 10mg to 100mg. Providers will select a dose for patients determined by diagnosis, age, weight, medical history, how well the first doses work, and how well the medication is tolerated.

Your prescriber can answer questions about dosages and how to take Strattera. If you’re considering Strattera or want to discuss your current medication treatment with a provider, online psychiatry platforms such as Talkiatry and Brightside Health are a good place to start. They can connect you to a provider quickly, who can answer any questions you have about taking your medication and provide new prescriptions as appropriate.

Boxed Warning: Atomoxetine (Strattera) – Risk of suicidal thoughts and behavior

Click here to open and close the box warning container.
Atomoxetine, the active ingredient in Strattera, has a black box warning. These are the most serious types of warnings from the Food and Drug Administration (FDA). Atomoxetine can increase the risk of suicidal thoughts and behaviors in children, adolescents, and young adults. Regardless of your age, you should talk with your doctor about serious risks with atomoxetine and any other medications before starting treatment.

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What Is Strattera (Atomoxetine) & How Is It Used?

Strattera is an FDA-approved medication for treating attention deficit hyperactivity disorder (ADHD). Strattera is a non-stimulant, norepinephrine reuptake inhibitor. The exact way Strattera works in the body for ADHD is unknown. But it is thought to be caused by increasing naturally occurring chemicals in the brain to help promote attention and decrease symptoms of ADHD.1

Strattera also has off-label (non-FDA-approved) uses for the treatment of ADHD with social anxiety disorder and nocturnal enuresis (bed wetting).2, 3 An off-label use of medication means that it is not FDA-approved for that condition. Prescribers can decide to use a medication off-label because, in their professional judgment, they believe it may benefit someone.

Strattera Forms & Strengths

Strattera is available in capsules ranging from 10 mg to 100 mg. The right dosage for patients taking this medication may differ between individuals. Your doctor will consider a dose for you or your child that is determined by diagnosis, age, weight, medical history, how well the first and following doses are working, and how well you can tolerate the medication.1

Strattera is available in the following forms and strengths:1

  • 10 milligrams (mg) oral capsule
  • 18 milligrams (mg) oral capsule
  • 25 milligrams (mg) oral capsule
  • 40 milligrams (mg) oral capsule
  • 60 milligrams (mg) oral capsule
  • 80 milligrams (mg) oral capsule
  • 100 milligrams (mg) oral capsule

Take medications, like Strattera, as prescribed by your provider to get the most benefit to treat ADHD symptoms. Taking medications as prescribed can help avoid unintended effects that can potentially be harmful or deadly.

Strattera Dosage for Adults with Attention-Deficit Hyperactivity Disorder (ADHD)

Strattera is commonly used as an FDA-approved medication for treating ADHD in children, adolescents, and adults. Children and adults have different starting and target doses. No dose adjustment is needed for older adults. Significant ADHD symptom improvement in adults can be seen after two weeks of starting Strattera.1, 4

Here is Strattera dosage information for treatment for adult ADHD:1, 4

  • Typical starting dosage: When starting Strattera in adults, the initial dose is 40 mg per day.
  • Dosage increases: After taking the typical starting dose for 3 days, your provider may increase your dose to 80 mg per day. This 80 mg can either be taken once daily or divided twice daily.
  • Maximum dosage:  After two to four weeks of being on the increased dose, your doctor may decide to increase to a recommended maximum dose of 100 mg per day.

Strattera Dosage for Children & Adolescents With ADHD

Strattera is also an FDA-approved treatment for ADHD in children and ADHD in adolescents that are age 6 and older. Dosing in children and adolescents is based on body weight and can be given once daily or in two divided doses, once in the morning and once in the late afternoon or early evening. It may take up to a week to start noticing improvements in ADHD symptoms.1, 5

Here is Strattera dosage information for ADHD in children and adolescents:1

  • Typical starting dosage: For children and adolescents weighing 70 kg (about 154 pounds) or less, Strattera is started at 0.5 mg/kg. For children and adolescents weighing more than 154 pounds, Strattera is started at 40 mg per day.
  • Dosage increases:  In children and adolescents weighing 154 pounds or less, after taking the starting dose for at least 3 days the provider may increase the dose. In children and adolescents weighing more than 154 pounds, the provider may increase the dose to 80 mg once daily or 40mg twice daily.
  • Maximum dosage: In children and adolescents weighing 154 pounds or less, the maximum dose is 1.4 mg/kg or 100 mg, whichever is lower. The maximum dose for children and adults over 154 pounds is 100 mg.

Strattera Dosing Considerations

Initial and target doses should be half the normal dose in patients with moderate liver impairment or one-quarter of normal doses in severe liver impairment. Your prescriber will likely discontinue Strattera if you have jaundice or severe liver injury.

How to Take Strattera

Strattera is only supplied as an oral immediate-release (IR) capsule in the US. It can be taken with or without food. Its contents can irritate the eyes, so it should not be opened, crushed, or chewed. If a patient cannot swallow it and another medication cannot be chosen, a compounding pharmacy could prepare an alternative formulation (e.g. liquid).1

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What to Do if I Miss a Dose of Strattera?

Some patients may stop using Strattera once they start feeling better. Some patients may stop using Strattera when they experience side effects from the drug. Once your body gets used to Strattera, some initial effects will be less severe or may completely disappear.

It is important to continue the medication despite these effects. Abruptly discontinuing Strattera can disrupt the stabilization of brain chemicals and lead to additional or worsening ADHD symptoms. Regular communication with healthcare professionals is recommended to address concerns, fine-tune the dosage, and ensure the best treatment outcomes.1

Strattera’s duration of action is up to 24 hours. A missed dose could result in the return of ADHD symptoms until the next dose is taken. If enough doses are missed, it could take more time to become effective again.1, 6, 7, 8

Strattera Withdrawal

Withdrawal is very rarely observed clinically and the drug can be safely discontinued in this case.

Symptoms of withdrawal from Strattera include:1

  • Decreased heart rate
  • Low blood pressure
  • Inability to regulate temperature.

Can You Overdose on Strattera?

Yes, you can overdose on Strattera. Patients have reported seizures due to Strattera overdose. The potential for severe liver injury may exist for some people taking Strattera. The medication should be discontinued in patients who develop jaundice (yellowish appearance of the skin and the whites of the eyes) or liver injury.1, 9

Signs of an overdose on Strattera include:1, 9, 10, 11

  • Increased heart rate
  • Increased blood pressure
  • Headache
  • Agitation
  • Nausea/vomiting
  • Rash
  • Tremor
  • Drowsiness/dizziness
  • Seizure

What Should You Do If You Take Too Much Strattera?

If an overdose is suspected, call 1(800) 222-1222 for specific guidance from Poison Control.

Seek emergency medical attention for a potential Strattera overdose if:12

  • Too much Strattera was taken on purpose
  • Any overdose symptoms are present
  • The person is unable to estimate the amount of Strattera taken (dose is unknown)
  • The amount ingested is more than 100mg or more than 2 capsules at once

Questions to Ask Your Health Team About Strattera Dosage

In the case of an emergency, call 911. The toll-free Poison Help line (1-800-222-1222) connects you to your local poison center to speak with a poison expert immediately. This expert can advise you on first aid and may save you from visiting the emergency room if an overdose is suspected.

Questions to ask your care team about Strattera dosages include:

  • Is it safe to take Strattera with my other medications?
  • Will Strattera be covered by my insurance?
  • Does my medical history indicate a need to adjust my dosage?
  • How long will it take before my symptoms improve?
  • Should I let my therapist know I am taking this medication?
  • What should I do if I want to stop taking Strattera?
  • What is the recommended starting dosage for Strattera?
  • How often should I take the medication, and at what time of day?
  • Are there any specific instructions for taking Strattera with or without food?
  • How will my dosage be adjusted over time, if necessary?
  • Are there any factors that may require a higher or lower dosage than usual?
  • Are there any specific symptoms or side effects that may indicate the need for a dosage adjustment?
  • How long should I stay on a particular dosage before evaluating its effectiveness?
  • What should I do if I accidentally miss a dose of Strattera?
  • Can I adjust my dosage on my own, or should I always consult with my healthcare provider first?
  • How do I compare different ADHD medications, such as Qelbree vs Strattera?
  • Are there any lifestyle or dietary factors that may interact with the effectiveness of Strattera or its dosage?

In My Experience

In my experience, Strattera has been a good treatment option for my patients with ADHD. It’s important to talk to your provider about this topic and follow their guidance on treatment. Strattera is not in the stimulant class like other ADHD medications, so it is a good option to ask your provider if you cannot tolerate the side effects of ADHD stimulant medications (e.g. inability to sleep, loss of appetite), like Adderall and Ritalin.

It may take some time to find the most effective dose for your symptoms, so it is also important to be patient and communicate well with your prescriber. Your provider, psychiatrist, and pharmacist can be great resources to help you find the ADHD medication and dose that is the right fit for you.

Pamela Wiltfang, PharmD, MPH, BA, CHES headshot Pamela Wiltfang, PharmD, MPH
Sources

ChoosingTherapy.com strives to provide our readers with mental health content that is accurate and actionable. We have high standards for what can be cited within our articles. Acceptable sources include government agencies, universities and colleges, scholarly journals, industry and professional associations, and other high-integrity sources of mental health journalism. Learn more by reviewing our full editorial policy.

  • DailyMed. (2022). STRATTERA- atomoxetine hydrochloride capsule. NIH.gov. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm

  • Adler, L. A., Liebowitz, M., Kronenberger, W., Qiao, M., Rubin, R., Hollandbeck, M., Deldar, A., Schuh, K., & Durell, T. (2009). Atomoxetine treatment in adults with attention-deficit/hyperactivity disorder and comorbid social anxiety disorder. Depression and anxiety, 26(3), 212–221. Retrieved from https://doi-org/10.1002/da.20549

  • Sumner, C. R., Schuh, K. J., Sutton, V. K., Lipetz, R., & Kelsey, D. K. (2006). Placebo-controlled study of the effects of atomoxetine on bladder control in children with nocturnal enuresis. Journal of child and adolescent psychopharmacology, 16(6), 699–711. Retrieved from https://doi.org/10.1089/cap.2006.16.699

  • Spencer, T., Biederman, J., Wilens, T., Prince, J., Hatch, M., Jones, J., Harding, M., Faraone, S. V., & Seidman, L. (1998). Effectiveness and tolerability of tomoxetine in adults with attention deficit hyperactivity disorder. The American journal of psychiatry, 155(5), 693–695. Retrieved from https://doi-org/10.1176/ajp.155.5.693

  • Spencer, T., Biederman, J., Heiligenstein, J., Wilens, T., Faries, D., Prince, J., Faraone, S. V., Rea, J., Witcher, J., & Zervas, S. (2001). An open-label, dose-ranging study of atomoxetine in children with attention deficit hyperactivity disorder. Journal of child and adolescent psychopharmacology, 11(3), 251–265. Retrieved from https://doi-org/10.1089/10445460152595577

  • Jain, R., Jain, S., & Montano, C. B. (2017). Addressing Diagnosis and Treatment Gaps in Adults With Attention-Deficit/Hyperactivity Disorder. The primary care companion for CNS disorders, 19(5), 17nr02153. Retrieved from https://doi.org/10.4088/PCC.17nr02153

  • Subcommittee on Attention-Deficit/Hyperactivity Disorder, Steering Committee on Quality Improvement and Management, Wolraich, M., Brown, L., Brown, R. T., DuPaul, G., Earls, M., Feldman, H. M., Ganiats, T. G., Kaplanek, B., Meyer, B., Perrin, J., Pierce, K., Reiff, M., Stein, M. T., & Visser, S. (2011). ADHD: clinical practice guideline for the diagnosis, evaluation, and treatment of attention-deficit/hyperactivity disorder in children and adolescents. Pediatrics, 128(5), 1007–1022. Retrieved from https://doi.org/10.1542/peds.2011-2654

  • Volkow, N. D., & Swanson, J. M. (2013). Clinical practice: Adult attention deficit-hyperactivity disorder. The New England journal of medicine, 369(20), 1935–1944. Retrieved from https://doi.org/10.1056/NEJMcp1212625

  • Stojanovski, S. D., Robinson, R. F., Baker, S. D., Casavant, M. J., Hayes, J. R., & Nahata, M. C. (2006). Children and adolescent exposures to atomoxetine hydrochloride reported to a poison control center. Clinical toxicology (Philadelphia, Pa.), 44(3), 243–247. Retrieved from https://doi.org/10.1080/15563650600584311

  • Lovecchio, F., & Kashani, J. (2006). Isolated atomoxetine (Strattera) ingestions commonly result in toxicity. The Journal of emergency medicine, 31(3), 267–268. Retrieved from https://doi.org/10.1016/j.jemermed.2005.12.024

  • Spiller, H. A., Hays, H. L., & Aleguas, A., Jr (2013). Overdose of drugs for attention-deficit hyperactivity disorder: clinical presentation, mechanisms of toxicity, and management. CNS drugs, 27(7), 531–543. Retrieved from https://doi.org/10.1007/s40263-013-0084-8

  • Forrester M. B. (2006). Adult atomoxetine ingestions reported to Texas Poison Control Centers, 2003-2005. The Annals of pharmacotherapy, 40(12), 2136–2141. Retrieved from https://doi.org/10.1345/aph.1H430

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