- On October 19, 2026, no discount card priced Zepbound below Lilly’s own routes. Optum Perks showed about $1,100 for four single-dose pens, close to Lilly’s $1,086.37 list price.
- Commercial insurance that covers the single-dose pen: start with Lilly’s savings card, as little as $25 a fill. Uninsured, or insured without Zepbound coverage: start with LillyDirect. It costs $299 (2.5 mg), $399 (5 mg) or $449 (7.5 to 15 mg, refilled within 45 days) a month.
- Medicare Part D members who qualify for the Medicare GLP-1 Bridge pay a $50 copay. Lilly’s cards can’t be combined with any discount card.
Eli Lilly sells Zepbound, its once-weekly tirzepatide injection, as single-dose pens, single-dose vials and a four-dose KwikPen. It is FDA-approved, with diet and exercise, for weight reduction in adults with obesity or overweight and a related health condition. It is also approved, with diet and exercise, for moderate to severe obstructive sleep apnea in adults with obesity.1 A prescription discount card is a free coupon that can lower a drug’s cash price when you use it in place of insurance. ChoosingTherapy.com’s partner Optum Perks is one of these cards, accepted at over 64,000 pharmacies. Optum Perks prices only the single-dose pen, and Lilly’s lowest cash prices are for vials and the KwikPen through LillyDirect.
Request a Zepbound KwikPen prescription through Optum Perks Online Care
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Quick picks by coverage
None of the discount cards checked priced Zepbound below Lilly’s own programs.
- Commercial plan that covers Zepbound: Lilly’s savings card, from $25 a fill.
- Commercial plan that excludes it, or no insurance: LillyDirect self-pay, $299 to $449 a month with on-time refills.
- Medicare Part D, weight management: the GLP-1 Bridge, a $50 copay.
- No prescriber yet: Optum Perks Online Care, a $39 request; its menu lists the Zepbound KwikPen.
- A 2.5 mg KwikPen at a local chain: RxSaver, which matched Lilly’s $299.
Zepbound prices on each card and Lilly route
Prices were checked October 19, 2026. GoodRx blocked access, so its price is from a June 6, 2026, archive. Prices vary by location.
|
Route |
Form and quantity |
Price |
Where |
|
Lilly savings card, plan covers pen |
Single-dose pens, 1 to 3 months |
From $25 |
Your pharmacy |
|
Lilly savings card, plan excludes pen |
4 single-dose pens |
From $499 |
Your pharmacy |
|
LillyDirect self-pay |
4 vials or 1 KwikPen |
$299 to $449; up to $699 if late |
Delivery or Walmart pickup |
|
Medicare GLP-1 Bridge |
KwikPen |
$50 copay |
Eligible Part D members |
|
RxSaver |
1 KwikPen, 2.5 mg |
$299.00 |
Walgreens, CVS, Costco and others, ZIP 21114 |
|
SingleCare |
1 KwikPen, 2.5 mg |
$490.02 (Kroger) to $528.94 (Costco), with signup |
ZIP 23666 |
|
GoodRx (June 6) |
4 pens, 2.5 mg |
$995.00 |
CVS, Walgreens, Walmart, ZIP 20149 |
|
WellRx |
4 pens, 2.5 mg |
$1,044.15 to $1,167.24 |
ZIP 77381 |
|
Optum Perks |
4 pens, 2.5 mg |
About $1,100 |
Walgreens, CVS, Walmart, no ZIP |
|
Hippo |
4 pens, any strength |
$1,122.06 to $1,155.20 |
National estimate |
|
BuzzRx |
8 pens, 5 mg |
$1,589.11 to $2,270.55 |
No location |
|
Cost Plus Drugs |
Not sold |
n/a |
n/a |
|
Lilly list price |
4 single-dose pens |
$1,086.37 |
As of January 2026, |
Your prescriber chooses the dose. Lilly lists 2.5 mg as a starting dose that isn’t approved for maintenance.
This article is for information only and is not medical advice. Talk to a doctor or licensed clinician before starting, stopping, or changing any treatment.
Lilly’s Zepbound savings card with commercial insurance
Lilly’s savings card is for people with commercial drug insurance. You pay as little as $25 for a one-, two- or three-month fill if your plan covers the single-dose pen. Savings are capped at $100 per month of supply and $1,300 a year, up to 13 fills.2 The terms say savings end on December 31, 2026.
Lilly’s savings card brings a month of pens down to as low as $499 if your plan doesn’t cover the single-dose pen. The card matches LillyDirect’s $299, $399 and $449 prices for plans that don’t cover the KwikPen, up to 11 fills a year.
The savings card requires you to be 18 or older and live in the US or Puerto Rico. Anyone on Medicare, Medicaid, TRICARE, the VA or another government program is excluded. So are plans in alternate funding programs.2
GoodRx research reported by NPR found 12 million people lost Zepbound coverage from 2025 to 2026. The same research found 88% of people with GLP-1 coverage face some restriction. KFF found the share of employers not covering obesity drugs rose from 52% in 2024 to 57% in 2025.3
LillyDirect self-pay vials and KwikPens
LillyDirect is Lilly’s own pharmacy. Its self-pay prices apply to a box of four single-dose vials or one KwikPen holding four weekly doses. Both cost $299 a month at 2.5 mg and $399 at 5 mg. Higher strengths cost $449 if you refill within 45 days of your last delivery. Later refills cost $499 (7.5 mg) or $699 (10 to 15 mg).4
Your prescriber sends the prescription to LillyDirect, which delivers free or offers pickup at Walmart Pharmacy. Vials are sold only through LillyDirect. Both forms need needles bought separately.
Lilly cut LillyDirect’s vial prices to the current tiers in December 2025. Late-refill prices have since fallen from as much as $1,049 to $699. The KwikPen, FDA-approved in February 2026, matches the vial prices. TrumpRx.gov lists Zepbound at $299, the 2.5 mg price.
Lilly’s KwikPen card at a retail pharmacy
Lilly’s KwikPen Self-Pay Savings Card gives cash buyers the same $299 to $449 prices at a retail pharmacy, with no insurance needed. You agree not to bill an insurer or government program for the purchase. The savings may not apply at the register. You may need to file a claim, due by March 31, 2027.2
Zepbound with Medicare and the GLP-1 Bridge
The Medicare GLP-1 Bridge is a CMS program covering certain GLP-1 drugs for eligible Part D members. It runs from July 1, 2026, through December 31, 2027. Members pay a $50 copay and the Part D deductible doesn’t apply. The copay doesn’t count toward out-of-pocket costs.5 Lilly says the Bridge covers the Zepbound KwikPen for weight management.
Lilly says CMS requires you to be 18 or older, with Part D coverage and a prescription for weight management. Your BMI must be 35 or higher, or 27 or higher with certain weight-related conditions. Prior authorization is required and some plan types, including PACE, are excluded. People with moderate to severe sleep apnea aren’t eligible. Lilly says their regular Part D plan may already cover that use.6
The Commonwealth Fund notes that Part D members can’t use online discounts with their drug coverage. Those purchases don’t count toward the Part D out-of-pocket limit.7
Can you use Optum Perks for Zepbound?
You can use Optum Perks for Zepbound, but its card price is near Lilly’s list price. On October 19, 2026, it showed about $1,100 for four 2.5 mg single-dose pens at Walgreens, CVS, Target (CVS) and Walmart. Optum Perks lists only the single-dose pen, so it can’t match LillyDirect’s $299 to $449 KwikPen and vial tiers.8
The Optum Perks card is free and has no eligibility requirements. Its coupons can’t be used with insurance copays or benefits. Card spending doesn’t count toward your deductible.
Optum Perks Online Care offers a $39 prescription request that needs no appointment or membership. Its GLP-1 menu lists only the Zepbound KwikPen. The fee covers the visit only; any prescription can be filled at the pharmacy of your choice. Online Care accepts insurance but doesn’t require it. The fee is HSA and FSA eligible.9
Start a $39 Optum Perks Online Care request
See is Optum Perks legit for ownership and Optum Perks vs GoodRx for other drugs.
GoodRx coupons for Zepbound
GoodRx’s Zepbound coupon price is close to Lilly’s $1,086.37 list price. Its June 6, 2026, archive showed $995.00 for four 2.5 mg pens at CVS, Walgreens and Walmart near ZIP 20149. A banner beside the price advertised Lilly’s $299 KwikPen.
GoodRx coupons replace insurance on a fill and can’t be used with Medicare or Medicaid. The amount you pay isn’t applied to your deductible automatically, though many plans accept receipts for possible credit.
SingleCare, RxSaver and other discount cards
SingleCare and RxSaver price the KwikPen. Hippo, WellRx and BuzzRx price single-dose pens, and Cost Plus Drugs doesn’t sell Zepbound.
SingleCare
SingleCare priced one 2.5 mg KwikPen at $490.02 at Kroger and Harris Teeter near ZIP 23666, with free signup. That’s about $191 more than Lilly’s $299. Costco’s signup price was $528.94. SingleCare replaces insurance or Medicare on a fill and can’t be combined with either.
RxSaver
RxSaver estimated $299.00 for one 2.5 mg KwikPen near ZIP 21114 at Walgreens, CVS, Walmart, Costco, Safeway and others. That equals Lilly’s 2.5 mg price. Its coupons can’t be used with commercial plans, Medicare or Medicaid.
Hippo
Hippo estimated four single-dose pens at $1,122.06 at CVS to $1,155.20 at Albertsons, for every strength. It also lists retail vial prices. Lilly sells vials only through LillyDirect, so those quotes likely can’t be filled.
WellRx and BuzzRx
WellRx showed $1,044.15 at Claya, an online pharmacy, for four 2.5 mg pens near ZIP 77381. Its top listing was a $149 compounded GLP-1, which isn’t Zepbound or FDA-approved.10 BuzzRx listed eight 5 mg pens from $1,589.11 at Walgreens, roughly $795 per four.
Cost Plus Drugs
Mark Cuban Cost Plus Drugs doesn’t sell Zepbound; its catalog search found nothing on October 19, 2026.
Can you combine a discount card with the Zepbound savings card?
You can’t combine a discount card with the Zepbound savings card. Lilly’s terms bar using its cards with any other discount card, coupon or similar Zepbound offer.2
Optum Perks, GoodRx, SingleCare, Hippo and RxSaver each replace insurance on a given fill. Card and Lilly self-pay spending doesn’t count toward your deductible automatically. Under Lilly’s self-pay card terms, you agree not to apply that spending to your deductible.
When a discount card suits Zepbound buyers
RxSaver’s $299 suits 2.5 mg KwikPen buyers at chains other than Walmart. LillyDirect offers pickup at Walmart. RxSaver also needs no claim, which Lilly’s KwikPen card may require. Without insurance, BuzzRx had the lowest single-dose pen price of the cards checked at roughly $795 per four 5 mg pens at Walgreens. LillyDirect’s 5 mg vial or KwikPen costs $399.
Without a prescriber, Optum Perks’ $39 Online Care request can get you a KwikPen prescription filled at Lilly’s self-pay price.
Frequently Asked Questions
How much is Zepbound without insurance?
Zepbound without insurance costs $299 to $699 a month through LillyDirect, depending on strength and refill timing. Four single-dose pens on discount cards ran from roughly $795 (BuzzRx) to $1,167.24 (WellRx).
Does the Zepbound savings card work with Medicare?
The Zepbound savings card for commercial insurance doesn’t work with Medicare or other government coverage.2 Part D members may qualify for the GLP-1 Bridge at $50. Lilly’s KwikPen self-pay card has no government-program exclusion, though you can’t bill Medicare for it.
Is there a generic Zepbound?
There is no generic Zepbound. Optum Perks notes it’s a brand-name drug, so copays can run higher than for a generic.8 The Zepbound guide explains how it works, and the Mounjaro coupon guide covers Mounjaro savings.
Is Zepbound HSA or FSA eligible?
Zepbound from LillyDirect may be HSA or FSA eligible, depending on your plan. Lilly’s commercial card bars claiming the savings amount from either account.
Why do Zepbound prices differ by discount card site?
Zepbound prices differ by discount card site because each site quotes different pharmacies, ZIP codes and forms. BuzzRx says its prices change and suggests checking close to the day you fill.
Can you use a discount card if insurance doesn’t cover Zepbound?
You can use a discount card if insurance doesn’t cover Zepbound, paying the card’s price in place of your plan. LillyDirect’s vial and KwikPen start at $299, and no card checked went lower than that.
Does the Zepbound savings card expire?
The Zepbound savings card expires on December 31, 2026, under Lilly’s terms. The KwikPen self-pay card ends the same day, with claims due by March 31, 2027.2
ChoosingTherapy.com strives to provide our readers with mental health content that is accurate and actionable. We have high standards for what can be cited within our articles. Acceptable sources include government agencies, universities and colleges, scholarly journals, industry and professional associations, and other high-integrity sources of mental health journalism. Learn more by reviewing our full editorial policy.
- Eli Lilly and Company. (August 2026). Zepbound prescribing information. Retrieved from: https://pi.lilly.com/us/zepbound-uspi.pdf
- Eli Lilly and Company. (2026). Zepbound coverage and savings, terms and conditions. Retrieved from: https://zepbound.lilly.com/coverage-savings
- NPR. (April 2026). Health insurance coverage for Wegovy and Zepbound. Retrieved from: https://www.npr.org/2026/04/22/nx-s1-5794613/health-insurance-wegovy-zepbound
- Eli Lilly and Company. (October 2026). LillyDirect: Zepbound. Retrieved from: https://lillydirect.lilly.com/pharmacy/zepbound
- Centers for Medicare & Medicaid Services. (July 2026). Medicare GLP-1 Bridge. Retrieved from: https://www.cms.gov/medicare/coverage/prescription-drug-coverage/medicare-glp-1-bridge
- Eli Lilly and Company. (June 2026). What Medicare Part D patients need to know about accessing Foundayo and Zepbound. Retrieved from: https://investor.lilly.com/news-releases/news-release-details/what-medicare-part-d-patients-need-know-about-accessing-foundayo
- Faith Leonard and Gretchen Jacobson, The Commonwealth Fund. (October 2024). Are Online Discount Websites Helping Medicare Beneficiaries? Retrieved from: https://www.commonwealthfund.org/blog/2024/are-online-discount-websites-helping-medicare-beneficiaries
- Optum Perks. (October 2026). Zepbound coupons and prices. Retrieved from: https://perks.optum.com/drug/zepbound
- Optum Perks. (October 2026). Online Care: GLP-1. Retrieved from: https://perks.optum.com/online-care/glp-1
- U.S. Food and Drug Administration. (2026). FDA’s concerns with unapproved GLP-1 drugs used for weight loss. Retrieved from: https://www.fda.gov/drugs/drug-alerts-and-statements/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss
- Eli Lilly and Company. (June 2026). Zepbound pricing information. Retrieved from: https://pricinginfo.lilly.com/zepbound
We regularly update the articles on ChoosingTherapy.com to ensure we continue to reflect scientific consensus on the topics we cover, to incorporate new research into our articles, and to better answer our audience’s questions. When our content undergoes a significant revision, we summarize the changes that were made and the date on which they occurred. We also record the authors and medical reviewers who contributed to previous versions of the article. Read more about our editorial policies here.
Author: Adrienne Santos-Longhurst
Reviewer: MD review pending