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  • Can You Die From Stress?Can You Die From Stress?
  • The Body's Reaction to StressThe Body's Reaction to Stress
  • Complications of Chronic StressComplications of Chronic Stress
  • When Stress Becomes HarmfulWhen Stress Becomes Harmful
  • When to Seek HelpWhen to Seek Help
  • Treatment OptionsTreatment Options
  • Coping With StressCoping With Stress
  • In My ExperienceIn My Experience
  • InfographicsInfographics
  • Additional ResourcesAdditional Resources
Stress Articles Stress Therapy for Stress Stress Management Types of Stress

Can Stress Kill You?

Tanya J. Peterson, NCC, DAIS

Author: Tanya J. Peterson, NCC, DAIS

Headshot of Naveed Saleh MD, MS

Medical Reviewer: Naveed Saleh, MD, MS Licensed medical reviewer

Headshot of Naveed Saleh MD, MS

Naveed Saleh MD, MS

Dr. Saleh is an experienced physician and a leading voice in medical journalism. His contributions to evidence-based mental health sites have helped raise awareness and reduce stigma associated with mental health disorders.

See My Bio Editorial Policy
Published: November 3, 2023
  • Can You Die From Stress?Can You Die From Stress?
  • The Body's Reaction to StressThe Body's Reaction to Stress
  • Complications of Chronic StressComplications of Chronic Stress
  • When Stress Becomes HarmfulWhen Stress Becomes Harmful
  • When to Seek HelpWhen to Seek Help
  • Treatment OptionsTreatment Options
  • Coping With StressCoping With Stress
  • In My ExperienceIn My Experience
  • InfographicsInfographics
  • Additional ResourcesAdditional Resources
Headshot of Tanya Peterson, NCC
Written by:

Tanya J. Peterson

NCC
Headshot of Naveed Saleh, MD, MS
Reviewed by:

Naveed Saleh

MD, MS

Many people are aware that stress is bad for physical and mental health–but can stress kill you? While stress does not kill you, prolonged exposure can lead to health conditions and death in extreme cases. Early intervention and stress management can reduce the risk of long-term complications like cardiovascular disease, digestive problems, and respiratory problems.

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Can You Die From Stress?

Stress does not kill you. Complications are minimal when our bodily reactions to stress and anxiety are time-limited, and the brain and body can return to baseline functioning.1 However, chronic stress can lead to possibly fatal illnesses.

How the Body Responds to Chronic Stress

As mentioned, dying from stress is highly unlikely. However, stressful thoughts, emotions, or situations activate reactions throughout the brain and body in a rapid-fire chain involving the nervous and endocrine systems.2,3,4,5,6,7

Experiencing an emotional event (internal or external) causes the hypothalamus to react to and help solve the problem. The hypothalamus alerts the pituitary gland of the threat via corticotropin-releasing hormone (CRH; also known as CRF for “factor”), ultimately leading to the release of stress hormones from the adrenal glands. Cortisol and adrenaline flow through the bloodstream into every system and cell.

In turn, the fight-or-flight response causes reactions and changes throughout the body to combat the stressor. The body does not differentiate between types of stress but just reacts.

Bodily reactions to stress include:1,7

  • Pupils dilate for sharper vision
  • Heart rate and blood pressure increase to boost circulation away from internal organs and toward extremities
  • Breathing becomes rapid and shallow to give the brain and body oxygen
  • Muscles tense for increased strength and reaction time
  • Platelets increase to allow for quicker blood clotting in case of physical injury
  • The immune system increases white blood cell counts and promotes inflammation in preparation for healing
  • Carbohydrates and fat stores break down to immediately increase blood sugar (glucose) and lipid levels for energy

Complications of Chronic Stress

Determining how much stress can kill you is impossible, but extended periods of distress without opportunities for recovery are harmful. Cortisol levels remain high when perceived threats chronically or frequently activate the fight-or-flight stress reaction. Such responses accelerate aging and damage tissues in every organ, gland, and system in your body.2,3

Cardiovascular Disease & Stress

Stress and heart disease are strongly connected.8 Increased heart rate and blood pressure impact small blood vessels throughout the brain and body, causing inflammation and plaque deposits.2 This change increases the risk of heart attack, stroke, and even heart disease.3

Stress & Respiratory Diseases

Stress impacts inflammation of tissue, breathing rate, and blood flow to the lungs. Prolonged stress can worsen problems like asthma and emphysema, making them more difficult to manage.4,5

Immune System Problems & Stress

Stress initially enhances the immune system but can also shut down the system when chronic. For instance, you might notice you are sick more often when stressed.2,4,5 Constant off-again, on-again stress reactions leave the body confused and trick the immune system into overactivity, thus contributing to autoimmune diseases.2

Stress & Digestive Disorders

The digestive system also reacts to chronic stress responses. Stress hormones and immune system behavior lead to inflammation, affecting how your entire digestive system functions.4,5 Related disorders include acid reflux, irritable bowel syndrome, inflammatory bowel diseases, and functional disorders like gastroparesis.9

Musculoskeletal Problems & Stress

Prolonged muscle tension can cause chronic headaches and back, shoulder, neck, and joint pain.3 Chronic pain can become debilitating.

Stress & Type 2 Diabetes

Stress eating can contribute to weight gain associated with type 2 diabetes (T2D). You could crave fatty, sugary food when stressed for a reason. As part of the stress response, the liver produces and releases extra glucose to provide energy. When under chronic stress, your body needs a steady supply of fats and sugars, so you crave these foods. Both what you eat and bodily reactions may lead to T2D.4,5,7

Cancer & Stress

The causes of cancer are complex. Experts know little about the direct influence of stress in the development of cancer, but research suggests a link. For example, some evidence found a connection between chronic immune system activation and tumors.1

How Can You Tell When Stress Is Harmful?

Stress itself is neither inherently good nor bad. We feel stress because our brains and bodies respond to anything that disrupts our emotional or physiological balance.(FN2) Positive stress (eustress) can be helpful, increasing motivation and energy so we can respond to problems and enjoy pleasant experiences.5

Chronic, extended, continual, and erratic fight-or-flight activation is what becomes harmful. Stress attacks us on multiple fronts, impacting the body and brain, the mind, and our behavior.

Therefore, tuning in to these experiences can help you identify harmful stress. For example, experiencing new or exacerbated physical or mental health symptoms may indicate that stress is taking a toll on your well-being. In these cases, stress management can help you improve your mood, emotions, or physical health.

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When to Get Professional Help for Stress

Professional support can be essential when dealing with life, especially if you constantly think, “Stress is killing me.” Sometimes, life stressors remain overwhelming no matter how many stress management techniques you try on your own.

Stress can cause many challenges, including anxiety, a lack of motivation, and even suicidal thoughts. Reaching out for help can improve your life when stress becomes a deeper problem than a minor inconvenience or passing difficulty. Finding a therapist can seem daunting, but you can ask your friends, family members, faith leaders, or doctor for recommendations. You can also use an online therapist directory to locate a licensed professional in your area who is a good fit for you.

How to Treat Chronic & Unhealthy Stress

Stress will not kill you, and the good news is that many treatment options are available to help you cope with life stressors. You cannot control automatic processes in your brain and body, but you are also not at the mercy of these physiological responses. Therapy, medication, and lifestyle changes can treat stress and associated challenges you may face.

Therapy

Therapy for stress can help you address a wide range of associated concerns. A therapist can help you identify underlying factors that may be contributing to an unhealthy reaction to stressors. You can then problem-solve with your therapist to create goals and action steps to move past these unhelpful life situations, whether from the past or present. Therapy can also help you with anxiety, depression, and unhealthy habits exacerbate stress.3,4,5

Medication

While stress is not a medical condition, medication is often necessary to treat resulting physical or mental health problems. For example, medication can help balance blood pressure and blood sugar levels.

Stress and anxiety are closely related, and prescribers may recommend anxiety medications for those struggling with both issues.8 Psychopharmacology approaches are best when paired with therapy and lifestyle changes.

How to Cope With Stress

Lifestyle changes go beyond stress management. Practices like exercise, social support, and engaging in hobbies help train your automatic reaction to stress. Additionally, eliminating unhealthy and damaging habits, such as smoking, unhealthy eating, or substance use, can also benefit your overall well-being.8

Believe it or not, you can affect the workings of your nervous system by doing activities that help the parasympathetic nervous system (PNS) remain active and dominant, even in the face of stress. Breathwork, mindfulness, meditation, and relaxation techniques are especially useful.

You can learn these techniques via self-help books, dedicated courses, or therapy. However, you do not have to make immediate and sweeping changes to your lifestyle. Identify one unhealthy habit to eliminate and replace with a positive alternative. Then, take small steps to work toward a better relationship with stress.

In My Experience

Tanya J. Peterson, NCC, DAIS Tanya J. Peterson, NCC, DAIS
“Stress is a universal human experience, and you are not alone in your struggles. While stress is difficult and can wreak havoc on your health, you don’t have to resign to life-threatening problems or a life of misery. Reaching out to a friend or family member for support and working with a therapist can make a positive difference in your life and well-being.”

Can Stress Kill You Infographics

Can You Die From Stress? Complications of Stress Coping With Stress

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Sources Update History

ChoosingTherapy.com strives to provide our readers with mental health content that is accurate and actionable. We have high standards for what can be cited within our articles. Acceptable sources include government agencies, universities and colleges, scholarly journals, industry and professional associations, and other high-integrity sources of mental health journalism. Learn more by reviewing our full editorial policy.

  • American Institute of Stress. (n.d.). Stress and cancer. Retrieved from https://www.stress.org/stress-and-cancer

  • American Psychological Association. (2022). How stress affects your health. Retrieved from https://www.apa.org/topics/stress/health

  • American Institute of Stress. (2010, November). Can stress kill you? Retrieved from https://www.stress.org/can-stress-kill-you

  • American Institute of Stress. (n.d.). Stress effects. Retrieved from https://www.stress.org/stress-effects#body

  • American Institute of Stress. (n.d.). Proof. Retrieved from https://www.stress.org/proof

  • Mayo Clinic Staff. (2019, March). Chronic stress puts your health at risk. Retrieved from https://www.mayoclinic.org/healthy-lifestyle/stress-management/in-depth/stress/art-20046037

  • American Institute of Stress. (n.d.). Mismatched: Your Brain Under Stress. Retrieved from https://www.stress.org/mismatched-your-brain-under-stress

  • American Heart Association. (n.d.). Stress and heart health. Retrieved from https://www.heart.org/en/healthy-living/healthy-lifestyle/stress-management/stress-and-heart-health

  • Mayer, E.A. (2000). The neurobiology of stress and gastrointestinal disease. Gut, 47(6): 861-869.

  • SimplePractice. (2018). Psychotherapy session rates by state and city: 2018. Retrieved from https://www.simplepractice.com/blog/median-therapy-session-rates-by-state-and-city-cpt-codes/

Show more Click here to open the article sources container.

We regularly update the articles on ChoosingTherapy.com to ensure we continue to reflect scientific consensus on the topics we cover, to incorporate new research into our articles, and to better answer our audience’s questions. When our content undergoes a significant revision, we summarize the changes that were made and the date on which they occurred. We also record the authors and medical reviewers who contributed to previous versions of the article. Read more about our editorial policies here.

November 3, 2023
Author: No Change
Reviewer: No Change
Primary Changes: Edited for readability and clarity. Reviewed and added relevant resources.
June 8, 2021
Author: Tanya Peterson, NCC, DAIS
Reviewer: Naveed Saleh, MD, MS
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