Endogenous & Exogenous Depression: Definition, Symptoms, & Treatment
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The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder (2014, May). BMC Medicine. Retrieved from: https://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-12-73.
The doctrine of the two depressions in historical perspective (2007). Acta Psychiatrica Scandinavica. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712975/.
Endogenous Depression (1998). Comprehensive Clinical Psychology. Retrieved from: https://www.sciencedirect.com/topics/medicine-and-dentistry/endogenous-depression
Mental Health Disorder Statistics (2022). John Hopkins Medicine. Retrieved from: https://www.hopkinsmedicine.org/health/wellness-and-prevention/mental-health-disorder-statistics
Depression: major depressive disorder (2018, February). Mayo Clinic. Retrieved from: https://www.mayoclinic.org/diseases-conditions/depression/symptoms-causes/syc-20356007.
Are you thinking about suicide? How to stay safe and find treatment (2018, January). Mayo Clinic. Retrieved from: https://www.mayoclinic.org/diseases-conditions/suicide/in-depth/suicide/art-20048230.
Nurtured by nature (2020, April). American Psychological Association. Retrieved from: https://www.apa.org/monitor/2020/04/nurtured-nature.
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Author: No Change
Reviewer: No Change
Primary Changes: Updated for readability and clarity. Reviewed and added relevant resources. Added “What Is Depression?”, “Causes of Endogenous Depression”, and “Diagnosis of Endogenous Vs. Exogenous Depression”. New material written by Silvi Saxena, MBA, MSW, LSW, CCTP, OSW-C and reviewed by Dena Westphalen, PharmD.
Author: Nicole Arzt, LMFT
Reviewer: Rajy Abulhosn, MD