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  • Do I Need Cobenfy?Do I Need Cobenfy?
  • How to GetHow to Get
  • Cost of CobenfyCost of Cobenfy
    • Cobenfy PricesCobenfy Prices
  • Who Is Cobenfy For?Who Is Cobenfy For?
  • Who Shouldn't Take Cobenfy?Who Shouldn't Take Cobenfy?
  • Cobenfy Alternatives Cobenfy Alternatives
  • Questions to AskQuestions to Ask
  • Prescriber's TipsPrescriber's Tips
  • Additional ResourcesAdditional Resources

How to Get Cobenfy Prescribed

Pamela Wiltfang, PharmD, MPH, BA, CHES headshot

Author: Pamela Wiltfang, PharmD, MPH

Pamela Wiltfang, PharmD, MPH, BA, CHES headshot

Pamela Wiltfang PharmD, MPH, CHES, CHW

With 12+ years of experience, Pamela Wiltfang is an accomplished pharmacist with a focus on medication therapy management. Pamela has expertise in psychotropic meds, weight loss, sexual health, and sleep medication management.

See My Bio Editorial Policy
Published: January 24, 2025
  • Do I Need Cobenfy?Do I Need Cobenfy?
  • How to GetHow to Get
  • Cost of CobenfyCost of Cobenfy
    • Cobenfy PricesCobenfy Prices
  • Who Is Cobenfy For?Who Is Cobenfy For?
  • Who Shouldn't Take Cobenfy?Who Shouldn't Take Cobenfy?
  • Cobenfy Alternatives Cobenfy Alternatives
  • Questions to AskQuestions to Ask
  • Prescriber's TipsPrescriber's Tips
  • Additional ResourcesAdditional Resources
Brand name:
Cobenfy
Generic name:
None
Class of drug:
Muscarinic Agonist
FDA-approved treatments:
Schizophrenia
Common Off-label Uses (non-FDA approved):
None
Common alternatives:

Abilify, Latuda, Vraylar

View Drug Class, FDA-Approved Uses, Off-Label Uses, and more

*An off-label use of a medication is a use that is not FDA-approved. Prescribers can decide to use a medication off-label because, in their professional judgment, they believe it may offer a benefit to someone.

To get prescribed Cobenfy online, start by finding an online psychiatry provider for an evaluation. For an in-person assessment, your primary care physician may refer you to a prescriber who may offer a Cobenfy prescription.

Your primary care provider may be able to refer you to a prescriber who can evaluate you and prescribe Cobenfy. If you are looking for online access to your prescription, we have thoroughly evaluated, such as Lifestance Health. If your provider feels this medication is a good fit for your schizophrenia symptoms, they may prescribe you Cobenfy online.

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Key takeaways

  • To get prescribed Cobenfy online, start by getting an evaluation from an online provider who can evaluate your symptoms.

  • Cobenfy alternatives may be necessary for some to consider, including typical and atypical antipsychotics.

  • Brand name Cobenfy for schizophrenia symptoms can cost $1,850 for a 30-day supply of the smallest dosage available without insurance. Cobenfy savings programs and discounts may all help lower costs.1, 2, 3

Do I Need a Cobenfy Prescription?

To get a prescription for Cobenfy, you will first need a thorough evaluation from a licensed healthcare provider specializing in psychiatric conditions. This assessment will help determine if Cobenfy is the right treatment option for your symptoms. Cobenfy’s active ingredients, xanomeline and trospium chloride, work together to manage both the positive and negative symptoms of schizophrenia by targeting specific neurotransmitters in the brain. Cobenfy is a new type of antipsychotic medication called a muscarinic agonist. As an FDA-approved treatment for schizophrenia in adults, Cobenfy provides an effective option for those seeking to manage their condition.1

Some signs that you may benefit from a Cobenfy prescription include to following symptoms of schizophrenia:2

  • Hallucinations: Sensory experiences that differ from reality from any sense, including sights, sounds, and smells
  • Delusions: False ideas that can be bizarre or non-bizarre
  • Disorganized speech patterns and behavior
  • Lack of pleasure
  • Flat or blunted emotions
  • Social withdrawal

You provider will also consider these factors before prescribing Cobenfy:

  • Any previous antipsychotics you have tried
  • If you have a  history of liver problems or urinary retention
  • If you have a history of allergic reaction to either of the active ingredients, xanomeline or trospium chloride

How to Get a Prescription for Cobenfy Online & In Person

To get prescribed Cobenfy for schizophrenia, you will first need an evaluation. Your provider will determine whether Cobenfy is a good fit for treating your symptoms. The process of getting a diagnosis and potentially prescribed Cobenfy online or in person may vary for people of different ages.

It is important to find an online provider who can prescribe antipsychotic medications like Cobenfy. For in-person prescription options, a good place to start is with your primary care provider.

How to Get a Cobenfy Prescription Online

Here is how to get Cobenfy prescribed to you online in six steps.

Step 1: Book an Appointment With an Online Psychiatry Provider

The first step is to book an appointment with an online provider that can prescribe antipsychotic medications like Cobenfy, such as Lifestance Health. We have thoroughly reviewed this platform, and in using the services ourselves, we have found it to be a good place to get started with an evaluation.

Step 2: Get a Psychiatric Evaluation & Discuss Your Symptoms

Your provider will evaluate your overall health history, your mental health symptoms, and any treatments you may have tried in the past. They may also speak with others you interact with regularly, such as family members. This is important because you may show symptoms differently in various settings. This discussion will help the provider know whether Cobenfy may be safe and appropriate for you.

Step 3: Get Treatment Recommendations

Your provider will develop a treatment plan to help improve your symptoms and quality of life. They may recommend behavioral therapy or medication such as Cobenfy, or possibly both. If Cobenfy looks like it could help you, your provider will discuss the risks, benefits, and how to take the medication.

Step 4: Fill Your Online Cobenfy Prescription

If offered, your prescriber will give you a prescription, which you may fill through their online platform. You may be able to get Cobenfy medication delivered to your home, but it can vary widely depending on the state you live in. All online psychiatric platforms will deliver prescriptions to a local pharmacy.

Step 5: Schedule Follow-up Appointments

If prescribed Cobenfy, your doctor will recommend regular follow-up appointments to monitor your symptoms and potential side effects, adjusting your medication as needed.

Step 6 : Discuss Prescription Refills With Your Provider

Talk to your prescriber about how frequently you may refill your Cobenfy medication. This timeframe may depend on how well you respond to the medication, if you experience side effects, or if you may need to consider another medication. It may also depend on how the platform manages medication delivery, such as offering 90-day supplies.

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How to Get a Cobenfy Prescription In Person

In five steps, here is how to get Cobenfy prescribed to you in person.

Step 1: Book an Appointment With a Psychiatric Provider

A good place to start for an in-person psychiatric evaluation is with your primary care provider. This may be a physician, nurse practitioner, or physician assistant. If they determine it is needed, they can refer you or your child to a specialist, such as a psychiatrist. They can further evaluate whether to include Cobenfy as a part of the treatment plan for you.

Step 2: Get an Evaluation & Discuss Your Symptoms

Your provider will evaluate your overall health history, your mental health symptoms, and any treatments you may have tried in the past. They may also speak with others you interact with regularly, such as family members. This is important because you may show symptoms differently in various settings. This discussion will help the provider know whether Cobenfy may be safe and appropriate for you.

Step 3: Get Treatment Recommendations

Your provider will develop a treatment plan to help improve your symptoms and quality of life. They may recommend behavioral therapy or medication such as Cobenfy, or possibly both. If Cobenfy looks like it could help you, your provider will discuss the risks, benefits, and how to take the medication.

Step 4: Choose Where to Get Your Cobenfy Prescription Filled

If offered, your prescriber will give you a prescription that you may fill at your preferred local pharmacy or an online platform. You may be able to get Cobenfy delivered to your home, but it can vary widely depending on the state you live in. All online psychiatry platforms will deliver prescriptions to a local pharmacy.

Step 5: Schedule Follow-up Appointments

If prescribed Cobenfy, your doctor will recommend regular follow-up appointments to monitor your symptoms and potential side effects, adjusting your medication as needed.

How Much Does Cobenfy Cost?

Several factors impact the cost of Cobenfy, including your choice of pharmacy, any available discounts or savings programs, and the specific Cobenfy dosage prescribed by your healthcare professional. Using a prescription savings program may reduce costs for those who are eligible.

Cobenfy Prices

The cost of Cobenfy currently ranges from $909-$1050 for a 30-day supply of 50 milligrams/20mg without insurance. Your Cobenfy prescription may cost much less with insurance depending on your plan and coverage. The cost of Cobenfy will also vary based on the dosage and amount prescribed. Discounts for Cobenfy may be available and may reduce your out of pocket costs.

Note: Cash prices listed are derived from multiple sources. The prices listed are an estimate only and cannot be guaranteed. For exact prices, please contact the pharmacy.

PHARMACY COST
Walmart
$987
Walgreens
$975
CVS / Target
$953
RiteAid
$929
Kroger
$909
Costco
$1050
Hy-Vee
$934
Publix
$982
Albertsons
$942

Does Insurance Cover Cobenfy?

Your insurance plan may cover your prescription for Cobenfy, depending on the company. However, insurance policies can change coverage at any time. Requirements for medication coverage may also vary for Medicare, Medicaid, TRICARE, and commercial insurance policies. Contact your insurance provider directly to learn whether your prescription may be covered.

LifeStance Health accepts many insurance plans and offers a wide variety of services including neuropsychological testing.

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Who Is Cobenfy a Good Fit For?

An evaluation from a medical provider can determine whether getting a Cobenfy prescription may be helpful treatment for you. Cobenfy is thought to work by affecting the activity of certain brain chemicals to improve all types of schizophrenia symptoms.

Cobenfy has two active ingredients, xanomeline and tropism chloride, and is FDA-approved for treating schizophrenia in adults and there are currently no off-label (non-FDA-approved) uses for the medication.1

Who Should Not Take Cobenfy?

Every person is different, and while Cobenfy is an FDA-approved treatment for schizophrenia, it may not be the right medication for everyone. Cobenfy has been shown to be safe and effective for adults, but there are some exceptions to consider.

People who should take extra caution before using Cobenfy include:1

  • Pregnant and breastfeeding parents
  • Children
  • Adults over 65 years of age
  • Those with kidney problems
  • Those with liver problems
  • Those with narrow-angle glaucoma

This may not be a complete list of who should have caution before taking Cobenfy. Discuss with your healthcare provider to see if Cobenfy is right for you.

Cobenfy Alternatives

For some individuals, Cobenfy alternatives may need to be considered. It may take several weeks before you feel the full effects of Cobenfy. Everyone responds in a unique way to medication, and your age, health history, and previous experience with side effects can have an impact.

LifeStance Health is a reliable online provider that offers Cobenfy alternatives. Both typical and atypical antipsychotic can help reduce symptoms of psychosis, and some are more suitable for certain conditions than others. The potential risks and benefits of each medication varies.

Other atypical antipsychotics are usually the first medications considered as Cobenfy alternatives because of their safety and effectiveness. These medications are newer and offer fewer side effects and less frequent dosing schedules. Still, they require close monitoring throughout therapy.

Typical antipsychotic medications are also known as first-generation antipsychotics. These medications usually come with a risk of more severe side effects that need to be monitored. Additionally, typical antipsychotics often need to be taken multiple times per day.

Generic Cobenfy

There is no generic version of Cobenfy available at this time.

Over-the-Counter Cobenfy Options

There are several over-the-counter Cobenfy alternatives, such as supplements and vitamins, that claim to help with the treatment of schizophrenia symptoms. However, none of these are FDA-approved treatments. Quality studies are limited and have yet to show that such treatments improve symptoms of schizophrenia.

Some of these treatments can also interact with other medications you may be taking. Check with reputable sources and your healthcare providers before taking any supplements.

While over-the-counter options cannot replace Cobenfy, some non-medication approaches may be beneficial additions to your treatment plan. Placing focus on regular exercise, a balanced diet, and improving sleep hygiene can support mental health and overall wellbeing.

Abilify

Drug class: Atypical Antipsychotic

Used for
  • FDA-approved for schizophrenia, bipolar disorder, depression, irritability with autism, Tourette syndrome
  • Common off-label uses: Anxiety, OCD, PTSD

$578

Lowest price
View Prices
Or learn more

Risperdal

Drug class: Atypical Antipsychotic

Used for
  • FDA-approved for schizophrenia, bipolar mania, irritability associated with autism
  • Common off-label uses: Tourette syndrome

$145

Lowest price
View Prices
Or learn more

Haloperidol

Drug class: Typical antipsychotic

Used for
  • FDA-approved for psychotic disorders, Tourette disorder, severe behavior problems in children
  • Common off-label uses: Agitation, mania

$6

Lowest price
View Prices
Or learn more

Chlorpromazine

Drug class: Antipsychotic

Used for
  • FDA-approved for psychotic disorders, schizophrenia, behavioral problems in children, mania
  • Common off-label uses: Delirium, anxiety, insomnia, migraines

$21

Lowest price
View Prices
Or learn more

Loxapine

Drug class: Antipsychotic

Used for
  • FDA-approved for schizophrenia
  • Common off-label uses: Anxiety, personality disorders, PTSD

$13

Lowest price
View Prices
Or learn more

Latuda

Drug class: Atypical Antipsychotic

Used for
  • FDA-approved for schizophrenia, depression episodes with bipolar
  • Common off-label uses: Anxiety, mania and irritability, anger in with autism

$1379

Lowest price
View Prices
Or learn more

Zyprexa

Drug class: Atypical Antipsychotic

Used for
  • FDA-approved for schizophrenia, bipolar disorder
  • Common off-label uses: Depression, anorexia nervosa, agitation during intoxication

$440

Lowest price
View Prices
Or learn more

Seroquel

Drug class: Atypical Antipsychotic

Used for
  • FDA-approved for schizophrenia, bipolar disorder
  • Common off-label uses: Insomnia, dementia, personality disorders

$124

Lowest price
View Prices
Or learn more

Rexulti

Drug class: Atypical Antipsychotic

Used for
  • FDA-approved for secondary schizophrenia treatment, depression, agitation with Alzheimer's disease
  • Common off-label uses: Bipolar disorder

$1469

Lowest price
View Prices
Or learn more
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Questions to Ask Your Provider

If you believe getting a Cobenfy prescription may be helpful for your treatment plan, one place to start is by talking to your primary healthcare provider. They know your health history and may be able to prescribe medication for your condition, if needed. Cobenfy is FDA-approved for treating schizophrenia in adults.

And if they think a specialist would be helpful, such as a psychiatrist, they may make a referral. Alternatively, if you do not have a primary healthcare provider, an online psychiatry provider is a good place to start.

To prepare for your first appointment, collect important information about your condition. Write down your main symptoms, how they affect your daily life, and what good symptom relief would look like. Describe your treatment goals as well as your questions and concerns about using medications.

Questions to ask your care team about getting a Cobenfy prescription include:

  • How often should I come for checkups for my Cobenfy prescription?
  • Is there a certain medication that is best for treating the schizophrenia symptoms I experience?
  • What common side effects will I likely experience when I start my Cobenfy medication?
  • How long will Cobenfy’s side effects last?
  • What should I do if Cobenfy does not work for me?
  • What will happen if I stop Cobenfy abruptly?
  • What should I do if I miss a dose of Cobenfy?
  • How long does Cobenfy take to show its effectiveness?
  • What are the precautions I must take with Cobenfy during treatment?
  • Are there any foods, drinks, or supplements I should avoid while taking Cobenfy?

Prescriber’s Tips

Your prescriber will share important information about your Cobenfy prescription. They will explain how to take and store your medication, what to avoid when taking it, and what to do about side effects. Follow these tips for safe and effective use of Cobenfy.

  • Take Cobenfy exactly as prescribed by your doctor at the same time every day without changing the dose or frequency. Since this medication acts by balancing brain chemicals, changes in dosage can result in reduced efficacy or increase in side effects.
  • Remain patient as your body adjusts to your new dose of Cobenfy. It may take up to several weeks to see full benefits. You may experience unwanted side effects such as nausea or dizziness as your body adjusts to the medication.
  • Since Cobenfy is a newly approved medication, report any unusual side effects to your doctor, as this feedback helps gather information about how patients respond to Cobenfy in real-life settings.
  • Take Cobenfy 1 hour before or 2 hours after a meal. Taking Cobenfy with a high or low fat meal can reduce the effectiveness of medication in the system.
Pamela Wiltfang, PharmD, MPH, BA, CHES headshot Pamela Wiltfang, PharmD, MPH

Frequently Asked Questions

What Is Cobenfy?

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Xanomeline and trospium chloride are the active ingredients in brand name Cobenfy, a medication in the muscarinic agonist drug family. It is an antipsychotic medication that is FDA-approved for the treatment of schizophrenia in adults.1

How Does Cobenfy Work?

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Symptoms of schizophrenia may occur when certain receptors in the brain have too many or too few chemical messengers. Cobenfy works by activating muscarinic receptors in the brain to help adjust the levels of important chemical messengers that may be involved in schizophrenia.1

Who Can Prescribe Cobenfy?

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Antidepressants, such as Cobenfy, can be prescribed by a licensed healthcare provider. These providers may be primary care physicians, psychiatrists, nurse practitioners, or physician assistants.

Where Can I Get Cobenfy?

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You can get your prescription filled either at a local pharmacy or by an online provider who can prescribe antidepressants, such as LifeStance Health.

Can You Get Cobenfy Prescription Refills Online?

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You may be able to get Cobenfy refills online. Talk to your provider to make sure you can get your prescription refills when you need them, whether in person or online.

Can I Get Cobenfy Delivered to My Home?

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You may be able to get your Cobenfy prescription delivered to your home, but may vary depending on the state you live in. All online psychiatry platforms will deliver prescriptions to a local pharmacy.

Can You Get Cobenfy From a Walk-in Clinic?

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Urgent care clinics cannot prescribe Cobenfy, antipsychotics, or other medications typically used to treat schizophrenia. If you have a Cobenfy prescription already, contact your primary provider or local pharmacy for help. If you do not have a prescription, you will need a full psychiatric evaluation first. Providers at an urgent care or walk-in clinic are not able to provide this type of evaluation.4

How Much Does Cobenfy Cost Without Insurance?

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Cobenfy list price without insurance is currently $1,850 for a 30-day supply of the smallest dosage available (20 mg).

Can You Get Cobenfy Over the Counter?

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No, Cobenfy is only available with a prescription.

Is There a Generic Version of Cobenfy?

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No, a generic version of Cobenfy is not available at this time.

Sources

ChoosingTherapy.com strives to provide our readers with mental health content that is accurate and actionable. We have high standards for what can be cited within our articles. Acceptable sources include government agencies, universities and colleges, scholarly journals, industry and professional associations, and other high-integrity sources of mental health journalism. Learn more by reviewing our full editorial policy.

  • Cobenfy. (2024). Prescribing information. Retrieved from https://packageinserts.bms.com/pi/pi_cobenfy.pdf

  • American Psychiatric Association. (2022). Diagnostic and statistical manual of mental disorders (5th ed., text rev.). Arlington, VA: American Psychiatric Publishing.

  • Cobenfy. (n.d.). Coverage and support program. Retrieved November 17, 2024, from https://www.cobenfy.com/support-program/coverage

  • Spencer, Aiden. (May 19, 2016). What Type of Medication Can an Urgent Care Doctor Prescribe? AJMC.com. Retrieved from https://www.ajmc.com/view/what-type-of-medication-can-an-urgent-care-doctor-prescribe

Show more Click here to open the article sources container.

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To help our readers take the next step in their mental health journey, ChoosingTherapy.com has partnered with leaders in mental health and wellness. ChoosingTherapy.com is compensated for marketing by the companies included below.

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