Cymbalta is a medication prescribed for the treatment of depression and anxiety, as well as for other medical conditions in some cases. Cymbalta may result in side effects ranging from mild to severe, so it’s important to discuss these with your doctor. Only licensed medical professionals can prescribe Cymbalta. However, this may be done both in-person and via telepsychiatry. You and your doctor can determine if Cymbalta is a good option for you.
What Is Cymbalta (Duloxetine)?
Cymbalta, sold under the generic name duloxetine, is an FDA-approved medication for treating major depressive and generalized anxiety disorders.1 Both generic duloxetine and brand name Cymbalta work the same.
Cymbalta belongs to the serotonin and norepinephrine reuptake inhibitor (SNRI) class of drugs. The medication works by preventing the reuptake of serotonin and norepinephrine in the brain, thus improving one’s overall mood and emotional state. SNRIs work similarly to SSRIs. However, while SNRIs block the reabsorption of both norepinephrine and serotonin, SSRIs only block serotonin.
Cymbalta is FDA-approved for the treatment of:1
- Major depressive disorder (MDD) in adults
- Generalized anxiety disorder (GAD) in adults and children 7 years of age and older
- Diabetic peripheral neuropathic pain in adults
- Fibromyalgia in adults and children 13 years of age and older
- Chronic musculoskeletal pain in adults
In some cases, Cymbalta may be prescribed off-label (not FDA approved) for treating chemotherapy-induced neuropathy or stress urinary incontinence.3
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Side Effects of Cymbalta
Cymbalta commonly results in mild side effects, such as nausea and vomiting. Reactions to the medication occur as a person’s body adjusts to the presence of Cymbalta. Typically, it takes between two and four weeks for Cymbalata to improve symptoms of depression or anxiety.3
Side effects of Cymbalta may include:1
- Headaches
- Nausea
- Sleepiness
- Diarrhea
- Dry mouth
- Appetite issues
- Sexual dysfunction
- Constipation
- Sweating
- Dizziness
Drug Interactions With Cymbalta
Cymbalta interaction with other medications or substances can be dangerous, possibly leading to overdose and sudden death. Discuss any medications or supplements with your doctor before starting Cymbalta in order to understand these associated risks.
Substances that may interact with Cymbalta include:1
- Adderall
- St. John’s Wort
- Non-Steroidal anti-inflammatory drugs (NSAIDs)
- Other SRNIs
- MAOI inhibitors
- Pimozide
- Migraine drugs
- Benzodiazepines
- Alcohol
- Blood thinners
- Thioridazine
Do I Need a Cymbalta Prescription?
Before providing a Cymbalta prescription, your doctor will determine if it is a suitable option for you. Cymbalta and psychotherapy are both effective at relieving symptoms of depression and anxiety. However, your physician may recommend adding Cymbalta as a part of your treatment plan if you are not benefiting from therapy.
You may benefit from a Cymbalta prescription if you experience:
- Mood swings
- Concentration difficulties
- Irritability
- Appetite issues
- Feelings of sadness
- Loss of interest
- Sleep problems
How to Get a Cymbalta Prescription
Only registered doctors can prescribe Cymbalta. Before considering this medication, be sure to inform your physician of any symptoms you are experiencing, as well as previous histories of other mental and physical conditions.
When looking to get prescribed Cymbalta, be sure to follow these steps:
- Make an appointment with your physician: Before a prescription can be issued, an appointment with a licensed physician must be made and attended.
- Talk with your provider about your condition: Be sure to inform your doctor about any and all of your symptoms. This will help them determine the best course of action.
- Receive a diagnosis: Upon reviewing your symptoms, a doctor can provide you with an accurate diagnosis, inform you of treatment options, and offer tips for coping.
- Consider costs and insurance coverage: Cymbalta medication can be costly, especially if you do not have insurance. Consider your options before fulfilling your prescription.
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Who Can Prescribe Cymbalta?
The FDA regulates Cymbalta prescriptions in order to prevent misuse and prescribing faults. Because of this, only licensed medical practitioners, such as registered nurses or psychiatrists, can prescribe Cymbalta.
Professionals who can prescribe Cymbalta include:4
- Clinical psychologists
- Registered nurse practitioners
- Registered physician assistants
- Psychiatrists
- Primary care providers
How to Get a Cymbalta Prescription Online
Telepsychiatry has become a suitable solution for receiving online treatment. Like traditional therapy, online physiatry offers screening, assessments, prescriptions, medication refills, and mental health consultations.
Online psychiatry can be beneficial for those who have busy schedules or live in areas without mental health resources. Also, telepsychiatry is often more cost friendly than in-person therapy. However, this depends on your treatment or insurance plan.
What If I Can’t Get Prescribed Cymbalta?
If you fail to receive a Cymbalta prescription, don’t worry. Your doctor can recommend an alternative better suited for you. Avoid doctor shopping or seeking a prescription from another provider. Do not ask family members or friends for Cymbalta, as taking this medication without proper guidance can be dangerous.
Alternatives to Cymbalta include:
Do Over the Counter Alternatives Exist?
There are over-the-counter (OTC) alternatives that may help relieve mild symptoms. These substances, including natural remedies and supplements, may be effective for some users. However, practice cautious when seeking alternatives. Consult with your doctor to understand the associated risks of any treatment option.
Common OTC alternatives include:
- Vitamin D
- Fish oil
- Methylfolate
- St. John’s Wort
Questions to Ask Your Health Team
Always consult your doctor about safe medication practices before starting a prescription. Furthermore, inform your doctor of any substances or other medications you are currently taking or considering. Asking the right questions can help limit or prevent the risk of experiencing side effects.
Questions to ask your care team include:
- What are the best online psychiatry options?
- Are there Cymbalta alternatives?
- Can I switch medications if Cymbalta does not work for me?
- Is it safe to use over-the-counter medications while taking Cymbalta?
- How long will Cymbalta’s side effects last?
- What happens if I mix Cymbalta with another substance?
When to Seek Immediate Medical Help
Combining Cymbalta with another substance can result in an overdose, which can be life-threatening. If you have overdosed on Cymbalta or are experiencing an allergic reaction, call 9-1-1 or seek medical assistance immediately.
Final Thoughts
Cymbalta is effective in improving symptoms of depression and anxiety. Taking the medication can result in side effects that can become severe, depending on your age and overall health. However, your prescriber can determine if Cymbalta is a suitable medication for you.
Additional Resources
To help our readers take the next step in their mental health journey, Choosing Therapy has partnered with leaders in mental health and wellness. Choosing Therapy is compensated for marketing by the companies included below.
Virtual Psychiatry
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For Further Reading
Cymbalta for Anxiety: Effectiveness, Dosage, & More
Cymbalta Weight Gain: Everything You Need to Know
Cymbalta & Alcohol: Understanding the Risks
Cymbalta (Duloxetine) Withdrawal: Symptoms, Duration, & How to Cope
Cymbalta (Duloxetine) Sexual Side Effects: What They Are & How to Manage Them
Celexa Vs. Cymbalta: Differences, Similarities, & Which to Take
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