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  • Cost Without InsuranceCost Without Insurance
    • Zoloft PricesZoloft Prices
  • Cost With InsuranceCost With Insurance
  • Coupons & Discount CardsCoupons & Discount Cards
  • Cost Savings ProgramsCost Savings Programs
  • Other Ways to Save MoneyOther Ways to Save Money
  • How to GetHow to Get
  • Zoloft AlternativesZoloft Alternatives
  • Prescriber's TipsPrescriber's Tips
  • Additional ResourcesAdditional Resources

Zoloft (Sertraline) Cost, Coupons, Savings Tips, & More

Baron Miller PharmD headshot

Author: Baron Miller, PharmD

Baron Miller PharmD headshot

Baron Miler PharmD

Baron Miller is an experienced pharmacist and is an expert in medication counseling. His areas of focus include ADHD, depression, eating disorders, addiction, and working with LGBTQ youth.

See My Bio Editorial Policy
Headshot of Heidi Moawad, MD

Medical Reviewer: Heidi Moawad, MD Licensed medical reviewer

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Heidi Moawad MD

Heidi Moawad, MD is a neurologist with 20+ years of experience focusing on
mental health disorders, behavioral health issues, neurological disease, migraines, pain, stroke, cognitive impairment, multiple sclerosis, and more.

See My Bio Editorial Policy
Published: February 21, 2025
  • Cost Without InsuranceCost Without Insurance
    • Zoloft PricesZoloft Prices
  • Cost With InsuranceCost With Insurance
  • Coupons & Discount CardsCoupons & Discount Cards
  • Cost Savings ProgramsCost Savings Programs
  • Other Ways to Save MoneyOther Ways to Save Money
  • How to GetHow to Get
  • Zoloft AlternativesZoloft Alternatives
  • Prescriber's TipsPrescriber's Tips
  • Additional ResourcesAdditional Resources
Brand name:
Zoloft
Generic name:
Sertraline Hydrochloride
Is the generic available:
Yes
Class of drug:
SSRI
Boxed warning:
Yes
FDA-approved treatments:
Major Depression, OCD, Panic Disorder, PTSD, Social Anxiety Disorder, Premenstrual Dysphoric Disorder (PMDD)
Common Off-label Uses (non-FDA approved):
Bulimia Nervosa, Premature Ejaculation
Common alternatives:

Celexa, Lexapro, Prozac

View Drug Class, FDA-Approved Uses, Off-Label Uses, and more

*An off-label use of a medication is a use that is not FDA-approved. Prescribers can decide to use a medication off-label because, in their professional judgment, they believe it may offer a benefit to someone.

The price of Zoloft can be reduced by using coupons, savings cards, and other discounts. Without insurance, the cost of Zoloft is about $426-$527 for a 30-day supply of the smallest dosage. The cost of sertraline, the generic form of Zoloft, is typically much lower than the brand name medication. Other ways to decrease the cost of Zoloft include checking non-retail/local pharmacy prices, contacting your insurance carrier, and using online coupons. Using a mail-order pharmacy and getting a 90-day supply can also lower the price of your Zoloft prescription.

If you’re considering Zoloft, online psychiatry platforms can be a good place to start. Talkiatry works with many major insurance plans and Brightside Health takes cash payments. Both platforms can connect you with a provider quickly for psychiatric assessments and prescription consultation.

Boxed Warning: Sertraline (Zoloft) – Risk of suicidal thoughts and behaviors in certain people

Click here to open and close the box warning container.

Sertraline, the active ingredient in Zoloft, has a black box warning. These are the most serious types of warnings from the Food and Drug Administration (FDA). Sertraline can increase the risk of suicidal thoughts and behaviors in children, adolescents, and young adults. Regardless of your age, you should talk with your doctor about serious risks with sertraline and any other medications before starting treatment.

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Online Psychiatry and Medication Management Covered by Insurance

Talkiatry can match you with a real psychiatrist who takes your insurance and is seeing new patients. They’re in-network with major insurers and offer medication management. Get started with a short online assessment

Visit Talkiatry

How Much Is Zoloft Without Insurance?

The cost of Zoloft without insurance depends on factors such as dosage strength, frequency, the quantity prescribed by your provider, and your location.

Zoloft Prices

The cost of Zoloft currently ranges from $426-$527 for a 30-day supply of 25 milligrams without insurance. Your Zoloft prescription may cost much less with insurance depending on your plan and coverage. A similar prescription of the generic form of Zoloft, sertraline hydrochloride, costs $7-$24. The cost of Zoloft will also vary based on the dosage and amount prescribed. Coupons for Zoloft are often available and may reduce your out of pocket costs.

Note: Cash prices listed are derived from multiple sources. The prices listed are an estimate only and cannot be guaranteed. For exact prices, please contact the pharmacy.

PHARMACY COST
Walmart
$444
Walgreens
$449
CVS / Target
$475
RiteAid
$453
Kroger
$446
Costco
$527
Hy-Vee
$426
Publix
$484
Albertsons
$482

How Much Does Zoloft Cost With Insurance?

The cost of Zoloft with health insurance depends on your specific coverage. Insurance companies may offer different copayments or coinsurance rates for Zoloft. Consult with your insurance provider to understand your out-of-pocket expenses for Zoloft under your specific health insurance plan.

Commercial Insurance

The cost of Zoloft with insurance can vary depending on copayments, deductibles, and coinsurance rates. Some plans may even provide discounts or preferred pricing for certain medications. Your insurance company may offer other benefits and savings, such as using mail-order pharmacy options or prescription savings programs. For individuals with commercial insurance, contact your insurance provider directly to learn about specific qualifications and coverage details for Zoloft.

Medicare

In general, Medicare plans do not cover brand name Zoloft, but do cover the generic version. Be aware that coverage may change, so it’s important to check your Medicare plan before filling your prescription.1

Medicaid

Zoloft is classified as a non-preferred drug under Medicaid, which means less expensive alternatives on the list may be chosen first. Prior authorization is necessary before filling this prescription. With prior approval, Medicaid may provide coverage for Zoloft.2 Contact your local Medicaid office or review your plan documents to understand the specific terms of coverage for your prescription.

TRICARE

If you are covered by TRICARE, check directly with your TRICARE plan for the specific details regarding Zoloft coverage. TRICARE typically provides coverage for all available forms of sertraline. Depending on your coverage, the generic version may be either required or preferred over brand name Zoloft. Additionally, some plans may require preauthorization for certain medications, including Zoloft.3

Zoloft Coupons, Savings Cards, & Discounts

There are many ways to save money when looking for a Zoloft prescription. To decrease out-of-pocket costs, you can look at what insurance covers, uses of coupons/rebates, and patient assistance programs. Zoloft coupons and discount cards may be available from either the manufacturer’s website or alternative cost-saving websites.

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Online Psychiatry and Medication Management Covered by Insurance

Talkiatry can match you with a real psychiatrist who takes your insurance and is seeing new patients. They’re in-network with major insurers and offer medication management. Get started with a short online assessment

Visit Talkiatry

Zoloft Cost Savings Programs

Trintellix cost savings programs are available from organizations such as RxAssist, NeedyMeds, and savings from the manufacturer. Some organizations provide information about cost savings programs. Others assist with the application and enrollment process. Individuals need to apply for each program and meet certain criteria to qualify for savings.

Zoloft Discount Card

A Zoloft discount card is available on the manufacturer’s website. This savings card is valued at $150 per use or the amount of your insurance co-pay, whichever is less. Individuals must meet all criteria to be eligible for the discount. This savings card cannot be used with benefits from enrolled in Medicare, Medicaid, or another state or federal healthcare program. Be sure to read all rules and limitations for using this savings card on the manufacturer’s website.4

RxAssist

RxAssist is an online patient assistance resource center. This website has information about patient assistance and savings programs for prescription medications such as Zoloft. RxAssist has a search feature where you can enter the name of a medication and find available savings programs and discounts. At this time, RxAssist displays discounts for sertraline but not for brand name Zoloft. Information is constantly updated and patients are encouraged to check back frequently for the latest information.5

NeedyMeds

NeedyMeds is a nonprofit organization dedicated to helping individuals with limited financial resources have access to prescription medications, such as Lexapro. To be eligible for their assistance program, consider the following criteria:6

  • Your income falls at or below 500% of the federal poverty level.
  • You are a US resident.
  • Please check if you have Part D prescription coverage, and if you do, reach out to NeedyMeds Customer Support to apply for eligibility.

Other Ways to Find Zoloft Coupons & Discount Cards

Zoloft discount cards and savings offers are available online, at pharmacies, and via the mail. These and other options may help save money when filling your prescription for Zoloft.

Pharmacy Discounts and Savings Cards

Pharmacy discounts and savings cards for Zoloft and sertraline are available. Many pharmacies offer their own savings programs or discount cards, which can be found on their official websites or in-store. These programs often provide discounts on a range of prescription medications, including Zoloft. Patients can typically download these cards online or request them directly from the pharmacy.

Online Resources and Apps

Numerous online resources, websites, and mobile apps offer convenient ways to save on your Zoloft prescription. Websites like GoodRx, RxSaver, and SingleCare provide users with easy access to Zoloft coupons. You can compare prices at different pharmacies and choose the most cost-effective option. These platforms often feature user-friendly interfaces, enabling individuals to simply enter their prescription details and receive a list of available discounts.

HSA Accounts

A health savings account (HSA) is a part of high-deductible health insurance plans. With an HSA, you can set aside pre-tax money from your paycheck to pay for certain health expenses. This means the money you contribute to this account is not subject to federal taxes, leaving the full amount available for use. Contact your company directly to learn if your Zoloft prescription is eligible.7

Ask Your Prescriber for Samples

Your prescriber may have samples of Zoloft available. Samples provide a small supply of the medication, allowing you to try it without the expense of a full prescription.

Ask About Getting a 90-day Supply

If you and your prescriber determine that Zoloft is suitable for you, getting a 90-day supply can save money. Refilling every three months is often less expensive and more convenient than refilling every month. This also lessens the chance of running out before a refill is needed. Mail-order pharmacies typically offer 90-day supplies to cut down on the cost of shipping and operating local pharmacies.

Fill Your Prescription by Mail-order

Using a mail-order pharmacy is another way to get your medication at a lower price. Your provider calls in the prescription directly and your medication is typically delivered to your home within two weeks. Mail-order prescriptions are ideal for medications that are not temperature sensitive and are used as long-term treatments.8

How to Get a Zoloft Prescription

To get a prescription for Zoloft, you will first need a psychiatric evaluation. Start by consulting your primary provider, who may be a physician, nurse practitioner, or physician assistant. They may refer you to a psychiatrist to further evaluate your depression symptoms. A provider doing an evaluation will consider your medical history, any medications or substances you are using, and other factors. With this information, they will then determine whether Zoloft is a suitable treatment for you.

To get prescribed Zoloft online, you will also start by getting evaluated by an online psychiatric provider. We have thoroughly reviewed platforms like Talkiatry or Circle Medical that prescribe antidepressants like Zoloft, and found them each to be a good place to get started with an evaluation. If your provider feels Zoloft is a good fit for your depression symptoms, they may offer you an online prescription for the medication.

ADVERTISEMENT

Online Psychiatry and Medication Management Covered by Insurance

Talkiatry can match you with a real psychiatrist who takes your insurance and is seeing new patients. They’re in-network with major insurers and offer medication management. Get started with a short online assessment

Visit Talkiatry

Zoloft Alternatives

For some individuals, Zoloft alternatives may need to be considered. It may take several weeks before you feel the full effects of antidepressant medication like Zoloft. Everyone responds in a unique way to medication, and your age, health history, and previous experience with side effects can have an impact. Your doctor will help to decide which medication may work best for you.

Zoloft

Drug class: SSRI

Used for
  • FDA-approved medication for depression, OCD, panic disorder, PTSD, social anxiety disorder, premenstrual dysphoric disorder (PMDD)
  • Common off-label uses: Bulimia nervosa, premature ejaculation

$426

Lowest price
View prices
Or learn more

Sertraline Hydrochloride

Drug class: SSRI

Used for
  • FDA-approved medication for depression, OCD, panic disorder, PTSD, social anxiety disorder, premenstrual dysphoric disorder (PMDD)
  • Common off-label uses: Bulimia nervosa, premature ejaculation

$7

Lowest price
View prices
Or learn more

Celexa

Drug class: SSRI

Used for
  • FDA-approved medication for depression
  • Common off-label uses: Generalized anxiety disorder, OCD, panic disorder, premenstrual dysphoric disorder (PMDD), social anxiety disorder, PTSD

$274

Lowest price
View prices
Or learn more

Lexapro

Drug class: SSRI

Used for
  • FDA-approved medication for depression, anxiety
  • Common off-label uses: OCD, PTSD, premenstrual dysphoric disorder (PMDD), panic disorder, bulimia nervosa, binge eating disorder

$440

Lowest price
View prices
Or learn more

Prozac

Drug class: SSRI

Used for
  • FDA-approved medication for depression, OCD, bulimia nervosa, panic disorder
  • Common off-label uses: Body dysmorphic disorder, generalized anxiety disorder, social anxiety disorder, PTSD, disruptive mood dysregulation disorder, borderline personality disorder, specific phobias

$427

Lowest price
View Prices
Or learn more

Wellbutrin SR

Drug class: Atypical Antidepressant

Used for
  • FDA-approved medication for major depressive disorder
  • Common off-label uses: ADHD, bipolar disorder, aid to smoking cessation

$227

Lowest price
View Prices
Or learn more

Cymbalta

Drug class: SNRI

Used for
  • FDA-approved medication for depression, anxiety, diabetic neuropathy, fibromyalgia, musculoskeletal pain
  • Common off-label uses: Chemotherapy-induced peripheral neuropathy, stress urinary incontinence, osteoarthritic pain

$257

Lowest price
View prices
Or learn more
Click here for the previous slide. Click here for the next slide.

Prescriber’s Tips

Baron Miller PharmD headshot Baron Miller, PharmD

In my experience, I would rarely prescribe brand-name Zoloft due to its cost. Instead, I would recommend generic sertraline, which offers the same therapeutic benefit and is fairly inexpensive.

Checking with your local pharmacy is always a good first step when trying to save money on your Zoloft prescription. Ask if they have their own discount programs for people without insurance. If you feel that the cost of Zoloft or any other medication might be a barrier between you and better health, talk to your provider to see what they can do for you.

Discuss medication costs and concerns with your prescriber and what your options are, including the following.

  • Getting a 90-day supply
  • Using a mail-order prescription service
  • Using a generic, if available
  • Medication samples
  • Patient assistance programs

Frequently Asked Questions

What Is Zoloft?

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Zoloft, with the active ingredient sertraline, is an antidepressant in the selective serotonin reuptake inhibitor (SSRI) drug class. Zoloft is FDA-approved for the treatment of various conditions, including major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, and premenstrual dysphoric disorder (PMDD).9

How Does Zoloft Work?

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Zoloft primarily works by increasing serotonin levels in the brain, a brain chemical associated with mood regulation.9

Why Is Zoloft So Expensive?

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Brand name medications like Zoloft undergo costly research for safety and effectiveness under the patent. Generics have the same active ingredient and don’t require the same level of testing to sell it, making it a less expensive option.10

Is There a Generic Version of Zoloft?

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Generic versions of Zoloft are available. These generic medications contain the same active ingredient, sertraline, and are considered equal to the brand-name medication.

Can You Use a Zoloft Coupon With Insurance?

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It depends, some savings programs may allow it while others may not. Check with the program you are applying to understand their restrictions on using insurance.

How Can I Lower My Long-Term Prescription Zoloft Costs?

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Getting a 90-day supply, filling your prescription via mail order, and using generics are all ways to lower long-term drug costs. For those who qualify, patient assistance and discount programs can also help you cut costs on your medication.

Can I Use Coupons for Zoloft at My Pharmacy?

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Yes, you can use Zoloft coupons at many pharmacies.

Is There a Zoloft Discount Card Available?

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Yes, there is a Zoloft card available on the manufacturer’s website.

Does the Cost of Zoloft Vary Depending on the Strength?

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It’s possible. Costs may also vary depending on your insurance and the pricing at various pharmacies. The dosage of your prescription may also be a factor.

Sources Update History

ChoosingTherapy.com strives to provide our readers with mental health content that is accurate and actionable. We have high standards for what can be cited within our articles. Acceptable sources include government agencies, universities and colleges, scholarly journals, industry and professional associations, and other high-integrity sources of mental health journalism. Learn more by reviewing our full editorial policy.

  • Medicare and Zoloft. (n.d.). GoodRx.com. Retrieved from https://www.goodrx.com/zolof

  • Medicaid List of Covered Drugs (Formulary). (June, 2024). HealthPartners.com. Retrieved from https://www.healthpartners.com/ucm/groups/public/@hp/@public/documents/

  • TRICARE Formulary Search. (n.d.). Express-Scripts.com. Retrieved from https://www.express-scripts.com/frontend/open-enrollment/tricare/fst/#/

  • Zoloft Savings Card Terms & Conditions. (n.d.). Zoloft.com. Retrieved from https://www.zoloft.com/savings-terms

  • Patient Assistance Programs: Zoloft. (n.d.). RxAssist.org. Retrieved from https://www.rxassist.org/search/search-results-drug-name-build

  • Zoloft. (n.d.). NeedyMeds.org. Retrieved from https://www.needymeds.org/zoloft

  • What Are HSA-eligible Plans? (n.d.). Healthcare.gov. Retrieved from (https://www.healthcare.gov/high-deductible-health-plan/hdhp-hsa-information/

  • Getting a Prescription Filled. (July 8, 2023). MedlinePlus.gov. Retrieved from https://medlineplus.gov/ency/article/001956.htm

  • ZOLOFT- sertraline hydrochloride tablet, film coated. (August 8, 2023). DailyMed.nlm.nih.gov. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm

  • Generic Drugs: Questions & Answers. (March 16, 2021). FDA.gov. Retrieved from https://www.fda.gov/drugs/frequently-asked-questions-popular-topics/generic-drugs-questions-answers

Show more Click here to open the article sources container.

We regularly update the articles on ChoosingTherapy.com to ensure we continue to reflect scientific consensus on the topics we cover, to incorporate new research into our articles, and to better answer our audience’s questions. When our content undergoes a significant revision, we summarize the changes that were made and the date on which they occurred. We also record the authors and medical reviewers who contributed to previous versions of the article. Read more about our editorial policies here.

February 21, 2025
Author: No Change
Reviewer: No Change
Primary Changes: Updated cost information in the “Zoloft Prices” section.
January 22, 2025
Author: No Change
Reviewer: No Change
Primary Changes: Updated cost information in intro paragraph and “Zoloft Prices” section.
October 24, 2024
Author: No Change
Reviewer: No Change
Primary Changes: Updated cost information in intro paragraph and “Zoloft Prices” section.
September 26, 2024
Author: No Change
Reviewer: No Change
Primary Changes: Updated cost information in intro paragraph and “Zoloft Prices” section.
September 9, 2024
Author: No Change
Reviewer: No Change
Primary Changes: Added new sections titled “Zoloft Discount Card”, “RxAssist”, “NeedyMeds”, “HSA Accounts”, “Ask Your Prescriber for Samples”, “Ask About Getting a 90-day Supply”, Fill Your Prescription by Mail-order”, “Zoloft Alternatives”, “Prescriber’s Tips”, “FAQs”; Revised introduction and sections titled “How Much Does Zoloft Cost Without Insurance?”, “How Much Does Zoloft Cost With Insurance?”, “Zoloft Cost Savings Programs”, “How to Get a Zoloft Prescription”; Reviewed and added relevant sources. Edited for readability and clarity.
Show more Click here to open the article update history container.

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Circle Medical – Anxiety and Depression Treatment. Meet with an online doctor today! All prescriptions are based on necessity determined by a medical professional. Diagnosis and prescription over video. Insurance accepted. No membership or hidden fees. Same day appointments. Visit Circle Medical

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