Skip to content
  • Mental Health Issues
    • Anxiety
    • ADHD
    • Bipolar Disorder
    • Depression
    • Grief
    • Narcissism
    • OCD
    • Personality Disorders
    • PTSD
    • Anger
    • Burnout
    • Stress
  • Relationships
    • Dating
    • Marriage
    • Sex & Intimacy
    • Infidelity
    • Relationships 101
    • Best Online Couples Counseling Services
  • Quizzes
    • Anxiety Test
    • ADHD Test
    • Depression Test
    • Burnout Test
    • Stress Quiz
    • All Quizzes
  • Therapy
    • Starting Therapy
    • Types of Therapy
    • Best Online Therapy Providers
    • Online Therapy Reviews & Guides
    • Mindfulness
  • Medication
    • Anxiety Medication
    • Depression Medication
    • ADHD Medication
    • All Psychotropic Medications
    • Best Online Psychiatrist Options
  • Reviews
    • Best Online Therapy
    • Best Online Therapy with Insurance
    • Best Online Therapy for Teens
    • Best Online Therapy for Anxiety
    • Best Online Therapy for Depression
    • Best Online ADHD Treatments
    • Best Online Psychiatry
    • Best Mental Health Apps
    • All Reviews
  • Therapy Worksheets
    • ADHD Worksheets
    • Anxiety Worksheets
    • Depression Worksheets
    • CBT Worksheets
    • DBT Worksheets
    • Therapy Worksheets for Kids
    • Therapy Worksheets for Teens
    • Relationship Worksheets
    • All Therapy Worksheets
  • About Us
    • About Us
    • Editorial Policy
    • Advertising Policy
    • Find a Local Therapist
    • Join Our Free Directory

Join our Newsletter

Get helpful tips and the latest information

Choosing Therapy on Facebook
Choosing Therapy on Instagram
Choosing Therapy on Twitter
Choosing Therapy on Linkedin
Choosing Therapy on Pinterest
Choosing Therapy on Tiktok
Choosing Therapy on Youtube
ChoosingTherapy.com Logo

Newsletter

Search Icon
  • Mental Health Issues
    • Anxiety
    • ADHD
    • Bipolar Disorder
    • Depression
    • Grief
    • Narcissism
    • OCD
    • Personality Disorders
    • PTSD
    • Anger
    • Burnout
    • Stress
  • Relationships
    • Dating
    • Marriage
    • Sex & Intimacy
    • Infidelity
    • Relationships 101
    • Best Online Couples Counseling Services
  • Quizzes
    • Anxiety Test
    • ADHD Test
    • Depression Test
    • Burnout Test
    • Stress Quiz
    • All Quizzes
  • Therapy
    • Starting Therapy
    • Types of Therapy
    • Best Online Therapy Providers
    • Online Therapy Reviews & Guides
    • Mindfulness
  • Medication
    • Anxiety Medication
    • Depression Medication
    • ADHD Medication
    • All Psychotropic Medications
    • Best Online Psychiatrist Options
  • Reviews
    • Best Online Therapy
    • Best Online Therapy with Insurance
    • Best Online Therapy for Teens
    • Best Online Therapy for Anxiety
    • Best Online Therapy for Depression
    • Best Online ADHD Treatments
    • Best Online Psychiatry
    • Best Mental Health Apps
    • All Reviews
  • Therapy Worksheets
    • ADHD Worksheets
    • Anxiety Worksheets
    • Depression Worksheets
    • CBT Worksheets
    • DBT Worksheets
    • Therapy Worksheets for Kids
    • Therapy Worksheets for Teens
    • Relationship Worksheets
    • All Therapy Worksheets
  • About Us
    • About Us
    • Editorial Policy
    • Advertising Policy
    • Find a Local Therapist
    • Join Our Free Directory
  • What Is Focalin?What Is Focalin?
  • Waht Is Concerta?Waht Is Concerta?
  • DifferencesDifferences
  • How They WorkHow They Work
  • Used to TreatUsed to Treat
  • DosagesDosages
  • Side EffectsSide Effects
  • Potential Drug InteractionsPotential Drug Interactions
  • CostCost
  • Focalin Vs. ConcertaFocalin Vs. Concerta
  • How to GetHow to Get
  • Questions to AskQuestions to Ask
  • In My ExperienceIn My Experience
  • Additional ResourcesAdditional Resources

Focalin Vs Concerta: A Comparison

Luke Prest, MD headshot

Author: Luke Prest, MD

Luke Prest, MD headshot

Luke Prest MD

Dr. Luke Prest is an accomplished pediatric pediatrician and expert in child and adolescent development and behavior. His areas of expertise include adolescent ADHD, depression, and anxiety, and preventative mental health care.

See My Bio Editorial Policy
Headshot of Heidi Moawad, MD

Medical Reviewer: Heidi Moawad, MD Licensed medical reviewer

Headshot of Heidi Moawad, MD

Heidi Moawad MD

Heidi Moawad, MD is a neurologist with 20+ years of experience focusing on
mental health disorders, behavioral health issues, neurological disease, migraines, pain, stroke, cognitive impairment, multiple sclerosis, and more.

See My Bio Editorial Policy
Published: March 7, 2024
  • What Is Focalin?What Is Focalin?
  • Waht Is Concerta?Waht Is Concerta?
  • DifferencesDifferences
  • How They WorkHow They Work
  • Used to TreatUsed to Treat
  • DosagesDosages
  • Side EffectsSide Effects
  • Potential Drug InteractionsPotential Drug Interactions
  • CostCost
  • Focalin Vs. ConcertaFocalin Vs. Concerta
  • How to GetHow to Get
  • Questions to AskQuestions to Ask
  • In My ExperienceIn My Experience
  • Additional ResourcesAdditional Resources
Brand name:
Concerta
Generic name:
Methylphenidate Hydrochloride ER
Is the generic available:
Yes
Class of drug:
Stimulant
Boxed warning:
Yes
FDA-approved treatments:
ADHD
Common Off-label Uses (non-FDA approved):
Apathy in Alzheimer’s disease, fatigue in patients with cancer, depression
Common alternatives:

Adderall, Ritalin, Vyvanse

View Drug Class, FDA-Approved Uses, Off-Label Uses, and more

*An off-label use of a medication is a use that is not FDA-approved. Prescribers can decide to use a medication off-label because, in their professional judgment, they believe it may offer a benefit to someone.

Brand name:
Focalin
Generic name:
Dexmethylphenidate Hydrochloride
Is the generic available:
Yes
Class of drug:
Stimulant
Boxed warning:
Yes
FDA-approved treatments:
ADHD
Common Off-label Uses (non-FDA approved):
Treatment-resistant depression, narcolepsy
Common alternatives:

Adderall, Ritalin, Vyvanse

View Drug Class, FDA-Approved Uses, Off-Label Uses, and more

*An off-label use of a medication is a use that is not FDA-approved. Prescribers can decide to use a medication off-label because, in their professional judgment, they believe it may offer a benefit to someone.

Focalin and Concerta are both medications prescribed primarily for attention deficit hyperactivity disorder (ADHD). While these medications are similar in function, the two have some distinct diffences. Concerta contains a mixture of methylphenidate drugs and is only available in extended-release formulations. Focalin contains dexmethylphenidate, the more potent of the methylphenidate salts, and is available in immediate-release and extended-release formulations.

If you’re considering Focalin or Concerta, or want to discuss your current prescription with a provider, you will be limited in your options. Talkiatry is an online psychiatry platform that can and will prescribe stimulant medications, which are controlled substances. This platform can connect you with a provider quickly and offer assessments and prescription consultation.

Boxed Warning: Methylphenidate (Concerta) – Risk of medication misuse or abuse

Click here to open and close the box warning container.

Methylphenidate, the active ingredient in Concerta, has a black box warning. These are the most serious types of warnings from the Food and Drug Administration (FDA). Concerta has a risk of misuse (abuse) which can lead to dependence on the medication.

Concerta is a controlled substance, which means that it’s more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.

Boxed Warning: Dexmethylphenidate (Focalin, Focalin XR) - Risk of misuse and dependence

Click here to open and close the box warning container.

Dexmethylphenidate hydrochloride, the active ingredient in Focalin and Focalin XR, has a black box warning. These are the most serious types of warnings from the Food and Drug Administration (FDA). Dexmethylphenidate hydrochloride has a risk of misuse (abuse) which can lead to dependence on the medication.

Focalin is a controlled substance, which means that it’s more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.

ADVERTISEMENT

ADHD Diagnosis & Treatment at Talkiatry

Talkiatry can match you with a psychiatrist who takes your insurance. Their clinicians can evaluate you for ADHD and prescribe medication. This can include controlled substances if they’re right for you and allowed by your state. Get started with a short online assessment.

Visit Talkiatry

What Is Focalin (Dexmethylphenidate)?

Focalin, with the active ingredient dexmethylphenidate, is a stimulant medication.1,2 Focalin is FDA-approved for the treatment of attention deficit hyperactivity disorder (ADHD).3,4 FDA approval means the drug has undergone testing and meets the safety and efficacy standards of the U.S. Food and Drug Administration.

Focalin can also be prescribed off-label, which means for use not specifically approved by the FDA. A healthcare prescriber may choose a medication off-label if, in their professional opinion, they believe it may still benefit an individual. Off-label uses of Focalin include the treatment of narcolepsy and treatment-resistant depression. 5

What Is Concerta (Methylphenidate)?

Concerta, a stimulant medication, has two types of methylphenidate as active ingredients. This includes dexmethylphenidate, the active ingredient in Focalin.6 Concerta is FDA-approved for the treatment of ADHD.7 Off-label uses of Concerta include the treatment of narcolepsy, treatment-resistant depression, fatigue in patients with cancer, and apathy in Alzheimer’s disease.5,8

What Are the Differences Between Focalin & Concerta?

Focalin and Concerta are both medications prescribed for the treatment of attention deficit hyperactivity disorder (ADHD). The main difference between the two lies in their active ingredients. Concerta contains a mix of methylphenidate drugs: d-methylphenidate and l-methylphenidate.7 Focalin only contains d-methylphenidate, also called dexmethylphenidate.1 As dexmethylphenidate is the more potent of the two, Focalin can be effective at a lower total dose of medication.

Here are the key differences between Focalin versus Concerta:3,4,5,7

Key ComponentsFocalinConcerta
What is the generic name?DexmethylphenidateMethylphenidate
What forms does it come in?Immediate and extended-releaseExtended-release
What are the typical dosages?2.5 - 20 mg tablets for immediate-release
5 - 40 mg capsules for extended-release
18 - 72 mg tablets
Who is approved to take it?Individuals aged 6 and olderIndividuals aged 6 and older

How Do Focalin Vs. Concerta Work?

Focalin and Concerta are stimulant medications that work by increasing levels of norepinephrine and epinephrine in the brain.1,2,6 These chemicals are thought to play a major role in attention, focus, and hyperactivity. By increasing the levels of these chemicals in the brain, individuals with ADHD symptoms can see improvements in their focus while decreasing hyperactivity and impulsivity.

Are Focalin & Concerta the Same?

While Focalin and Conerta share many similarities, these medications are not the same. Both medications are primarily used to treat ADHD, but their active ingredients are different. Also, their formulations are different. Concerta is only available as an extended-release medication. Focalin, however, is available in immediate-release and extended-release formulations.

What Are Focalin & Concerta Used to Treat?

Focalin and Concerta are stimulant medications and, therefore, are FDA-approved for the same use. However, these medications may be used differently when prescribed off-label. This means the medications are being used for the treatment of a condition that is not specifically approved by the FDA.

The table below compares the medical and mental health conditions Focalin & Concerta are used to treat:3,4,5,8

ConditionFocalinConcerta
Attention-deficit hyperactivity disorder (ADHD)FDA-approvedFDA-approved
NarcolepsyOff-labelOff-label
Treatment-resistant depressionOff-labelOff-label
Fatigue in patients with cancerNo*Off-label
Refractory depression in the geriatric populationNo*Off-label
Apathy in Alzheimer diseaseNo*Off-label

*Though the use of Focalin for these conditions is not listed, the medication could likely be used off-label for these conditions, given the similar effect of Concerta on the brain.

Is Focalin or Concerta Better for Anxiety?

The impacts of Focalin and Cocnerta on anxiety can vary among individuals. Both medications are stimulants that may exacerbate anxiety symptoms in some individuals. However, individual responses will differ, and not everyone will experience anxiety symptoms when taking these medications. Neither of these medications is used to treat anxiety.

Which Is Better for ADHD, Focalin or Concerta?

Focalin and Concerta are both effective medications for ADHD. Determining whether Focalin or Concerta is better for ADHD depends on individual responses and specific needs. Individuals may respond better to one medication than the other, and it is difficult to predict these responses. Also, Focalin is available in both immediate-release and extended-release formulations, while Concerta is only available in extended-release formulations. For this reason, one may be preferred over the other depending on the length of impact required.

Different medications can work differently in people. It’s important to discuss what the most appropriate medication is and why with a healthcare professional.

ADVERTISEMENT

ADHD Diagnosis & Treatment at Talkiatry

Talkiatry can match you with a psychiatrist who takes your insurance. Their clinicians can evaluate you for ADHD and prescribe medication. This can include controlled substances if they’re right for you and allowed by your state. Get started with a short online assessment.

Visit Talkiatry

Focalin Vs. Concerta Dosages

Focalin and Concerta are available in a variety of dosages. These dosages vary for each individual based on their individual response. The equivalent dosage for Concerta is often higher than the dosage of Focalin, given the differences in their active ingredients.

Focalin is available in the following forms and strengths:3,4,5

Immediage-release oral tablet

  • 2.5 milligrams (mg)
  • 5 mg
  • 10 mg

Extended-release oral capsule

  • 5 mg
  • 10 mg
  • 15 mg
  • 20 mg
  • 25 mg
  • 30 mg
  • 35 mg
  • 40 mg

Concerta is available in the following forms and strengths:7

Extended-release oral tablet

  • 18 mg
  • 27 mg
  • 36 mg
  • 54 mg

Side Effects of Focalin Vs. Concerta

The side effects of Concerta and Focalin are similar as they share similar active ingredients. The most common side effects of these medications are generally mild and often diminish as the body adjusts to the new medication. Common side effects of stimulant medications such as Focalin and Concerta include decreased appetite, insomnia, and anxiety. While most side effects are mild, some can be serious, requiring immediate medical attention.

Common side effects from taking Focalin or Concerta may include:1,2,5,6

  • Insomnia
  • Headache
  • Exacerbation of tics
  • Anxiety
  • Irritability
  • Decreased appetite
  • Weight loss
  • Abdominal pain
  • Nausea

Serious side effects from taking Focalin or Concerta may include:1,2,5,6

  • Psychotic episodes
  • Seizures
  • Priapism (painful, sustained erections)
  • Heart rhythm abnormalities
  • Allergic reactions
  • Sudden death in those with pre-existing heart problems
  • Hypertension

*All medications, including Concerta and Focalin, have a risk of side effects, including serious side effects. This is not a complete list of side effects. You should talk with your healthcare professional about the benefits and risks of any medication before starting treatment.

Do Focalin or Concerta Cause Brain Fog?

Brain fog or mental fog is a term used to describe a variety of symptoms that typically include slowed thinking, impaired concentration, difficulty multitasking, and memory loss. Brain fog can occur due to a variety of different causes. It is unclear if these medications can cause brain fog, and if individuals will react differently to these medications. It is important to note that ADHD can cause brain fog, and often, the symptoms of brain fog improve with stimulant medications.

Potential Drug Interactions With Focalin & Concerta

Focalin and Concerta have the potential to interact with various medications and supplements, increasing the risk of more severe side effects. It is important to consider these potential interactions when using these medications. Notify your healthcare provider with a complete medication history, including prescription drugs, over-the-counter medications, supplements, and recreational substances.

Taking these medications may make other medications more or less potent, increase the risk of side effects, or decrease their effectiveness. For example, Focalin and Concerta may increase blood pressure, requiring changes in medications to treat hypertension.1,6 These medications can increase blood levels of other drugs, including selective serotonin reuptake inhibitors (SSRIs), anti-seizure medications, and blood thinners.

Disclaimer: Taking certain medications, herbs, or supplements alongside Focalin & Concerta can change how these medications work in your body or increase the risk of serious side effects. This article does not consider all the possible interactions. Please let your doctor, psychiatrists, and pharmacists know about all the products you currently use, such as prescription medication, nonprescription drugs, and herbal supplements. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Focalin Vs. Concerta Cost

The cost of Focalin and Concerta can vary depending on an individual’s insurance coverage and the medication being prescribed. Both of these medications are available in generic formulations, which can significantly decrease their costs. For those experiencing high out-of-pocket costs, various discounts, coupons, and patient assistance programs may be available. Pharmaceutical companies often offer assistance programs to help eligible individuals afford their medications.

ADVERTISEMENT

Online Psychiatry Covered by Insurance

Work with a psychiatrist online. Insurance accepted, and new patients welcome. Get personalized mental care including medication. If allowed in your state and right for you, this can include controlled substances. Start with a short online assessment.

Get Started

Which Is Right for You: Focalin or Concerta?

Choosing between Focalin and Concerta requires careful consideration of individual factors, and the decision should be made in consultation with a healthcare professional. Factors influencing this decision may include an individual’s response to different medications, potential side effects, and pre-existing conditions. It is important to have a thorough discussion with a healthcare provider when considering these medications.

If an in-person consultation is a challenge, online psychiatry services are one option to consider. These platforms offer a convenient and accessible way to discuss medication options with licensed medical professionals.

How to Get a Prescription for Focalin & Concerta

Focalin and Concerta are controlled substances, which means they are only available through a prescription by a licensed healthcare provider. The types of providers who commonly prescribe these medications include psychiatrists, primary care physicians, neurologists, and pediatricians. The first step is to schedule an appointment with your healthcare provider. During the appointment, they can evaluate your specific symptoms and needs to determine if Focalin or Cocnerta is appropriate for addressing your needs.

Questions to Ask Your Health Team About Focalin Vs. Concerta

To prepare for your appointment, make a list of any questions or concerns you may have.

Questions to ask your prescriber about Focalin & Concerta include:

  • Is it safe to take Focalin & Concerta with my other medications?
  • Will Focalin & Concerta be covered by my insurance?
  • Which one has the best results as a treatment for ADHD?
  • Does my medical history increase my risk of side effects for either?
  • How long can I expect side effects to last?
  • How often should I see you for checkups while taking Focalin & Concerta?
  • What should I do if I am unsure whether stimulant medications are right for me?
  • Are there any lifestyle or dietary factors that may impact the effectiveness of these medications?
  • What specific warning signs or symptoms should I look for when taking these medications?
  • What alternative options are available for the treatment of ADHD?

In My Experience

In my experience, Focalin and Concerta are both effective options for the treatment of ADHD. I often use these medications as first-line treatments for my patients with ADHD. I have seen the significant positive impacts these medications have had on their lives.

Luke Prest, MD headshot Luke Prest, MD
Sources

ChoosingTherapy.com strives to provide our readers with mental health content that is accurate and actionable. We have high standards for what can be cited within our articles. Acceptable sources include government agencies, universities and colleges, scholarly journals, industry and professional associations, and other high-integrity sources of mental health journalism. Learn more by reviewing our full editorial policy.

  • Drugs@FDA. (2023). FDA-Approved Drugs. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/

  • Drugs@FDA. (2023). FDA-Approved Drugs. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/

  • DailyMed. (2023). FOCALIN- dexmethylphenidate hydrochloride tablet.  Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm

  • DailyMed. (2023). FOCALIN XR- dexmethylphenidate hydrochloride capsule, extended release. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm

  • Stahl S. M. & Grady M. M. (2017). Stahl’s essential psychopharmacology: prescriber’s guide (Sixth). Cambridge University Press.

  • Drugs@FDA. (2023). : FDA-Approved Drugs. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/

  • DailyMed. (2023). CONCERTA- methylphenidate hydrochloride tablet, extended release.  Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm

  • Verghese, C. (2023). Methylphenidate. StatPearls – NCBI Bookshelf. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK482451/

Show more Click here to open the article sources container.

Your Voice Matters

Can't find what you're looking for?

Request an article! Tell ChoosingTherapy.com’s editorial team what questions you have about mental health, emotional wellness, relationships, and parenting. Our licensed therapists are just waiting to cover new topics you care about!

Request an Article

Leave your feedback for our editors.

Share your feedback on this article with our editors. If there’s something we missed or something we could improve on, we’d love to hear it.

Our writers and editors love compliments, too. :)

Leave Feedback

Additional Resources

To help our readers take the next step in their mental health journey, ChoosingTherapy.com has partnered with leaders in mental health and wellness. ChoosingTherapy.com is compensated for marketing by the companies included below.

ADHD Diagnosis & Treatment at Talkiatry

Talkiatry – can match you with a psychiatrist who takes your insurance. Their clinicians can evaluate you for ADHD and prescribe medication. This can include controlled substances if they’re right for you and allowed by your state. Get started with a short online assessment.

Online Psychiatry

Circle Medical – ADHD Diagnosis and Treatment. Affordable and accessible ADHD evaluations and treatment, including possible controlled substances medication if clinically appropriate. Diagnosis and prescription over video. Insurance accepted. Same & next day appointments available. Visit Circle Medical

ADHD Medication Management + Therapy

Brightside Health – Different people experience ADHD in different ways. That’s why Brightside Health develops personalized plans that are unique to you and offers 1-on-1 support from start to finish. Brightside Health accepts United Healthcare, Anthem, Cigna, and Aetna. No controlled substances. Appointments in as little as 24 hours. Start your free assessment.

ADHD Management Tools

Inflow App – Inflow is the #1 science-based app to help you manage your ADHD. Their support system helps you understand your neurodiverse brain, and build lifelong skills. Free Trial

SPONSORED
Circle Medical - Online ADHD Test

Do you think you have ADHD?

Answer an evidence-based questionnaire for Circles Medical to learn more. Takes 45 seconds.

Take Quiz

Best Online Psychiatry Services

Best Online Psychiatry Services

Online psychiatry, sometimes called telepsychiatry, platforms offer medication management by phone, video, or secure messaging for a variety of mental health conditions. In some cases, online psychiatry may be more affordable than seeing an in-person provider. Mental health treatment has expanded to include many online psychiatry and therapy services. With so many choices, it can feel overwhelming to find the one that is right for you.

Read more

ADHD Newsletter

A free newsletter for those impacted by ADHD. Get helpful tips and the latest information.

ChoosingTherapy.com Logo White
  • About Us
  • Contact Us
  • Write for Us
  • Careers
  • Editorial Policy
  • Advertising Policy
  • Privacy Policy
  • Terms of Service

FOR IMMEDIATE HELP CALL:

Medical Emergency: 911

Suicide Hotline: 988

View More Crisis Hotlines
Choosing Therapy on Facebook
Choosing Therapy on Instagram
Choosing Therapy on X
Choosing Therapy on Linkedin
Choosing Therapy on Pinterest
Choosing Therapy on Tiktok
Choosing Therapy on Youtube

© 2025 Choosing Therapy, Inc. All rights reserved.

X