*An off-label use of a medication is a use that is not FDA-approved. Prescribers can decide to use a medication off-label because, in their professional judgment, they believe it may offer a benefit to someone.
*An off-label use of a medication is a use that is not FDA-approved. Prescribers can decide to use a medication off-label because, in their professional judgment, they believe it may offer a benefit to someone.
Focalin (dexmethylphenidate) and Ritalin (methylphenidate) are medications most commonly used to treat attention deficit hyperactivity disorder (ADHD). While these medications are similar, their active ingredients are different. Ritalin is a mixture of two methylphenidate drugs. Focalin only contains one of these active ingredients, which is the more potent of the two. Focalin and Ritalin have similar side effects, but individuals may respond differently.
If you’re considering Focalin or Adderall, or want to discuss your current prescription with a provider, you will be limited in your options. Circle Medical is an online psychiatry platform that can and will prescribe stimulant medications, which are controlled substances. This platform can connect you with a provider quickly and offer assessments and prescription consultation.
Boxed Warning: Dexmethylphenidate (Focalin, Focalin XR) - Risk of misuse and dependence
Dexmethylphenidate hydrochloride, the active ingredient in Focalin and Focalin XR, has a black box warning. These are the most serious types of warnings from the Food and Drug Administration (FDA). Dexmethylphenidate hydrochloride has a risk of misuse (abuse) which can lead to dependence on the medication.
Focalin is a controlled substance, which means that it’s more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.
Boxed Warning: Methylphenidate (Ritalin, Ritalin LA) – Risk of medication misuse or abuse
Methylphenidate, the active ingredient in Ritalin and Ritalin LA, has a black box warning. These are the most serious types of warnings from the Food and Drug Administration (FDA). Methylphenidate has a risk of misuse (abuse) which can lead to dependence on the medication.
Ritalin is a controlled substance, which means that it’s more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.
Are Ritalin & Focalin the Same Thing?
While Focalin and Ritalin are stimulant medications used in the treatment of ADHD, they are not the same thing. Ritalin contains two types of methylphenidate drugs; the most potent is called dexmethylphenidate. Focalin only contains dexmethylphenidate and is, therefore, more potent than Ritalin.1, 2 These medications have similarities in potential side effects and effectiveness. Still, the choice between them depends on individual responses and specific treatment needs.
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What Are the Differences Between Focalin & Ritalin?
Focalin and Ritalin are both medications used to manage attention deficit hyperactivity disorder (ADHD). The main difference between these medications is their active ingredient. Ritalin contains two types of methylphenidate, while Focalin only contains the most potent of these types of methylphenidate. This means that Focalin may be more effective at lower doses.
Here are the key differences between Focalin versus Ritalin:1, 2, 3, 4
Key Components | Focalin | Ritalin |
What is the generic name? | Dexmethylphenidate | Methylphenidate (racemic) |
What forms does it come in? | Immediate-release and Extended-release tablets | Short-acting and Long-acting tablets |
What are the typical dosages? | 2.5 - 40 mg, depending on the type of release tablet | 5-60 mg, depending on short vs long-acting |
Who is approved to take it? | Adults and children six years and older | Adults and children six years and older |
How Do Focalin & Ritalin Work?
Focalin and Ritalin work by influencing chemicals in the brain that play an important role in attention and impulsivity. These medications are stimulant medications that increase norepinephrine and dopamine in the brain.1, 2 By increasing these chemicals in the brain, Focalin and Ritalin can create more balance in the brain. This can lead to enhanced focus and concentration while reducing hyperactivity and impulsivity.
What Are Focalin & Ritalin Used to Treat?
Focalin and Ritalin are medications most often used to treat attention deficit hyperactivity disorder (ADHD). However, there are other FDA-approved uses for these medications. Both of these medications are also used off-label. This means they are being used to treat a condition not approved by the FDA.
The table below compares the medical and mental health conditions Focalin and Ritalin are used to treat:1, 2, 5, 6, 7
Condition | Focalin | Ritalin |
ADHD | FDA-Approved | FDA-Approved |
Narcolepsy | Off-label | FDA-Approved |
Treatment-resistant depression | Off-label | Off-label |
Fatigue in cancer patients | No | Off-label |
Apathy in Alzheimer’s disease | No | Off-label |
Focalin Vs. Ritalin Efficacy in Managing ADHD
Focalin and Ritalin are both considered highly effective in managing ADHD symptoms. Focalin contains the more potent form of methylphenidate and is, therefore, a more potent medication. This means it may be more effective at a lower dose. However, individual responses to these medications will vary, and some may see more benefit of one drug over the other. It is important for an individual to work closely with a healthcare provider to determine which medication is best for them.
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Side Effects of Focalin & Ritalin
Because Focalin and Ritalin contain similar ingredients, their side effects are similar. The most common side effects of these medications are typically mild and will often resolve as the body adjusts to the new medication. These side effects may include insomnia, decreased appetite, and nervousness. Some side effects, however, can be severe and require immediate medical attention.
Common side effects from taking Focalin or Ritalin may include:1, 2, 5, 7, 8
- Insomnia
- Decreased Appetite
- Weight loss
- Dry mouth
- Abdominal pain
- Headache
- Nervousness
- Irritability
- Restlessness
*All medications, including Focalin and Ritalin, have a risk of side effects, including serious side effects. This is not a complete list of side effects. You should talk with your healthcare professional about the benefits and risks of any medication before starting treatment.
Severe side effects from taking Focalin or Ritalin may include:*
- Seizures
- Chest pain
- Heart palpitations
- Shortness of breath
- Priapism (sustained painful erections)
- Sudden death in those with preexisting heart problems
- Psychotic episodes
- Swelling of the face, throat, or tongue
*All medications, including Focalin and Ritalin, have a risk of side effects, including serious side effects. This is not a complete list of side effects. You should talk with your healthcare professional about the benefits and risks of any medication before starting treatment.
Warnings & Precautions for Focalin & Ritalin
The risks to consider when taking Focalin and Ritalin are similar as they belong to the same drug class. When taking these medications, the risks require careful consideration and discussion with a healthcare provider.
Risks to consider when taking Focalin and Ritalin include:1, 2, 3, 4
- Allergic reactions: Both medications can trigger allergic reactions, which may manifest as hives, itching, swelling of the mouth/face, dizziness, or difficulty breathing. Immediate medical attention is crucial if these symptoms occur.
- Pregnancy: There may be risks to the fetus when taking stimulants during pregnancy. However, the risks are not well-established. It is important to consult with your healthcare provider if you are pregnant and on these medications.
- Breastfeeding: A small amount of these medications is excreted in the breastmilk, but it is unclear if this affects breastfed infants. Consult with your healthcare provider if you are breastfeeding and taking these medications.
- Those with serious cardiac conditions: Both medications may cause severe cardiovascular reactions, including sudden death, in those with serious heart problems.
- Those with preexisting psychotic disorders: Stimulant medications may exacerbate symptoms of psychotic behavior in individuals with a history of psychotic episodes.
- Those with a history of drug abuse: CNS stimulant medications have a high potential for abuse and dependence. Those with a history of substance abuse should be cautious when using Focalin or Ritalin.
Potential Drug Interactions With Focalin & Ritalin
Focalin and Ritalin can interact with other medications and supplements, potentially leading to more severe side effects. These potential interactions should be considered when using these medications. It is important to tell your healthcare provider your full medication history, including prescription medications, over-the-counter drugs, supplements, and recreational substances.
Ritalin and Focalin can affect blood pressure and should be used carefully with drugs used to manage hypertension. These medications may also inhibit the breakdown of some drugs in the body, leading to prolonged effects and risk of overdose. These drugs include selective serotonin reuptake inhibitors (SSRIs), anti-seizure medications, and coumarin blood thinners.5
Disclaimer: Taking certain medications, herbs, or supplements alongside Focalin and Ritalin can change how these medications work in your body or increase the risk of serious side effects. This article does not consider all the possible interactions. Please let your doctor, psychiatrists, and pharmacists know about all the products you currently use, such as prescription medication, nonprescription drugs, and herbal supplements. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
Focalin Vs. Ritalin Dosages for FDA-Approved Treatment
The dosages for Focalin and Ritalin will vary from person to person and are based on factors such as age, weight, individual response, and drug formulation. Both Focalin and Ritalin come in short-acting and long-acting formulations. It is important to take these medications as prescribed by your healthcare provider to have the maximum effectiveness and reduce the risk of side effects.
Focalin is available in the following forms and strengths in milligrams (mg):2, 4
- Immediate-release oral tablet: 2.5 mg, 5 mg, 10 mg
- Extended-release oral capsule: 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, 30 mg, 35 mg, 40 mg
Ritalin is available in the following forms and strengths in milligrams (mg):1, 3
- Oral tablet: 5 mg, 10 mg, 20 mg
- Extended-release oral capsule: 10 mg, 20 mg, 30 mg, 40 mg
Which Is Stronger, Focalin or Ritalin?
The strength of Focalin and Ritalin is dependent on the dose of medication. However, Focalin is more potent than Ritalin due to the form of methylphenidate it contains (dexmethylphenidate). This means that Focalin can be effective at lower doses. However, the choice between the two medications depends on individual responses and specific treatment needs.
Focalin Vs Ritalin Cost
The cost of Focalin and Ritalin can vary significantly depending on the type of insurance, pharmacy, the formulation of the drug, and whether you are buying the generic or brand-name versions. The generic version of these medications is often cheaper than the brand-name version. Some insurances will cover the cost of these prescription drugs, while others may not. If insurance does not cover these medications, there are often ways to lower the cost, including manufacturer discounts, coupons, and patient assistance programs.
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Which Is Right for You: Focalin or Ritalin?
The choice between Focalin and Ritalin for managing ADHD is a decision that should be made with careful consideration by you and your healthcare provider. Factors that influence this decision include your specific symptoms, medical history, tolerance to stimulants, and potential side effects. It is important to consult with a healthcare professional to assess your situation and receive personalized recommendations.
How to Get a Prescription for Focalin & Ritalin
Focalin and Ritalin are controlled substances and are only available through a prescription. The type of healthcare providers that most often prescribe Focalin and Ritalin include psychiatrists, primary care physicians, neurologists, and pediatricians. If you are considering taking Focalin or Ritalin, the first step would be to schedule an appointment with a healthcare provider. These providers can assess your situation and determine if Focalin or Ritalin could benefit you.
Questions to Ask Your Health Team About Focalin & Ritalin
Honest and effective communication with your prescriber is necessary when considering Focalin or Ritalin as part of a treatment plan. To make the most of your appointment, be prepared with any questions or concerns you may have.
Questions to ask your prescriber about Focalin and Ritalin include:
- Is it safe to take Focalin or Ritalin with my other medications?
- Will Focalin or Ritalin be covered by my insurance?
- Which one has the best results as a treatment for ADHD?
- Does my medical history increase my risk of side effects for either?
- How long can I expect side effects to last?
- How often should I see you for checkups while taking Focalin or Ritalin?
- What should I do if I am unsure whether ADHD medications are right for me?
- Are there any lifestyle or dietary restrictions I should be aware of when taking these medications?
- How should I manage a missed dose?
- Will my insurance cover the cost of these medications?
- What are the potential long-term effects of these medications?
- How can I compare ADHD medications, such as Focalin vs Concerta?
In My Experience
Additional Resources
To help our readers take the next step in their mental health journey, Choosing Therapy has partnered with leaders in mental health and wellness. Choosing Therapy is compensated for marketing by the companies included below.
Online Psychiatry
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ADHD Management Tools
Inflow App – Inflow is the #1 science-based app to help you manage your ADHD. Their support system helps you understand your neurodiverse brain, and build lifelong skills. Free Trial
For Further Reading
- Treatment for Adult ADHD: Medication, Therapy, & Self-Help Strategies
- Non Stimulant ADHD Medication: 6 Options
- Focalin (Dexmethylphenidate): Uses, Dosage, Side Effects, & Warnings
- Ritalin: Uses, Dosage, Side Effects, & Warnings
- Attention-Deficit/Hyperactivity Disorder (ADHD) – CDC
- Focalin Vs Adderall: Differences & Which to Take
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Online psychiatry, sometimes called telepsychiatry, platforms offer medication management by phone, video, or secure messaging for a variety of mental health conditions. In some cases, online psychiatry may be more affordable than seeing an in-person provider. Mental health treatment has expanded to include many online psychiatry and therapy services. With so many choices, it can feel overwhelming to find the one that is right for you.