After our team used the top online medication-assisted treatment (MAT) programs, I compiled this list of the best options out there today. Some services focus on specific conditions like alcohol or opioid use disorder, while others cover a wider range of addictions. The best programs combine affordability, insurance acceptance, and effective medication support to provide a clear pathway to recovery.
Our top three choices should work well for anyone seeking medication-assisted treatment for substance use:
- Workit Health: Takes a “whole person” approach, with MAT for a variety of substance use disorders, plus treatment for co-occurring disorders. Accepts many major health insurance providers but is only available in 10 states so far.
- Eleanor Health: Includes psychiatry and therapy along with MAT for multiple substances. Takes major insurance plans and offers cash-pay at a flat $249 monthly. Currently in 15 states.
- PursueCare: Works with multiple substance use issues, including opioids, alcohol, stimulants, and tobacco. Only available in six Eastern states, but takes major health insurance plans. In-house pharmacy with optional home delivery.
Editors Note:
We regularly review and update our content to provide the most accurate and current information. After a full round of research for each MAT program, we’ve added Affect Therapeutics as Best for Contingency Management. We’ve also added a few alternatives in our “Other Options to Consider” list for more specialty offerings.
Cost: $129–$300 monthly
Insurance Accepted: Yes
Services: MAT for OUD & AUD; Treatment for co-occurring disorders; Therapy; Peer support
States Served: AZ, FL, IL, MI, MT, NJ, NM, OH, TX, WA
Workit Health was founded by two women in recovery themselves, offering MAT, coaching, and treatment for co-occurring disorders like anxiety, depression, HIV, or Hepatitis C, along with hundreds of self-paced education modules.
Cost: $249 monthly
Insurance Accepted: Yes
Services: MAT for OUD/AUD/Stimulant use; Therapy; Psychiatry; Peer support
States Served: CO, FL, ID, IL, LA, MA, MO, MT, NJ, NM, NC, OH, PA, TX, WA
Eleanor Health offers a whole-person approach to addiction care, including multiple medication options for opioids, alcohol, and stimulants, psychiatry and therapy for other mental health concerns, and peer support. It offers in-person care in addition to its online services in some states. It’s in-network with most major insurance plans, or users can pay out-of-pocket for $249 monthly.
Cost: $50 per session
Insurance Accepted: Yes
Services: MAT for OUD/AUD/Stimulants/Tobacco; Therapy; Pharmacy
States Served: CT, KY, ME, NH, OH, WV
One of the standout features of PursueCare is its in-house pharmacy, which can ship medications directly to your door instead of to a local pharmacy, saving you time and hassle. It offers MAT for opioids, alcohol, and tobacco, and provides dual-diagnosis care for other mental health concerns through psychiatry and therapy. The cost of care is a flat $50 per session and/or $85 monthly for psychiatry services, though many major health plans are accepted, which could greatly lower that cost.
Cost: $245 monthly
Insurance Accepted: Yes
Services: MAT for OUD
States Served: AZ, CA, CT, FL, ME, MD, MT, NJ, NY, PA, TX, VT, VA, WA
Ophelia Health offers treatment for opioid use disorder through Suboxone, while also helping treat co-occurring conditions like depression, anxiety, and insomnia. One of its more unique features is its 24/7 virtual emergency support with access to triage nurses. Services are offered for $245 monthly, though it’s in-network with many major insurance plans.
Cost: $175–$449 monthly
Insurance Accepted: Yes
Services: MAT for AUD; Therapy; Coaching
States Served: Nationwide
Ria Health provides comprehensive care for those wanting to change their relationship with alcohol, offering naltrexone, recovery coaching from licensed providers, and treatment for co-occurring conditions. It’s designed for those who want to quit drinking altogether, as well as for people wanting to cut back, and the plan includes a Bluetooth breathalyzer for tracking progress.
Cost: Varies based on insurance
Insurance Accepted: Yes
Services: MAT for various substances; Counseling; Psychiatry; Contingency Management
States Served: AZ, CA, CO, FL, IL, IN, IA, NE, NV, NM, NC, OH, OR, TX, VA, WA
Affect Therapeutics offers MAT services for alcohol, cannabis, stimulants, and opioids in several states across the country. However, what stands out is its contingency management program: Members can earn small amounts of real money for completing addiction recovery challenges.
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Other Options to Consider
- For naltrexone: Sunnyside is an app to help people reduce or quit drinking. Users can also access naltrexone subscriptions through the app. Another option, Oar Health, offers quick access to naltrexone without requiring any type of telehealth appointment.
- For suboxone: Bicycle Health offers Suboxone for opioid use disorder in select states, often providing same-day prescriptions you can pick up at a local pharmacy. QuickMD offers a similar solution in 40 states and counting, typically with multiple same-day sessions available.
- For teens: Charlie Health offers a virtual intensive outpatient program designed to help teens through a range of mental health concerns, including addiction.
Detailed Company Reviews
- Cost: $129–$300 monthly
- Insurance Accepted: Yes
- Services: MAT for OUD & AUD; Treatment for co-occurring disorders; Therapy; Peer support
- States Served: AZ, FL, IL, MI, MT, NJ, NM, OH, TX, WA
Workit Health is an online addiction recovery program offering comprehensive care, including medication-assisted treatment, dual-diagnosis support, and recovery coaching. Its holistic approach to addiction recovery is why I gave it the award for best overall online MAT program.
Pros & Cons
- Offers several types of medication-assisted treatment for different addictions
- Can also prescribe PrEP for HIV prevention
- Offers hundreds of educational courses on recovery-related topics
- Patients can access care through their online platform or mobile app
- Online community events
- Difficult to initially determine the cost of care
- Medicaid plans are not accepted in some states
Cost
The cost of treatment with Workit Health varies based on the specific program and whether you’re paying out of pocket or using insurance. Below is an overview of current self-pay pricing:
Opioid Use Disorder Program (Self-Pay):
- Sign-up fee: $15
- Initial appointment: $90
- Ongoing subscription: $75 per week (billed monthly at $300)
Alcohol Use Disorder Program (Self-Pay):
- First month: $99
- Ongoing subscription: $129 monthly
If you’re using insurance, your copay and out-of-pocket expenses may be significantly lower depending on your specific plan.
Overview
Workit Health is an online MAT program that provides a wide range of services, including medication-assisted treatment, dual-diagnosis services, and recovery coaching. Workit Health treats several forms of addiction, including opioid use disorder and alcohol use disorder. It now also offers medication for weight management.
Workit Health’s care teams include psychiatrists, therapists, and recovery counselors, offering comprehensive personalized support. Patients can choose one-on-one sessions with licensed mental health professionals or participate in group therapy. Additionally, Workit Health provides nationwide recovery coaching for other behaviors, including issues with compulsive gambling, sex, pornography, and disordered eating.
As for medication, Workit Health offers treatment for alcohol and opioid disorders. Most medications prescribed by Workit Health are covered by insurance, but final pricing is determined by the pharmacy, not Workit Health. Common prescriptions from Workit Health providers include naltrexone, Suboxone, and Campral.
A standout feature of Workit Health is its extensive library of online educational courses, covering topics like addiction, coping strategies, and recovery tools. This comprehensive and inclusive approach impressed our team, earning Workit Health the Best Overall MAT program title.
To learn more about this program, check out our in-depth review of Workit Health.
- Cost: $249 monthly
- Insurance Accepted: Yes
- Services: MAT for OUD/AUD/Stimulant use; Therapy; Psychiatry; Peer support
- States Served: CO, FL, ID, IL, LA, MA, MO, MT, NJ, NM, NC, OH, PA, TX, WA
Eleanor Health is an online addiction treatment program that also offers therapy to treat both substance abuse disorders and co-occurring mental health concerns. Winning the award for Best MAT for Dual-Diagnosis, Eleanor Health curates personalized treatment plans for patients with multiple diagnoses or presenting issues.
Pros & Cons
- Offers several medications to assist with treating multiple substance use disorders
- Online and in-person treatment available in select states
- Includes psychiatry and therapy for co-occurring mental health issues
- Out-of-pocket costs depend on your location and provider availability
- No monthly or annual flat rates or subscription options
Cost
The cost of care at Eleanor Health depends on your personalized treatment plan and insurance coverage. The company accepts most major insurance providers and offers discounted rates for those paying out of pocket. For those without insurance, Eleanor Health’s self-pay program is available at $249 per month.
Overview
Specializing in medication-assisted treatment (MAT) and therapy, Eleanor Health supports people with substance use disorders and co-occurring mental health conditions.
Understanding that addiction is often accompanied by mental health issues such as depression, anxiety, and PTSD, Eleanor Health offers a holistic approach to recovery. By combining medication and therapy from the outset, their program targets both addiction and mental health, aiming to support lasting sobriety.
Medication costs will depend on the specific prescription, dosage, and quantity needed. Many insurance plans cover these medications or require only a small copay. For those paying out of pocket, medication costs are separate from Eleanor Health’s monthly program fee. Common prescriptions from Eleanor Health providers include:
- Buprenorphine
- Naltrexone
- Vivitrol
- Suboxone
- Campral
- Chantix
Patients have access to various therapeutic options, including individual and group therapy, as well as family and couples counseling. This wide range of services ensures that your needs and the dynamics of your relationships are addressed during the recovery process.
To learn more about this program, check out our in-depth review of Eleanor Health.
- Cost: $50 per session
- Insurance Accepted: Yes
- Services: MAT for OUD/AUD/Stimulants/Tobacco; Therapy; Pharmacy
- States Served: CT, KY, ME, NH, OH, WV
PursueCare stands out as a comprehensive program for MAT treatment and mental health care, seamlessly integrating addiction and mental health support. A key highlight is its in-house pharmacy, PursueCareRx, which can send prescriptions directly to your door. They offer treatment for many addictions and diagnoses, winning our award for the Best MAT for Multiple Addictions.
Pros & Cons
- Offers medication-assisted treatment (MAT) for multiple types of addiction, including opioids, alcohol, and tobacco
- Provides dual-diagnosis care for co-occurring mental health conditions
- Features an in-house pharmacy
- Offers financial aid
- Services are only available in six US states
Cost
Out-of-pocket costs for MAT services through PursueCare are $50 per session. The psychiatry plan is available for $85 per month, which includes a monthly visit with a psychiatrist and continued support from a dedicated case manager.
PursueCare accepts most major insurance plans, which can significantly lower your costs. Even without insurance, it remains one of the more affordable options for virtual mental health and addiction care.
Overview
Starting with PursueCare is straightforward and designed to feel supportive and shame-free from the beginning. The platform offers virtual care for substance use disorders, including medication-assisted treatment (MAT), therapy, and psychiatry for co-occurring mental health conditions. Services are available in select states and most major insurance plans are accepted. If you’re uninsured, self-pay options begin at $50 per session.
PursueCare prescribes medications such as Suboxone for opioid use, Naltrexone for alcohol dependence, and Chantix for tobacco cessation. These FDA-approved options can reduce cravings and withdrawal symptoms and help lower the risk of relapse.
Unlike many MAT-only programs, PursueCare also offers full psychiatry services. Their $85/month psychiatry plan includes medication management for a wide range of mental health concerns, whether or not addiction is involved. Therapy is also available, and clients can participate in individual or group counseling with licensed professionals. These services can be added as part of a recovery plan or accessed on their own by anyone seeking support.
To learn more about this program, check out our in-depth review of PursueCare.
- Cost: $245 monthly
- Insurance Accepted: Yes
- Services: MAT for OUD
- States Served: AZ, CA, CT, FL, ME, MD, MT, NJ, NY, PA, TX, VT, VA, WA
Ophelia is a medication-assisted treatment for those struggling with opioid use disorder and common co-occurring conditions such as depression, anxiety, and insomnia. I chose Ophelia as the Best MAT for Opioid Use Disorder because of its comprehensive care model for online opioid addiction treatment.
Pros & Cons
- Accepts a wide range of major insurance plans
- Offers support for co-occurring conditions such as anxiety, depression, and insomnia
- 24/7 virtual access to triage nurses for urgent care needs
- Does not include therapy or counseling services
- Only treats opioid use disorder; other addictions are not covered
Cost
Ophelia costs $245 monthly. This plan does not include the cost of medication. Insurance is accepted, so costs may be lower for those with in-network coverage. Ophelia does charge a $20 no-show fee for missed appointments.
Overview
Ophelia offers online medication-assisted treatment (MAT) specifically for individuals with opioid use disorder. The service is available in select states and accepts many major insurance plans. Without insurance, the program costs $245 per month, not including the cost of medication. After a medical evaluation, a licensed clinician may prescribe Suboxone, which can often be picked up at a local pharmacy the same day as your initial virtual appointment.
A key feature of Ophelia’s care model is its team of dedicated care coordinators. These professionals guide patients through every step of treatment, helping with scheduling, insurance questions, and pharmacy coordination. Many care coordinators have backgrounds in social work, psychology, or public health. For those interested in extra support, they can also help connect patients with individual or group peer support during recovery.
To learn more about this program, check out our in-depth review of Ophelia.
- Cost: $175 – $449 monthly
- Insurance Accepted: Yes
- Services: MAT for AUD; Therapy; Coaching
- States Served: Nationwide
Ria Health is an MAT provider designed to support individuals with alcohol use disorder, whether their goal is to reduce drinking or achieve complete sobriety. Recognized as the top program for alcohol use disorder and mindful drinking, Ria stands out for its personalized approach, offering customized treatment plans that align with each person’s unique goals and needs.
Pros & Cons
- Provides medication-assisted treatment for alcohol use disorder and moderate drinking
- Treats co-occurring mental health conditions
- Available in all 50 states
- Offers recovery coaching from licensed mental health professionals
- Not available to patients under the age of 18
- Does not currently accept Medicaid or Medicare Advantage Plans
Cost
Ria Health’s pricing depends on your selected plan and whether you’re using insurance, with typical out-of-pocket costs ranging from $175 to $449 per month. The program accepts most major insurance providers, which can help lower costs significantly. For those without coverage, upfront fees may be higher before transitioning to monthly billing.
Visit our full Ria Health review for more details on pricing.
Overview
Ria Health offers a fully virtual medication-assisted treatment (MAT) program for individuals with alcohol use disorder (AUD). Available in all 50 states, the program includes personalized care plans, medication management, and recovery coaching—all accessible via app or personal device. Monthly costs range from $175 to $449, though many major insurance plans are accepted, potentially reducing out-of-pocket expenses.
Ria’s approach centers on FDA-approved medications designed to reduce cravings and ease withdrawal symptoms, including options like naltrexone, acamprosate, and gabapentin. Patients can also be treated for co-occurring conditions such as anxiety or depression. A notable option offered is The Sinclair Method (TSM), a science-backed strategy that blocks the brain’s reward system while drinking. If MAT is prescribed, medication is sent to the patient’s local pharmacy, and each member receives a Bluetooth breathalyzer to monitor their progress—both included in the program.
The program also features weekly one-on-one sessions with licensed recovery coaches who use evidence-based methods like CBT and Motivational Interviewing. Group support sessions are available as well, offering peer accountability and community. Progress is closely monitored using BAC readings, mental health assessments, and lab results. Ria recommends a minimum 12-month commitment to see lasting results, though some individuals may complete the program sooner based on their progress and goals.
To learn more about this program, check out our in-depth review of Ria Health.
- Cost: Varies based on insurance
- Insurance Accepted: Yes
- Services: MAT for multiple substances; Therapy; Psychiatry; Contingency Management
- States Served: AZ, CA, CO, FL, IL, IN, IA, NE, NV, NM, NC, OH, OR, TX, VA, WA
Affect Therapeutics offers every level of care for addiction treatment, all within a convenient app. Its contingency management program means you can earn small sums of money for completing various challenges.
Pros & Cons
- Earn real money for completing challenges
- MAT for various substances available
- Whole-person services, including MAT, counseling/psychiatry, and in-app education and challenges
- Only in 16 states so far
- Can only access addiction treatment through insurance and costs are unclear
Cost
Affect Therapeutics’ addiction treatment program costs are unclear. The program cannot be accessed without insurance, and each member will have different coverage and copays based on their insurance plans.
Overview
Affect Therapeutics offers addiction treatment, including MAT, for multiple substance use addictions in 16 states, and it’s beginning to offer mental health treatment as well in a few states.
Its addiction treatment program offers MAT, counseling, psychiatry for co-occurring mental health conditions, and challenges in the app that let you earn small sums of real money upon completion. It claims that many members can access the program for free through their insurance, though copays will vary based on your plan.
The contingency management program allows members to earn money after completing challenges. This will be small sums, such as $0.05 for reading an article or a couple dollars for attending a group meeting. While it doesn’t sound like much, seeing the number go up in your app tracker can be quite motivating, and is a science-backed approach for maintaining addiction treatment.
Learn more in our Affect Therapeutics review.
Comparing Our Top Picks
Here’s a quick comparison of pricing, features, and availability for our top five picks.
| Cost | $129–$300 monthly | $249 monthly | $50 per session | $245 monthly | $175–$449 monthly | Varies based on insurance |
| Accepts Insurance | ||||||
| Offers Dual-Diagnosis Services | ||||||
| Nationwide Coverage | ||||||
| Services Offered | MAT for OUD/AUD/Stimulant Abuse; Therapy; Peer support | MAT for OUD/AUD/Stimulant Abuse; Therapy; Peer support | MAT for OUD/AUD/Stimulants/Tobacco; Therapy; Pharmacy | MAT for OUD | MAT for AUD; Therapy; Coaching | MAT for various substances; Counseling; Psychiatry; Contingency Management |
| Cost | |||||
| $129–$300 monthly | $249 monthly | $50 per session | $245 monthly | $175–$449 monthly | Varies based on insurance |
| Accepts Insurance | |||||
| Offers Dual-Diagnosis Services | |||||
| Nationwide Coverage | |||||
| Services Offered | |||||
| MAT for OUD/AUD/Stimulant Abuse; Therapy; Peer support | MAT for OUD/AUD/Stimulant Abuse; Therapy; Peer support | MAT for OUD/AUD/Stimulants/Tobacco; Therapy; Pharmacy | MAT for OUD | MAT for AUD; Therapy; Coaching | MAT for various substances; Counseling; Psychiatry; Contingency Management |
Frequently Asked Questions
What is medication-assisted treatment?
Medication-assisted treatment involves utilizing both medication and counseling for those recovering from addiction. Research shows that medication-assisted treatment can increase patients’ chances of remaining sober and reduce the risk of relapse and overdose.1
Is there such a thing as at-home rehab?
Yes, online rehab can be a great option for those wanting to recover from home. If you’ve tried in-person medication-assisted treatment or addiction therapy in the past and found it difficult to commit to a program due to busy schedules, lack of transportation, or because you live in a remote area without accessible care, an online medication-assisted treatment program could be a good fit for you.
What is the most successful treatment for addiction?
Addiction treatment is most successful when it combines behavioral therapy with medication. This is considered a “whole person” approach, helping someone break their addiction with medication while also changing behaviors and addressing any underlying reason for the addiction to have begun in the first place, such as mental health concerns like depression.
What medication is used to remove addiction?
Medications such as naltrexone, Suboxone, and methodone are commonly used to treat addiction. They work by blocking the euphoric feelings of alcohol and opioids in the pleasure centers of the brain.
What is the "three-day rule" for Suboxone?
The “Three-Day Rule” is a federal regulation that permits healthcare providers, who are not specifically registered to treat opioid use disorder (OUD), to administer (but not prescribe) narcotic medications like Suboxone to patients experiencing acute withdrawal symptoms. This provision allows for administering a single day’s medication at a time, for up to 72 hours, while arrangements are made for the patient’s referral to appropriate treatment. Importantly, these 72 hours cannot be extended or renewed.11
What is the new name for medication assisted treatment?
Medication assisted treatment is a broad term that refers to a variety of medications for treating different substance use disorders. However, organizations like the National Institute on Drug Abuse (NIDA) have adopted the term medication for opioid use disorder (MOUD) as a more specific term for that form of treatment.
ChoosingTherapy.com strives to provide our readers with mental health content that is accurate and actionable. We have high standards for what can be cited within our articles. Acceptable sources include government agencies, universities and colleges, scholarly journals, industry and professional associations, and other high-integrity sources of mental health journalism. Learn more by reviewing our full editorial policy.
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Substance Abuse and Mental Health Services Administration. (n.d.). Medications for Substance Use Disorder. Retrieved from: https://www.samhsa.gov/medications-substance-use-disorders
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American Psychological Association. (2019, June 19). “Whole-Person Approach Needed to Solve Opioid Epidemic,” Says APA. Retrieved from: https://www.apa.org/news/press/releases/2019/06/whole-person-opioid-epidemic
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Greenstein, Luna. (2017, October 4). Understanding a Dual Diagnosis. National Alliance on Mental Health. Retrieved from: https://www.nami.org/Blogs/NAMI-Blog/October-2017/Understanding-Dual-Diagnosis
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National Institute on Drug Abuse. (2021, December). Medications to treat opioid use disorder research report. Retrieved from: https://nida.nih.gov/download/21349/medications-to-treat-opioid-use-disorder-research-report.pdf?v=99088f7584dac93ddcfa98648065bfbe
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Church, C. (2025, April 14). Workit health review: cost, pros & cons, & who it’s right for. ChoosingTherapy.com. Retrieved from https://www.choosingtherapy.com/workit-health-review/
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Church, C. (2025, May 14). Eleanor health review: cost, pros & cons, & who it’s right for. ChoosingTherapy.com. Retrieved from https://www.choosingtherapy.com/eleanor-health-review/
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Church, C. (2025, May 23). Pursuecare review: cost, pros & cons, & who it’s right for. ChoosingTherapy.com. Retrieved from https://www.choosingtherapy.com/pursuecare-review/
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Church, C. (2025, May 14). Ophelia review: cost, pros & cons, & who it’s right for. Choosing Therapy.com. Retrieved from https://www.choosingtherapy.com/ophelia-health-review/
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Church, C. (2025, April 11). Ria health review: cost, pros & cons, & who it’s right for. ChoosingTherapy.com. Retrieved from https://www.choosingtherapy.com/ria-health-review/
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Guarnotta, E. (2025, April 23). Bicycle health review: cost, pros & cons, & who it’s right for. ChoosingTherapy.com. Retrieved from https://www.choosingtherapy.com/bicycle-health-review
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Lieberman, A. (2025, May 23). Charlie health review 2025: cost, pros & cons, & who it’s right for. ChoosingTherapy.com. Retrieved from https://www.choosingtherapy.com/charlie-health-review/
We regularly update the articles on ChoosingTherapy.com to ensure we continue to reflect scientific consensus on the topics we cover, to incorporate new research into our articles, and to better answer our audience’s questions. When our content undergoes a significant revision, we summarize the changes that were made and the date on which they occurred. We also record the authors and medical reviewers who contributed to previous versions of the article. Read more about our editorial policies here.
Author: Melissa Boudin, PsyD (No change)
Medical Reviewer: Kristen Fuller, MD (No change)
Primary Changes: Added Affect Therapeutics; added QuickMD to “Other Options” list.
Author: Melissa Boudin, PsyD (No change)
Medical Reviewer: Kristen Fuller, MD (No change)
Primary Changes: Added “Other Options to Consider;” Updated FAQs; Updated formatting throughout; Fact-checked and edited for readability and clarity.
Author: Melissa Boudin, PsyD (New author)
Medical Reviewer: Kristen Fuller, MD (New medical reviewer)
Primary Changes: Fact-checked all information for factual accuracy, along with improving readability. Updated pricing throughout (Workit Health: From “Depends on program & insurance” to $150 – $300 monthly; Eleanor Health: From “Depends on program & insurance” to $249 monthly; PursueCare: From $85 to $245+ monthly to $50 per session; Ophelia: From $195 monthly to $245 monthly; Ria Health: From $449.00 monthly to $175 – $449 monthly). Updated list order. Removed Bicycle Health from main list. Renamed Categories (PursueCare is now Best for Multiple Addictions instead of Most Personalized Pharmacy Services).
Author: Melissa Boudin, PsyD (New author)
Medical Reviewer: Kristen Fuller, MD (New medical reviewer)
Primary Changes: Fact-checked all information for factual accuracy, along with improving readability. Updated pricing throughout (Bicycle Health: From $199 monthly to $249 monthly.) Reordered to move Ophelia and Ria Health higher on the list.
Author: Melissa Boudin, PsyD (New author)
Medical Reviewer: Kristen Fuller, MD (New medical reviewer)
Primary Changes: Complete rewrite of article. Fact-checked all information and reconsidered/made changes to the recommendations list based on research and product testing. Updated where necessary to improve factual accuracy and readability. Companies removed from list: Monument. Companies added to list: None.
Author: Randi Sprintis, MS (No change)
Medical Reviewer: Benjamin Troy, MD (No change)
Primary Changes: Complete revamp of overall style; updated logos for all companies.
Author: Randi Sprintis, MS
Original Medical Reviewer: Benjamin Troy, MD
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