Cialis (Tadalafil): Dosage, Side Effects, How Long it Lasts, & More

What Is Cialis?

Cialis, the brand name for the generic drug tadalafil, belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors. This drug class primarily works by relaxing the smooth muscles in blood vessel walls, increasing blood flow to specific body areas. Cialis’s main physiological effect is improving blood circulation, particularly in the genital area.²

FDA approval signifies that the U.S. Food and Drug Administration has evaluated the drug’s safety and effectiveness, deeming it suitable for treating specific conditions. In the case of Cialis, it is FDA-approved for the treatment of erectile dysfunction (ED) in men. This condition involves the inability to achieve or maintain an erection sufficient for sexual activity.

Is Cialis Available as a Generic Medication?

Yes, generic versions of Cialis are available and often marketed under tadalafil. These generics contain the same active ingredient and are similarly effective. Opting for the generic form can offer a cost-effective alternative without compromising the medication’s performance.³

How Does Cialis Work?

Cialis, or tadalafil, works by inhibiting the enzyme phosphodiesterase type 5. This inhibition relaxes the smooth muscles in the blood vessels, particularly in the penis, allowing increased blood flow. Consequently, this enhanced circulation supports the achievement and sustenance of erections. It’s important to note that Cialis doesn’t induce arousal; it simply facilitates the physiological response to sexual stimulation, aiding men in overcoming erectile dysfunction.¹

What Is Cialis Used to Treat?

Cialis is FDA-approved to treat erectile dysfunction (ED), a condition characterized by the inability to achieve or sustain an erection sufficient for sexual activity. Cialis is also approved for treating benign prostatic hyperplasia (BPH), characterized by an enlarged prostate.²

Furthermore, Cialis is used as an off-label treatment for pulmonary arterial hypertension (PAH). Healthcare providers may prescribe Cialis for non-FDA-approved uses, known as off-label use. An off-label use occurs when a medication is employed for a condition not explicitly approved by the FDA, based on the prescriber’s professional judgment and belief in potential benefits.

How Effective is Cialis?

Cialis has shown remarkable effectiveness in treating ED. Clinical studies have indicated that tadalafil, the active ingredient in Cialis, can help up to 81% of men achieve and maintain erections sufficient for sexual intercourse. Its long-lasting effects, lasting up to 36 hours, make it a preferred choice for many individuals.²

Is Generic Cialis (Tadalafil) as Effective as Cialis?

Generic Cialis (Tadalafil) is equivalent in effectiveness to the brand-name Cialis. Both contain the same active ingredient, Tadalafil and work in the same way to treat erectile dysfunction.¹

Is Cialis Stronger Than Viagra?

Cialis and Viagra are both PDE5 inhibitors used to treat erectile dysfunction, but they have some differences in terms of onset of action and duration of effect. Cialis is often referred to as the “weekend pill” because its action can last for up to 36 hours, while Viagra typically lasts for about 4-5 hours. The duration of action means that a man who takes the medication has the potential to achieve an erection when aroused during the time that the medication is active. It does not mean that an erection would last for 4-5 hours with Viagra or 36 hours with Cialis.

Cialis Warnings & Precautions

Before considering Cialis, it is essential to be aware of certain warnings and precautions associated with the medication. Medical attention may be necessary if any adverse effects occur.

Avoid taking Cialis if you:²

• Have cardiovascular conditions: Cialis may exacerbate cardiovascular issues; consult a healthcare professional before use.
• Experience vision loss: In rare cases, individuals using Cialis have reported sudden vision loss. Seek immediate medical attention if you experience any vision loss.
• Use nitrates: Concurrent use of nitrates can lead to a dangerous drop in blood pressure; inform your healthcare provider if you are prescribed nitrates.
• Have a history of priapism: Cialis users who have ever experienced priapism (prolonged erections) should discuss the safety of this drug with their doctor, as the drug may increase the risk of recurrence.
• Are allergic to tadalafil: Allergic reactions, although uncommon, can occur; discontinue use and seek medical assistance if allergic symptoms arise.
• Have liver or kidney impairment: Adjustments to Cialis dosage may be necessary in individuals with impaired liver or kidney function; consult a healthcare provider.
• Are advised against sexual activity: Individuals with certain medical conditions are often advised against engaging in sexual activity; Cialis use in such cases should be discussed with a healthcare professional.

Common Side Effects of Cialis

Cialis may cause common side effects that vary in intensity. While these effects are usually mild, it’s essential to be aware of them. Not everyone will experience these, but if you do, consulting your doctor is crucial.

Common side effects of Cialis include:¹

• Headaches
• Muscle pain
• Indigestion
• Back pain
• Nasal congestion

*All medications, including Cialis, can cause side effects which can be mild or serious. This is not a comprehensive list of all possible side effects. You should talk with your doctor about any questions you have and to understand the potential side effects and benefits of any medication.

Serious Side Effects of Cialis

While Cialis is generally well-tolerated, serious side effects require immediate medical attention. These effects, though rare, can impact vital bodily functions. Seek urgent care if you experience vision changes, an allergic reaction, chest pain, or a prolonged erection.

Serious side effects of Cialis include:¹

• Sudden vision loss
• Sudden hearing loss
• Chest pain
• Priapism
• Severe dizziness
• Allergic reactions
• Shortness of breath
• Irregular heartbeat
• Swelling of the ankles, hands, or feet
• Seizures

*All medications, including Cialis, can cause side effects which can be mild or serious. This is not a comprehensive list of all possible side effects. You should talk with your doctor about any questions you have and to understand the potential side effects and benefits of any medication.

Cialis Dosages for FDA-Approved Treatment

Cialis, approved by the FDA, offers a tailored approach to dosage, recognizing that individuals vary in response. The typical Cialis dosage range is between 2.5mg to 20mg, with factors like age, the condition being treated, and individual health influencing prescription decisions. Cialis is approved for use in adults, spanning various age groups, emphasizing the importance of personalized dosing for optimal effectiveness.²

Cialis Forms & Strengths

Cialis offers diverse forms and strengths, enhancing its adaptability to individual requirements. Prescribers consider factors like patient preferences, the immediacy of effect needed, and potential side effects.

Cialis is primarily available in oral tablets, with strengths ranging from 2.5 to 20 mg. The extended-release and delayed-release versions offer options for specific needs. The selection of a form and strength hinges on a patient’s condition, lifestyle, and the desired onset of action.

Cialis is available in the following forms and strengths:²

• 2.5 milligrams (mg) oral tablet
• 5 milligrams (mg) oral tablet
• 10 milligrams (mg) oral tablet
• 20 milligrams (mg) oral tablet

What’s the Most Effective Dose of Cialis?

The most effective dose of Cialis varies among individuals and is determined through a collaborative effort between the patient and their healthcare provider. Factors such as the condition, response to treatment, and any existing health conditions influence the optimal dosage.

How Should I Take Cialis?

To take Cialis (tadalafil) effectively, following your prescriber’s instructions carefully is crucial. Typically, Cialis is prescribed as needed to treat erectile dysfunction. The recommended starting dose is usually 10 mg, but it can vary depending on your circumstances. It’s important to take Cialis at least 30 minutes before anticipated sexual activity. The potential to have an erection in response to sexual stimulation can last up to 36 hours, so you don’t need to rush. Don’t exceed the prescribed dose, and never take multiple doses within 24 hours.

Cialis can be taken with or without food, as food does not significantly affect absorption. However, it’s advisable to avoid excessive alcohol consumption while taking Cialis, as it may increase the risk of experiencing side effects. Always consult your healthcare provider for personalized dosing and timing instructions, as they can make recommendations based on your medical history and needs.¹

What Happens If I Miss a Dose of Cialis?

If you miss a dose of Cialis, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed one. Do not double up on doses to compensate for a missed one, as this can increase the risk of side effects.¹

How Long Does Cialis Last?

Cialis has a prolonged duration of action compared to other erectile dysfunction medications, affecting how long Cialis stays in the body. The effects of Cialis can last up to 36 hours, providing a more flexible window for sexual activity.²

Why Does Cialis Take 12-14 Hours to Work?

The extended duration of action of Cialis is attributed to its unique pharmacokinetics. Unlike other erectile dysfunction medications, Cialis has a longer half-life, allowing it to remain active in the body for an extended period. This characteristic enables users to engage in sexual activity with greater spontaneity, as the medication doesn’t have to be taken immediately before the planned activity.

Can You Overdose on Cialis?

Exceeding the prescribed dosage can increase the risk of adverse effects, including severe headaches and dizziness. If you experience overdose symptoms, such as difficulty breathing or a prolonged erection lasting more than four hours, seek immediate medical attention.³

What Should You Do If You Take Too Much Cialis?

If you suspect you’ve taken too much Cialis, seek emergency medical attention. Contacting your healthcare provider or going to the nearest emergency room is crucial. Be prepared to provide information on the amount ingested and any symptoms experienced. Timely intervention is vital to mitigate potential complications associated with an overdose.³

What to Avoid When Taking Cialis

When taking Cialis, one must be aware of potential interactions with other substances, including medications, substances, and herbs. These interactions can impact the effectiveness of Cialis and may lead to adverse effects.

10 substances you should avoid while taking Cialis include:²

• Nitrates: These medications, commonly prescribed for chest pain (angina), can cause a dangerous drop in blood pressure when combined with Cialis.
• Alpha-blockers: Drugs used to treat high blood pressure and prostate conditions. Combining them with Cialis can lead to a significant decrease in blood pressure.
• Antifungal medications (azole antifungals): Certain antifungal drugs can increase the concentration of Cialis in the blood, potentially leading to side effects.
• HIV protease inhibitors: Medications used to treat HIV/AIDS. They can increase the likelihood of side effects when taken with Cialis.
• Macrolide antibiotics: Antibiotics like erythromycin can affect the metabolism of Cialis, potentially increasing the risk of side effects.
• Riociguat: A medication used for pulmonary arterial hypertension. Combining it with Cialis can lead to severe hypotension.
• GrapefruitjJuice: Grapefruit and grapefruit juice can interfere with the metabolism of Cialis, increasing its concentration in the blood and the risk of side effects.
• Rifampin: An antibiotic used to treat bacterial infections. It may decrease the effectiveness of Cialis.
• St. John’s wort: An herbal supplement used for various purposes. It can decrease the concentration of Cialis in the blood, reducing its effectiveness.
• Alcohol: While moderate alcohol consumption is generally acceptable, excessive alcohol intake can increase the risk of side effects such as dizziness and headache when combined with Cialis.

How to Get a Prescription for Cialis

Obtaining a prescription for Cialis (tadalafil) involves consulting a healthcare professional. Since Cialis is a prescription-only medication, you cannot purchase it over the counter. A primary care physician, urologist, or healthcare provider specializing in sexual health can prescribe Cialis.

During the consultation, your doctor will inquire about your medical history, current medications, and any existing health conditions. A physical examination may be conducted to assess your overall health, and you might discuss your sexual health concerns.²

How Much Does Cialis Cost?

The cost of Cialis can vary widely depending on several factors, including the dosage, the number of tablets in a prescription, and whether you choose the brand-name or generic version of the medication. Cialis is available in different strengths, such as 5 mg, 10 mg, and 20 mg. The cost for a single tablet of Cialis ranged from approximately $10 to $70 per tablet, while generic versions were generally more affordable, starting at around $1 to $2 per tablet.⁴

It’s important to note that prices can change over time, and various factors, including insurance coverage, discounts, and coupons for Cialis, can influence the final cost. Many pharmacies offer savings programs and discounts for Cialis; some online pharmacies may provide competitive pricing. To obtain the most accurate and up-to-date pricing information, it’s recommended to check with local pharmacies or use online tools and resources.

Cialis Alternatives

There are several alternatives to Cialis for the treatment of erectile dysfunction. These alternatives include:

Viagra

Viagra (sildenafil) is another popular medication for erectile dysfunction. Like Cialis, it belongs to the class of PDE5 inhibitors. While both medications work similarly, there are differences in their onset of action and duration of effectiveness. Viagra typically takes effect within 30 minutes and lasts about four hours, making it suitable for shorter-term use than the longer-lasting Cialis.⁵

Stendra

Stendra (avanafil) is a newer medication for erectile dysfunction, known for its fast onset of action. It can start working in as little as 15 minutes, making it a quicker option than Cialis and Viagra. Stendra also has a shorter duration of action, usually lasting up to six hours.⁶ The choice between Stendra, Cialis, and Viagra often depends on individual preferences and how well the medication aligns with personal needs and lifestyle.

Levitra

Levitra (vardenafil) is another PDE5 inhibitor used to treat erectile dysfunction. It shares similarities with Cialis and Viagra regarding efficacy but may have a faster onset than Cialis. Levitra typically takes effect within 30 minutes and lasts for about five hours.² Like other erectile dysfunction medications, the choice between Levitra and Cialis depends on individual factors, including the desired duration of action and any specific health considerations.

Questions to Ask Your Healthcare Provider About Cialis

When considering Cialis, engaging with your healthcare team, including your doctor, psychiatrist, and therapist, is crucial to ensure a comprehensive understanding of its implications. This is especially relevant if you’re exploring Cialis for erectile dysfunction or other conditions. If you’re considering a switch or starting with online psychiatry services, asking the right questions is vital to ensure a smooth transition.

Questions to ask your care team about Cialis include:

• How safe is Cialis?
• How long will it take for me to adjust to taking Cialis?
• Am I at risk for more serious symptoms if I am already taking other medications?
• What is the best dosage to ensure fewer side effects?
• Are there any lifestyle changes I should consider while on Cialis?
• How often should I take Cialis, and is it suitable for daily use?
• What are the potential interactions between Cialis and my current medications?
• How long should I continue taking Cialis, and when should I expect to see results?
• Are there any specific health conditions affecting my ability to take Cialis safely?
• What should I do if I experience side effects or if the medication is not working as expected?
• Is there a generic version of Cialis available, and would it be a suitable option for me?
• Can you provide information on potential lifestyle modifications to complement the effects of Cialis?
• What if I need to consider a different medication, such as comparing Cialis vs Levitra?

For Further Reading

• Sexual Disorders: Types, Symptoms, Causes & Treatments
• Sexual Anxiety: Types, Symptoms, Treatments, & More
• Sexual Performance Anxiety: Causes, Treatments, & How to Cope
• Does Porn Cause Erectile Dysfunction?
• Sensate Focus Therapy: How It Works & What to Expect